iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097537

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01236479

Gene Name

ZNRF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000009425.1	ENSPPYT00000010984.1	ENSPPYP00000010569.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.50e-09	35.9	309	352

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl+++++g  +++lpC H++h +C+  w     s+ ++ +CP+C+
   Q: 309  CAICLDEYEEGdqLKILPCSHTYHCKCIDPW----FSQAPRRSCPVCK 352
           ********55555******************....9***********7 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

TLLCRPEHLM PRATRVTVAA SLPLNHAVIP TQLPSHPGHR PPGRPLRCPK ASGLPSPVGP 60
SSTQPAKRVT MGWPRPGRAL LAVKSLLVLS LLQVPAQAVV RAMLEDNSSS VDFADLPALF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGCTGCTCT GCCGTCCGGA GCACTTAATG CCTAGGGCCA CCAGGGTCAC GGTGGCTGCG 60
TCACTGCCTC TGAACCACGC GGTCATTCCA ACTCAACTGC CTTCGCATCC TGGCCACAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001654	Ailuropoda melanoleuca	73.12	1.00e-146	513.00
IUUC-Bta-012572	Bos taurus	68.92	4.00e-125	441.00
IUUC-Cja-019445	Callithrix jacchus	81.50	1.00e-160	559.00
IUUC-Cfa-020828	Canis familiaris	74.71	1.00e-130	459.00
IUUC-Csa-023281	Chlorocebus sabaeus	93.93	0.00e+00	644.00
IUUC-Ete-032610	Echinops telfairi	69.35	2.00e-131	461.00
IUUC-Ggo-045531	Gorilla gorilla	92.33	0.00e+00	651.00
IUUC-Hsa-045802	Homo sapiens	92.74	0.00e+00	655.00
IUUC-Itr-048891	Ictidomys tridecemlineatus	77.15	9.00e-116	409.00
IUUC-Laf-053469	Loxodonta africana	70.18	2.00e-122	431.00
IUUC-Mcc-054662	Macaca mulatta	94.16	0.00e+00	647.00
IUUC-Meu-056499	Macropus eugenii	59.07	1.00e-97	349.00
IUUC-Mdo-062468	Monodelphis domestica	57.39	2.00e-99	355.00
IUUC-Mmu-064409	Mus musculus	53.44	8.00e-65	240.00
IUUC-Mpu-066553	Mustela putorius furo	74.26	4.00e-145	507.00
IUUC-Oan-073710	Ornithorhynchus anatinus	51.33	2.00e-69	256.00
IUUC-Ptr-090842	Pan troglodytes	91.38	4.00e-180	623.00
IUUC-Pan-092278	Papio anubis	94.39	0.00e+00	652.00
IUUC-Ppa-095724	Physcomitrella patens	31.30	2.00e-22	100.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence