iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053469

UUCD1 version

UUC-LoA-00707

Ensembl Protein ID

ENSLAFP00000018475.1

UniProt Accession

G3TSB7; G3TSB7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

ZNRF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000028501.1	ENSLAFT00000030710.1	ENSLAFP00000018475.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-07	32.7	223	266

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl+++++g  +++lpC H++h  C+  w      +  + +CP C+
   Q: 223  CAICLDEYEEGdqLKILPCSHTYHCRCIDPW----FAQAARRTCPMCK 266
           ********55555******************....9999999*****6 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

VAMGRWWPAP ALVVIKTSLI LLVLLAPSQA LVRAILDSNS STMDFADLPA LFGVPLAPEG 60
LRGYLMEAKP ANACQPIERP RLGNSSLGAI VLIRRYDCTF DLKVLHAQRA GFEAAIVHNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGCCATGG GGAGGTGGTG GCCAGCCCCG GCCCTGGTGG TCATCAAGAC TTCGCTGATC 60
CTGCTGGTAC TGCTGGCACC CTCACAGGCC CTGGTGCGAG CCATACTGGA CAGTAACTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001654	Ailuropoda melanoleuca	76.25	3.00e-124	438.00
IUUC-Bta-012572	Bos taurus	71.26	1.00e-114	406.00
IUUC-Cja-019445	Callithrix jacchus	69.12	7.00e-110	390.00
IUUC-Cfa-020828	Canis familiaris	77.70	2.00e-116	412.00
IUUC-Csa-023281	Chlorocebus sabaeus	69.41	5.00e-101	361.00
IUUC-Dor-030690	Dipodomys ordii	53.01	2.00e-53	202.00
IUUC-Ete-032610	Echinops telfairi	74.57	2.00e-118	418.00
IUUC-Ggo-045531	Gorilla gorilla	68.73	3.00e-103	368.00
IUUC-Hsa-045802	Homo sapiens	70.78	8.00e-104	370.00
IUUC-Itr-048891	Ictidomys tridecemlineatus	72.44	6.00e-105	373.00
IUUC-Mcc-054662	Macaca mulatta	71.34	2.00e-101	362.00
IUUC-Meu-056499	Macropus eugenii	56.99	1.00e-91	328.00
IUUC-Mdo-062468	Monodelphis domestica	53.54	4.00e-91	327.00
IUUC-Mmu-064409	Mus musculus	53.12	2.00e-63	235.00
IUUC-Mpu-066553	Mustela putorius furo	74.78	1.00e-119	422.00
IUUC-Oan-073710	Ornithorhynchus anatinus	47.31	7.00e-61	227.00
IUUC-Ptr-090842	Pan troglodytes	68.40	1.00e-101	362.00
IUUC-Pan-092278	Papio anubis	71.34	2.00e-101	362.00
IUUC-Pab-097537	Pongo abelii	72.73	5.00e-101	360.00
IUUC-Rno-104830	Rattus norvegicus	50.19	5.00e-58	217.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence