iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065829

Ensembl Protein ID

ENSMPUP00000007390.1

UniProt Accession

G9KW99; G9KW99_MUSPF

Genbank Protein ID

AES09178.1

Protein Name

Ubiquitin-conjugating enzyme E2S

Genbank Nucleotide ID

AEYP01089956

Gene Name

UBE2S

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000007446.1	ENSMPUT00000007510.1	ENSMPUP00000007390.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.90e-40	137.9	17	149

Active Site

Position(s)	Description	Evidence
95	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 3    kkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeek 91
           +ke+++l++dpp+gi++ p++e dlt+++v+i+Gpe+tpY+gg+F++++ + +d+P++PPk  fltkifhPnv +nG++C+++lk  ++
   Q: 17   YKEVTTLTADPPDGIKVFPNEE-DLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLK--RD 102
           79********************.9************************************************************9..** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           W++ l +++vll+i+ ll +pnpes+lneea +ll +n eey  ++r
   Q: 103  WTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYAARAR 149
           ******************************************99876 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MNSNVENLPP HIIRLVYKEV TTLTADPPDG IKVFPNEEDL TDLQVTIEGP EGTPYAGGLF 60
RMKLLLGKDF PASPPKGYFL TKIFHPNVGA NGEICVNVLK RDWTAELGIR HVLLTIKCLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGAGCG CGGAGGCCAG GCTTGGGAGG GGCGGCCGAG GGGCCCCACT AGAGGAGGAG 60
GCGGGGTCTC AGGAGCCTCT CGCGGACGGC CGGGCGGAGT GGGGGGGCCC GCCTGGGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0010458--P:exit from mitosis
GO:0010994--P:free ubiquitin chain polymerization
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000818	Aegilops tauschii	64.00	1.00e-48	186.00
IUUC-Aml-001979	Ailuropoda melanoleuca	97.54	2.00e-95	341.00
IUUC-Atr-002706	Amborella trichopoda	64.67	5.00e-48	184.00
IUUC-Aca-004432	Anolis carolinensis	77.72	3.00e-87	314.00
IUUC-Aly-005779	Arabidopsis lyrata	64.52	4.00e-58	217.00
IUUC-Ath-007162	Arabidopsis thaliana	65.16	2.00e-58	218.00
IUUC-Acl-008107	Aspergillus clavatus	50.81	5.00e-34	138.00
IUUC-Afl-008578	Aspergillus flavus	44.83	2.00e-34	139.00
IUUC-Afu-009034	Aspergillus fumigatus	51.18	9.00e-35	140.00
IUUC-Ani-009151	Aspergillus nidulans	52.34	7.00e-36	144.00
IUUC-Ang-009649	Aspergillus niger	51.16	7.00e-36	144.00
IUUC-Ame-010836	Astyanax mexicanus	59.61	1.00e-77	282.00
IUUC-Bta-012740	Bos taurus	100.00	5.00e-89	320.00
IUUC-Bdi-014057	Brachypodium distachyon	64.67	1.00e-48	186.00
IUUC-Bol-016481	Brassica oleracea	65.81	3.00e-58	218.00
IUUC-Bra-016867	Brassica rapa	65.16	2.00e-58	219.00
IUUC-Cja-019763	Callithrix jacchus	93.60	1.00e-96	345.00
IUUC-Cfa-020216	Canis familiaris	98.52	2.00e-98	350.00
IUUC-Cpo-021720	Cavia porcellus	87.25	2.00e-89	321.00
IUUC-Cre-022676	Chlamydomonas reinhardtii	60.67	2.00e-55	207.00
IUUC-Csa-023751	Chlorocebus sabaeus	94.09	5.00e-97	346.00
IUUC-Cho-024620	Choloepus hoffmanni	98.23	2.00e-63	233.00
IUUC-Cin-025632	Ciona intestinalis	59.79	2.00e-65	241.00
IUUC-Csv-025984	Ciona savignyi	67.10	2.00e-63	235.00
IUUC-Cne-026844	Cryptococcus neoformans	54.05	5.00e-48	184.00
IUUC-Cme-027294	Cyanidioschyzon merolae	58.06	3.00e-51	194.00
IUUC-Dre-027674	Danio rerio	62.04	2.00e-79	288.00
IUUC-Dno-029886	Dasypus novemcinctus	95.57	1.00e-89	322.00
IUUC-Dor-030440	Dipodomys ordii	93.60	1.00e-91	328.00
IUUC-Dse-031211	Dothistroma septosporum	47.06	4.00e-31	126.00
IUUC-Dme-031888	Drosophila melanogaster	67.97	9.00e-63	232.00
IUUC-Ete-032365	Echinops telfairi	78.77	8.00e-65	239.00
IUUC-Eca-033733	Equus caballus	93.60	5.00e-90	323.00
IUUC-Eeu-035342	Erinaceus europaeus	96.75	4.00e-86	310.00
IUUC-Fca-035964	Felis catus	100.00	1.00e-62	232.00
IUUC-Gmo-039357	Gadus morhua	66.19	3.00e-75	274.00
IUUC-Gga-040261	Gallus gallus	71.31	5.00e-47	180.00
IUUC-Gac-042593	Gasterosteus aculeatus	81.29	2.00e-76	278.00
IUUC-Gma-043597	Glycine max	64.00	1.00e-57	216.00
IUUC-Ggo-044626	Gorilla gorilla	92.86	9.00e-68	248.00
IUUC-Hsa-046058	Homo sapiens	94.09	7.00e-97	346.00
IUUC-Hvu-047281	Hordeum vulgare	64.67	5.00e-49	187.00
IUUC-Itr-048739	Ictidomys tridecemlineatus	95.07	9.00e-90	322.00
IUUC-Lch-049415	Latimeria chalumnae	71.70	1.00e-56	211.00
IUUC-Lpe-050956	Leersia perrieri	52.00	8.00e-33	133.00
IUUC-Lma-052996	Leptosphaeria maculans	52.78	4.00e-32	132.00
IUUC-Laf-053337	Loxodonta africana	94.06	5.00e-92	330.00
IUUC-Mcc-055485	Macaca mulatta	84.21	1.00e-93	335.00
IUUC-Meu-056123	Macropus eugenii	97.40	1.00e-86	312.00
IUUC-Mtr-058300	Medicago truncatula	64.00	1.00e-55	209.00
IUUC-Mla-059060	Melampsora laricipopulina	53.33	1.00e-48	186.00
IUUC-Mmr-061005	Microcebus murinus	93.10	3.00e-90	324.00
IUUC-Mdo-062979	Monodelphis domestica	97.60	1.00e-69	255.00
IUUC-Mmu-063778	Mus musculus	91.54	5.00e-92	330.00
IUUC-Mac-064680	Musa acuminata	64.67	2.00e-57	216.00
IUUC-Mlu-067498	Myotis lucifugus	95.45	6.00e-81	293.00
IUUC-Nfi-068520	Neosartorya fischeri	51.18	9.00e-35	140.00
IUUC-Nle-069727	Nomascus leucogenys	94.09	6.00e-97	346.00
IUUC-Opr-071066	Ochotona princeps	98.25	2.00e-63	233.00
IUUC-Ont-072363	Oreochromis niloticus	80.77	1.00e-74	272.00
IUUC-Oan-073383	Ornithorhynchus anatinus	95.24	2.00e-56	211.00
IUUC-Ocu-074599	Oryctolagus cuniculus	98.50	4.00e-75	273.00
IUUC-Oba-075186	Oryza barthii	65.33	1.00e-50	193.00
IUUC-Obr-076104	Oryza brachyantha	65.33	4.00e-49	187.00
IUUC-Ogl-077835	Oryza glaberrima	65.33	1.00e-50	192.00
IUUC-Ogu-078690	Oryza glumaepatula	65.33	1.00e-50	192.00
IUUC-Oin-080215	Oryza indica	65.33	1.00e-50	193.00
IUUC-Olo-080816	Oryza longistaminata	65.33	1.00e-50	193.00
IUUC-Ome-081657	Oryza meridionalis	65.33	2.00e-50	192.00
IUUC-Oni-082601	Oryza nivara	65.33	9.00e-51	193.00
IUUC-Opu-083367	Oryza punctata	66.00	2.00e-50	192.00
IUUC-Oru-084477	Oryza rufipogon	65.33	9.00e-51	193.00
IUUC-Osa-086119	Oryza sativa	65.33	1.00e-50	193.00
IUUC-Ola-086702	Oryzias latipes	81.94	6.00e-77	280.00
IUUC-Olu-087576	Ostreococcus lucimarinus	54.97	5.00e-47	180.00
IUUC-Oga-088946	Otolemur garnettii	92.12	5.00e-93	333.00
IUUC-Oar-089564	Ovis aries	100.00	3.00e-88	317.00
IUUC-Ptr-090620	Pan troglodytes	94.55	9.00e-97	345.00
IUUC-Pan-092382	Papio anubis	84.21	1.00e-93	335.00
IUUC-Psi-093891	Pelodiscus sinensis	89.47	6.00e-61	224.00
IUUC-Pma-094344	Petromyzon marinus	82.35	3.00e-75	274.00
IUUC-Pno-094981	Phaeosphaeria nodorum	47.93	9.00e-29	121.00
IUUC-Ppa-095452	Physcomitrella patens	60.39	9.00e-47	179.00
IUUC-Pfo-097288	Poecilia formosa	82.58	3.00e-77	281.00
IUUC-Pab-098506	Pongo abelii	94.09	6.00e-97	346.00
IUUC-Pop-098882	Populus trichocarpa	63.33	2.00e-57	215.00
IUUC-Pca-100749	Procavia capensis	93.10	2.00e-94	337.00
IUUC-Ppe-102084	Prunus persica	64.00	3.00e-57	214.00
IUUC-Pva-102755	Pteropus vampyrus	94.58	4.00e-92	330.00
IUUC-Pgr-103394	Puccinia graminis	54.30	5.00e-48	184.00
IUUC-Ptt-103750	Puccinia triticina	54.30	4.00e-48	184.00
IUUC-Pte-104240	Pyrenophora teres	50.00	3.00e-31	129.00
IUUC-Pyt-104483	Pyrenophora triticirepentis	49.22	9.00e-31	127.00
IUUC-Rno-105739	Rattus norvegicus	92.61	1.00e-98	351.00
IUUC-Smo-108939	Selaginella moellendorffii	60.00	5.00e-46	177.00
IUUC-Sit-109881	Setaria italica	65.33	2.00e-49	188.00
IUUC-Sly-111764	Solanum lycopersicum	62.67	3.00e-57	214.00
IUUC-Stu-111968	Solanum tuberosum	62.67	3.00e-57	214.00
IUUC-Sar-113093	Sorex araneus	63.59	5.00e-57	213.00
IUUC-Sbi-113842	Sorghum bicolor	66.00	3.00e-49	188.00
IUUC-Sre-115036	Sporisorium reilianum	44.30	5.00e-33	133.00
IUUC-Tru-117716	Takifugu rubripes	83.23	3.00e-77	280.00
IUUC-Tni-120210	Tetraodon nigroviridis	82.58	8.00e-77	279.00
IUUC-Tca-121315	Theobroma cacao	64.00	1.00e-57	216.00
IUUC-Tae-124474	Triticum aestivum	64.00	1.00e-48	186.00
IUUC-Tur-126669	Triticum urartu	64.00	1.00e-48	187.00
IUUC-Tme-127125	Tuber melanosporum	48.73	8.00e-39	154.00
IUUC-Tbe-128157	Tupaia belangeri	93.63	1.00e-88	318.00
IUUC-Ttr-128593	Tursiops truncatus	93.60	3.00e-95	340.00
IUUC-Uma-129592	Ustilago maydis	49.66	3.00e-40	157.00
IUUC-Vvi-131716	Vitis vinifera	63.33	1.00e-57	216.00
IUUC-Xtr-132592	Xenopus tropicalis	74.51	5.00e-83	300.00
IUUC-Xma-133064	Xiphophorus maculatus	79.11	7.00e-69	253.00
IUUC-Yli-134575	Yarrowia lipolytica	49.65	1.00e-37	149.00
IUUC-Zma-135328	Zea mays	64.00	2.00e-49	188.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence