iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000008160.3	ENSMMUT00000068457.1	ENSMMUP00000051437.1
ENSMMUG00000008160.3	ENSMMUT00000011401.3	ENSMMUP00000010685.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.30e-11	42.6	180	233
ULD/UDP/UFD/PB1	6.70e-20	72.2	242	334

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            ++l+d++++++ eL++k+Gdv++++     +++Wl+g  + +g  G+fP  Fv+ l+
   Q: 180  AEALFDFTGNSKLELNFKAGDVIFLL--SRINKDWLEG--TVRGATGIFPLSFVKILK 233
           689***********************..999*******..8*************9776 PP

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirs......faldlekpgkfedLlkavrtltelknsevalkYeDedGDlvtlksDedldkavslla...skksll..r 78
           t++++++y++++ s      +++dl+++++f+dLl+++r+  e++++++al+Y+D++GDlv+l sDed+  +v+ ++   s+k+l+  +
   Q: 242  TNWLRCYYYDDTVStvkdiaVEEDLSSTPLFKDLLELTRR--EFQREDIALNYRDAEGDLVRLLSDEDVVLMVRKARglpSQKRLFpwK 328
           589*********99**************************..********************************999************ PP
   S: 79   lliqkk 84
           l+i++k
   Q: 329  LHITQK 334
           ***985 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MDSNVLDYNL AIAIWLDFEQ LPDDVAISAN IADIEEKRGF TSHFVFVIEV KTKGGSKYLI 60
YRRYRQFYAL QSKLEERFGP DSKSSALACT LPTLPAKVYV GVKQEIAEMR IPALNAYMKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCAAGAAAG CCTGGAGGAG GAGCCTCTGC CAGAGTGGAG AGAAGCAGGC CTGAGCCTCC 60
CCAAAGGCAG CTCTTGGGGA CTCCCAGGAC CGCAGGCTGA GACGAGAAGC AGGGTGGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000919--NCF_P40
IPR000270--PB1_dom
IPR001683--Phox
IPR001452--SH3_domain

PROSITE

PS51745--PB1
PS50195--PX
PS50002--SH3

Pfam

PF00564--PB1
PF00787--PX
PF00018--SH3_1

PRINTS

PR00497--P40PHOX

SMART

SM00666--PB1
SM00312--PX
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0010008--C:endosome membrane
GO:0043020--C:NADPH oxidase complex
GO:0005802--C:trans-Golgi network
GO:0005086--F:ARF guanyl-nucleotide exchange factor activity
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0016176--F:superoxide-generating NADPH oxidase activator activity
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001675	Ailuropoda melanoleuca	88.41	1.00e-173	602.00
IUUC-Apl-003431	Anas platyrhynchos	68.90	2.00e-133	468.00
IUUC-Aca-005176	Anolis carolinensis	73.01	1.00e-137	482.00
IUUC-Ame-011492	Astyanax mexicanus	56.98	6.00e-110	390.00
IUUC-Bta-013434	Bos taurus	89.33	1.00e-163	568.00
IUUC-Cja-019788	Callithrix jacchus	94.21	0.00e+00	639.00
IUUC-Cfa-021039	Canis familiaris	89.02	6.00e-169	586.00
IUUC-Cpo-021848	Cavia porcellus	88.11	1.00e-169	588.00
IUUC-Csa-023733	Chlorocebus sabaeus	98.98	1.00e-172	598.00
IUUC-Dre-027732	Danio rerio	54.78	1.00e-94	339.00
IUUC-Dno-029154	Dasypus novemcinctus	80.06	9.00e-152	529.00
IUUC-Eca-034062	Equus caballus	89.94	6.00e-171	593.00
IUUC-Eeu-035129	Erinaceus europaeus	78.43	4.00e-67	248.00
IUUC-Fca-036402	Felis catus	89.94	3.00e-177	613.00
IUUC-Fal-037105	Ficedula albicollis	68.60	7.00e-132	463.00
IUUC-Gmo-039144	Gadus morhua	47.50	3.00e-33	134.00
IUUC-Gga-040526	Gallus gallus	69.51	4.00e-133	467.00
IUUC-Ggo-044667	Gorilla gorilla	97.17	1.00e-142	498.00
IUUC-Hsa-045779	Homo sapiens	97.56	0.00e+00	662.00
IUUC-Itr-048385	Ictidomys tridecemlineatus	69.86	3.00e-126	444.00
IUUC-Lch-050264	Latimeria chalumnae	54.39	1.00e-112	399.00
IUUC-Loc-051887	Lepisosteus oculatus	54.23	5.00e-101	360.00
IUUC-Laf-054411	Loxodonta africana	82.67	1.00e-155	541.00
IUUC-Meu-056875	Macropus eugenii	82.32	4.00e-94	337.00
IUUC-Mga-059737	Meleagris gallopavo	68.90	7.00e-132	463.00
IUUC-Mmr-061065	Microcebus murinus	91.95	2.00e-128	451.00
IUUC-Mdo-062598	Monodelphis domestica	81.16	3.00e-153	534.00
IUUC-Mmu-063643	Mus musculus	86.59	5.00e-171	593.00
IUUC-Mpu-066142	Mustela putorius furo	90.55	9.00e-180	622.00
IUUC-Mlu-067898	Myotis lucifugus	81.11	2.00e-39	152.00
IUUC-Nle-069935	Nomascus leucogenys	84.92	8.00e-154	536.00
IUUC-Opr-070204	Ochotona princeps	85.94	5.00e-129	453.00
IUUC-Ont-072261	Oreochromis niloticus	54.28	1.00e-101	362.00
IUUC-Oan-072846	Ornithorhynchus anatinus	82.19	4.00e-70	256.00
IUUC-Ocu-074683	Oryctolagus cuniculus	90.58	3.00e-178	617.00
IUUC-Ola-086700	Oryzias latipes	54.14	8.00e-95	340.00
IUUC-Oga-087992	Otolemur garnettii	92.68	0.00e+00	628.00
IUUC-Oar-089828	Ovis aries	88.18	9.00e-161	559.00
IUUC-Pan-092264	Papio anubis	97.87	0.00e+00	663.00
IUUC-Psi-093800	Pelodiscus sinensis	69.21	9.00e-130	456.00
IUUC-Pfo-096677	Poecilia formosa	51.59	7.00e-85	307.00
IUUC-Pab-097920	Pongo abelii	96.04	0.00e+00	653.00
IUUC-Pca-100312	Procavia capensis	71.49	5.00e-94	337.00
IUUC-Pva-102113	Pteropus vampyrus	89.52	7.00e-132	463.00
IUUC-Rno-105777	Rattus norvegicus	87.20	4.00e-172	597.00
IUUC-Sha-106666	Sarcophilus harrisii	81.16	4.00e-161	560.00
IUUC-Ssc-116056	Sus scrofa	88.41	3.00e-176	610.00
IUUC-Tgu-116797	Taeniopygia guttata	69.21	2.00e-134	471.00
IUUC-Tru-117860	Takifugu rubripes	53.24	3.00e-95	341.00
IUUC-Tsy-119537	Tarsius syrichta	92.12	4.00e-88	317.00
IUUC-Tni-119946	Tetraodon nigroviridis	54.49	4.00e-97	348.00
IUUC-Tca-121171	Theobroma cacao	38.10	2.00e+00	27.30
IUUC-Tbe-127274	Tupaia belangeri	73.88	2.00e-101	362.00
IUUC-Ttr-129026	Tursiops truncatus	89.90	4.00e-105	374.00
IUUC-Xtr-131910	Xenopus tropicalis	53.35	1.00e-105	376.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence