iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000006351.3	ENSMMUT00000075197.1	ENSMMUP00000049522.1
ENSMMUG00000006351.3	ENSMMUT00000008911.3	ENSMMUP00000008380.2
ENSMMUG00000006351.3	ENSMMUT00000008910.3	ENSMMUP00000008379.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.10e-44	151.8	49	169

Active Site

Position(s)	Description	Evidence
114	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 16   gisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvlls 104
             sa+p+ + +++ew+ +ilGp++++YeggvF l+i+f+++YPfkPPkv+f t+i+h+n++++G +Cl+ilk  ++Wspal++++vlls
   Q: 49   AKSAGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILK--DNWSPALTISKVLLS 134
           447889999.9************************************************************9..*************** PP
   S: 105  iqsllaepnpesplneeaaellkknreeykkkvre 139
           i+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 135  ICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQ 169
           ******************************99985 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSDDDSRAST SSSSSSSSNQ QTEKETNTPK KKESKVSMSK NSKLLSTSAK SAGPKGDNIY 60
EWRSTILGPP GSVYEGGVFF LDITFTPEYP FKPPKVTFRT RIYHCNINSQ GVICLDILKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCGCCTCCC GGGCTACTCC CTCCCTGCCC AGCGGAGAGC CCCGGGGGGC GAGGGAGGGG 60
CCGCTCTCCT AGCTCCAGAC CGTTTTCCCA CAGCGTTCCC CACTTGGGGC CAAAAATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0033523--P:histone H2B ubiquitination
GO:0010390--P:histone monoubiquitination
GO:0032020--P:ISG15-protein conjugation
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dno-029441	Dasypus novemcinctus	100.00	2.00e-75	273.00
IUUC-Eeu-034691	Erinaceus europaeus	87.43	6.00e-87	312.00
IUUC-Itr-048197	Ictidomys tridecemlineatus	100.00	2.00e-75	273.00
IUUC-Oan-073006	Ornithorhynchus anatinus	99.21	3.00e-75	273.00
IUUC-Pca-100912	Procavia capensis	100.00	8.00e-75	271.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence