iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Rno-105845

UUCD1 version

UUC-RaN-01096

Ensembl Protein ID

ENSRNOP00000070218.1

UniProt Accession

A0A0G2JXC4; A0A0G2JXC4_RAT

Protein Name

Similar to ubiquitin-specific peptidase 17 (homolog)

Gene Name

LOC689730

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000054939.1	ENSRNOT00000077148.1	ENSRNOP00000070218.1

Annotation

Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.90e-78	262.0	72	367

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           Gl+N+gN+CY+N+vLQcL+++p+l++++l+ ++++++       p+g+ +++++  +++ +  +++ ++++p+e+l++       f++ 
   Q: 72   GLQNIGNSCYLNAVLQCLTHTPPLADYMLSqEHSQRC-----CYPEGCKMCAMEAHVTQSLlhSHSGGVMKPSEILTST------FHKH 149
           9*****************************4444444.....35778888888777777665788889******98765......8899 PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +q+Da+Efl+f l++++e++                  l   +++++ +k +sli d+F+gq++sqikc +c+ +  +++pfl l l++
   Q: 150  RQEDAHEFLMFTLNAMHESC------------------LRGCKQSETSSKDSSLIYDIFGGQMRSQIKCHHCQGTLDSYDPFLNLFLDI 220
           9*******************..................334457789999*************************************** PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
            + +     s++++Le+ +k eel+g+n+yyc +c++k  a+k++k+++ ++vL l L+R  ++       k+n+ v++p+ Ldl+p++
   Q: 221  CSAQ-----SVKQALEDLVKLEELQGDNAYYCGRCREKMPASKTTKVQTASKVLLLVLNRS-YDF---GGDKLNRVVSYPEYLDLQPYL 300
           ****.....9**************************************************9.655...678****************** PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           ++p+ +   +  Y L+av+vH G ++ssGHY++yvk ++gkW+++dDskVt ++ ++vl+   + aY+lfY +
   Q: 301  SQPTAG---PLPYALYAVLVHDGvTCSSGHYFCYVKASHGKWYKMDDSKVTRCDVSSVLS---EPAYLLFYVQ 367
           **9988...89*************************************************...********87 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

ERLPSADLED SSRLFERDHR KMVTAPSFTE DPAMSPPATP ELHQDEARVL EELSAKGKPS 60
LSLQRIQSPG SGLQNIGNSC YLNAVLQCLT HTPPLADYML SQEHSQRCCY PEGCKMCAME 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAGACTTC CTTCTGCTGA CTTAGAAGAT TCCAGCAGGT TATTCGAACG GGATCATAGA 60
AAAATGGTGA CTGCTCCCTC CTTCACAGAA GGTAAGTCTC ACTGTAAGGT CTTACATCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Hsa-046774	Homo sapiens	48.65	3.00e-116	412.00
IUUC-Itr-048248	Ictidomys tridecemlineatus	48.85	3.00e-125	441.00
IUUC-Mcc-055191	Macaca mulatta	48.54	1.00e-116	413.00
IUUC-Mmu-063581	Mus musculus	66.92	0.00e+00	682.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence