iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069473

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01065876

Gene Name

LOC100607498; LOC100604556

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000019346.1	ENSNLET00000024371.1	ENSNLEP00000023183.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.50e-78	263.1	81	374

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+N+gNtCY+N+ LQcL+ +p+l++++l+ ++++++++     +k ++l+++q  ++  +++  ++++p++ l      a  f+  +q
   Q: 81   GLQNMGNTCYVNASLQCLTYTPPLANYMLSrEHSQTCHR-----HKCCMLCTMQAHITRALHRPGHVIQPSQAL------AAGFHRGKQ 158
           9*****************************555555554.....589*******99999999999999999755......456999*** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl+f +d++++++                  l+ +++ ++++k ++li+++F+g ++sqikcl+c+ +s +++p ld+ l+++ 
   Q: 159  EDAHEFLMFTVDAMRKAC------------------LPGHKQVDPHSKDTTLIHQIFGGYWRSQIKCLHCQGISDTFDPYLDIALDIQA 229
           ******************..................78888999********************************************* PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            +     s++++Le+ +k+eel+gen+y+c  c +k  a+k+l+l++  +vLil LkRf  s      +k+ k+v++p+ Ld++p++++
   Q: 230  AQ-----SVKQALEQLVKPEELNGENAYHCGLCLQKAPASKTLTLHTSAKVLILVLKRF--S--DVTGNKLAKNVQYPECLDMQPYMSQ 309
           **.....9***************************************************..3..35778******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           ++++   +  Y L+av+vH G s+++GHY++yvk ++g+W+++dD +Vt++  ++vl+   ++aYvlfY +
   Q: 310  QNTG---PLVYVLYAVLVHAGwSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLS---QQAYVLFYIQ 374
           8876...89*************************************************...********86 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MEHDSLYSGG EWHFNRFSKL TSSRPHAAFA EIQRTSLPEK SPLSSETRVD PCDDLAPVAR 60
QLAPREKLPL SSRGPAAVGA GLQNMGNTCY VNASLQCLTY TPPLANYMLS REHSQTCHRH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCACG ACTCACTCTA CTCGGGGGGT GAGTGGCACT TCAACCGCTT TTCAAAACTC 60
ACATCTTCTC GGCCACATGC AGCTTTTGCT GAAATCCAGC GGACTTCTCT CCCTGAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006861--HABP4_PAIRBP1-bd
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF04774--HABP4_PAI-RBP1
PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

nle:100604556; nle:100607498

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002148	Ailuropoda melanoleuca	57.52	2.00e-161	562.00
IUUC-Cfa-020232	Canis familiaris	54.16	3.00e-146	511.00
IUUC-Eeu-035019	Erinaceus europaeus	55.88	2.00e-97	348.00
IUUC-Ggo-045374	Gorilla gorilla	93.40	0.00e+00	1009.00
IUUC-Hsa-046171	Homo sapiens	92.64	0.00e+00	974.00
IUUC-Itr-048248	Ictidomys tridecemlineatus	61.16	3.00e-178	618.00
IUUC-Mcc-055149	Macaca mulatta	87.33	0.00e+00	910.00
IUUC-Opr-070217	Ochotona princeps	56.35	6.00e-124	437.00
IUUC-Oar-089605	Ovis aries	50.84	4.00e-136	478.00
IUUC-Ptr-091297	Pan troglodytes	93.21	0.00e+00	973.00
IUUC-Pan-092066	Papio anubis	86.77	0.00e+00	905.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence