iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033613

UUCD1 version

UUC-EqC-00946

Ensembl Protein ID

ENSECAP00000009225.1

UniProt Accession

F7AQB2; F7AQB2_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBE2E1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000011371.1	ENSECAT00000011758.1	ENSECAP00000009225.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.80e-50	169.4	51	186

Active Site

Position(s)	Description	Evidence
131	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++++ dpp+++sa+p+ + +++ew+ +ilGp++++YeggvF l+i+f+++YPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 51   RIQKELADITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 136
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 137  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQ 186
           *********************************************99985 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSDDDSRAST SSSSSSSSNQ QTEKETNTPK KKESKVSMSK SSKLLSTSAK RIQKELADIT 60
LDPPPNCSAG PKGDNIYEWR STILGPPGSV YEGGVFFLDI TFTPEYPFKP PKVTFRTRIY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAGCCATT GCCTGTTTAA TAGTTGCTGT TGCTGCACTT CCGCTTCTCT CCCAGCGAGA 60
GAGAGACACG AGTGGCCAGG CCCAGCCGCA GCCGCAGCAG CAGCCGCCGC GGCGTAGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0033523--P:histone H2B ubiquitination
GO:0010390--P:histone monoubiquitination
GO:0032020--P:ISG15-protein conjugation
GO:0070936--P:protein K48-linked ubiquitination

KEGG

ecb:100060214

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004207	Anas platyrhynchos	98.86	1.00e-92	331.00
IUUC-Aca-005103	Anolis carolinensis	98.86	8.00e-93	332.00
IUUC-Cho-024986	Choloepus hoffmanni	76.27	1.00e-74	271.00
IUUC-Dno-029441	Dasypus novemcinctus	100.00	4.00e-75	272.00
IUUC-Dor-030450	Dipodomys ordii	100.00	4.00e-64	235.00
IUUC-Ete-032397	Echinops telfairi	97.71	1.00e-89	321.00
IUUC-Fca-035467	Felis catus	99.37	3.00e-93	333.00
IUUC-Fal-036907	Ficedula albicollis	98.86	8.00e-93	332.00
IUUC-Gga-040403	Gallus gallus	98.86	8.00e-93	332.00
IUUC-Itr-048197	Ictidomys tridecemlineatus	100.00	4.00e-75	272.00
IUUC-Meu-056590	Macropus eugenii	100.00	4.00e-85	305.00
IUUC-Mdo-062348	Monodelphis domestica	99.30	5.00e-84	303.00
IUUC-Mmu-063297	Mus musculus	98.29	5.00e-102	362.00
IUUC-Mpu-065698	Mustela putorius furo	98.86	6.00e-103	365.00
IUUC-Oan-073006	Ornithorhynchus anatinus	100.00	5.00e-75	272.00
IUUC-Ola-086636	Oryzias latipes	96.50	3.00e-81	294.00
IUUC-Oar-089803	Ovis aries	98.86	6.00e-103	365.00
IUUC-Pma-094642	Petromyzon marinus	95.24	4.00e-70	256.00
IUUC-Pfo-096966	Poecilia formosa	96.50	3.00e-81	293.00
IUUC-Rno-105518	Rattus norvegicus	97.69	6.00e-100	355.00
IUUC-Sha-106897	Sarcophilus harrisii	100.00	1.00e-85	308.00
IUUC-Ssc-116298	Sus scrofa	100.00	7.00e-84	301.00
IUUC-Tgu-116958	Taeniopygia guttata	100.00	2.00e-89	320.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence