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Tag Content
iUUCD ID IUUC-Cin-025390
Ensembl Protein ID ENSCINP00000008019.3
UniProt Accession F6TXB9; F6TXB9_CIOIN
Protein Name Tyrosine-protein kinase
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCING00000016554.2 ENSCINT00000008019.3 ENSCINP00000008019.3
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.10e-15 57.1 13 70
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
             +lydy+a + d+L++kkG+++++++ ++ +++W+++ +  ++  G +P+n+v+ ++
   Q: 13   YVALYDYDARTADDLSFKKGEQLFILNSTQSEGDWWEARSLVTQHTGYIPSNYVAPAN 70
           568***************************************************9876 PP
   
Organism Ciona intestinalis
Protein Sequence
(Fasta)
MPSRPSLQGQ VRYVALYDYD ARTADDLSFK KGEQLFILNS TQSEGDWWEA RSLVTQHTGY 60
IPSNYVAPAN SVQCEEWFFG KIGRKDSERL LLNQENLRGT FLIRESETAP GTFSLSILDE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cin-025390|UBD,SH3|Ciona intestinalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGATGATAGG ATAATCAGTA ATCAGTATAT ACATGTAAAT GAGCTAATAA GAAGAGCCGT 60
ACAAAACCAA ATCTGAAACT GAAAAACTCT TTTGTTTTGT CAAGTATGTT GTATGAAATG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cin-025390|UBD,SH3|Ciona intestinalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE
SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001713 Ailuropoda melanoleuca 69.94 0.00e+00 677.00
IUUC-Apl-004032 Anas platyrhynchos 71.64 0.00e+00 682.00
IUUC-Aca-004255 Anolis carolinensis 72.23 0.00e+00 682.00
IUUC-Ame-010954 Astyanax mexicanus 72.23 0.00e+00 677.00
IUUC-Bta-012982 Bos taurus 70.11 0.00e+00 677.00
IUUC-Cja-019694 Callithrix jacchus 72.23 0.00e+00 682.00
IUUC-Cfa-020060 Canis familiaris 70.54 0.00e+00 680.00
IUUC-Cpo-021557 Cavia porcellus 70.66 0.00e+00 679.00
IUUC-Csa-023711 Chlorocebus sabaeus 69.94 0.00e+00 678.00
IUUC-Cho-025014 Choloepus hoffmanni 70.93 0.00e+00 664.00
IUUC-Csv-026029 Ciona savignyi 95.65 0.00e+00 835.00
IUUC-Dre-028491 Danio rerio 70.84 0.00e+00 664.00
IUUC-Dno-029651 Dasypus novemcinctus 68.12 0.00e+00 669.00
IUUC-Dor-030202 Dipodomys ordii 72.67 0.00e+00 686.00
IUUC-Ete-033170 Echinops telfairi 68.82 0.00e+00 656.00
IUUC-Eca-033970 Equus caballus 71.33 0.00e+00 678.00
IUUC-Eeu-035004 Erinaceus europaeus 54.50 1.00e-111 394.00
IUUC-Fca-036113 Felis catus 70.54 0.00e+00 680.00
IUUC-Fal-037461 Ficedula albicollis 72.23 0.00e+00 683.00
IUUC-Gmo-038929 Gadus morhua 72.09 0.00e+00 665.00
IUUC-Gga-041107 Gallus gallus 71.64 0.00e+00 681.00
IUUC-Gac-042332 Gasterosteus aculeatus 69.51 0.00e+00 684.00
IUUC-Ggo-044469 Gorilla gorilla 70.72 0.00e+00 662.00
IUUC-Hsa-046192 Homo sapiens 69.94 0.00e+00 679.00
IUUC-Itr-049014 Ictidomys tridecemlineatus 69.94 0.00e+00 680.00
IUUC-Lch-050239 Latimeria chalumnae 72.89 0.00e+00 686.00
IUUC-Lpe-051534 Leersia perrieri 33.03 5.00e-20 91.70
IUUC-Loc-052812 Lepisosteus oculatus 70.72 0.00e+00 659.00
IUUC-Laf-053977 Loxodonta africana 69.94 0.00e+00 680.00
IUUC-Mcc-055626 Macaca mulatta 71.58 0.00e+00 675.00
IUUC-Meu-056155 Macropus eugenii 65.35 2.00e-175 607.00
IUUC-Mga-059310 Meleagris gallopavo 71.64 0.00e+00 681.00
IUUC-Mmr-061652 Microcebus murinus 72.02 0.00e+00 681.00
IUUC-Mdo-062963 Monodelphis domestica 71.58 0.00e+00 673.00
IUUC-Mmu-063893 Mus musculus 69.72 0.00e+00 677.00
IUUC-Mpu-066411 Mustela putorius furo 70.54 0.00e+00 680.00
IUUC-Mlu-067035 Myotis lucifugus 71.77 0.00e+00 677.00
IUUC-Nle-068978 Nomascus leucogenys 70.00 0.00e+00 654.00
IUUC-Opr-070299 Ochotona princeps 64.64 4.00e-172 596.00
IUUC-Ont-072127 Oreochromis niloticus 72.21 0.00e+00 682.00
IUUC-Oan-072997 Ornithorhynchus anatinus 71.40 0.00e+00 676.00
IUUC-Ocu-074403 Oryctolagus cuniculus 69.79 0.00e+00 676.00
IUUC-Obr-076855 Oryza brachyantha 32.11 4.00e-18 85.50
IUUC-Opu-083905 Oryza punctata 33.03 2.00e-19 90.10
IUUC-Ola-086527 Oryzias latipes 69.13 0.00e+00 681.00
IUUC-Oga-087957 Otolemur garnettii 72.23 0.00e+00 682.00
IUUC-Oar-090279 Ovis aries 70.11 0.00e+00 676.00
IUUC-Ptr-091050 Pan troglodytes 69.94 0.00e+00 679.00
IUUC-Pan-091862 Papio anubis 70.54 0.00e+00 679.00
IUUC-Psi-093310 Pelodiscus sinensis 72.07 0.00e+00 686.00
IUUC-Pma-094232 Petromyzon marinus 71.79 0.00e+00 689.00
IUUC-Pfo-096137 Poecilia formosa 71.21 0.00e+00 684.00
IUUC-Pab-097902 Pongo abelii 68.54 0.00e+00 676.00
IUUC-Pca-100245 Procavia capensis 70.93 0.00e+00 664.00
IUUC-Pva-102645 Pteropus vampyrus 70.72 0.00e+00 663.00
IUUC-Rno-105847 Rattus norvegicus 69.72 0.00e+00 677.00
IUUC-Sha-107539 Sarcophilus harrisii 70.02 0.00e+00 677.00
IUUC-Sit-110451 Setaria italica 31.46 5.00e-20 91.70
IUUC-Sar-113364 Sorex araneus 68.76 0.00e+00 638.00
IUUC-Ssc-115762 Sus scrofa 69.51 0.00e+00 677.00
IUUC-Tgu-117380 Taeniopygia guttata 72.23 0.00e+00 683.00
IUUC-Tru-117784 Takifugu rubripes 72.45 0.00e+00 681.00
IUUC-Tsy-119440 Tarsius syrichta 57.79 8.00e-152 529.00
IUUC-Tni-120843 Tetraodon nigroviridis 68.66 0.00e+00 668.00
IUUC-Tur-126643 Triticum urartu 31.13 3.00e-19 89.00
IUUC-Tbe-127707 Tupaia belangeri 70.72 0.00e+00 655.00
IUUC-Ttr-128893 Tursiops truncatus 72.15 0.00e+00 676.00
IUUC-Vpa-130060 Vicugna pacos 71.58 0.00e+00 676.00
IUUC-Xtr-132322 Xenopus tropicalis 71.58 0.00e+00 677.00
IUUC-Xma-134012 Xiphophorus maculatus 71.37 0.00e+00 684.00
Created Date 25-Jun-2017

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