iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-087952

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03153612

Gene Name

CBLC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000006844.2	ENSOGAT00000006846.2	ENSOGAP00000006126.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.60e-07	30.6	351	390

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+ + +Cl +w     + s +++CP Cr
   Q: 351  CKICAENSKD-VRIEPCGHLLCSHCLAAW-----QHSDSQTCPFCR 390
           99********.******************.....6889999****8 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAAAAARQGR QWEEPHTLGR AVRLLQRLQE QCGDPRLTMS PPRLRDVLPR TAQLLREVAN 60
SRRAGGGGEP EGPGGSGDFL VIFLANLEAK SRQVAALLPP RGRKGANDEL FREGSRLRRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGCAG CCGCGGCCCG ACAGGGGCGA CAGTGGGAAG AGCCCCACAC CCTGGGGCGG 60
GCGGTGAGGC TGCTGCAGCG CCTGCAAGAG CAATGCGGGG ACCCCCGGCT GACCATGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0043407--P:negative regulation of MAP kinase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	82.67	0.00e+00	640.00
IUUC-Bta-012705	Bos taurus	81.24	0.00e+00	656.00
IUUC-Cja-019179	Callithrix jacchus	80.43	0.00e+00	709.00
IUUC-Cfa-020593	Canis familiaris	79.95	0.00e+00	645.00
IUUC-Cpo-021289	Cavia porcellus	77.22	1.00e-176	612.00
IUUC-Csa-023966	Chlorocebus sabaeus	81.92	0.00e+00	663.00
IUUC-Dor-030246	Dipodomys ordii	78.16	1.00e-126	446.00
IUUC-Eca-033921	Equus caballus	74.34	2.00e-156	545.00
IUUC-Fca-035747	Felis catus	67.13	3.00e-161	561.00
IUUC-Ggo-044622	Gorilla gorilla	83.66	7.00e-165	572.00
IUUC-Hsa-045735	Homo sapiens	84.05	0.00e+00	724.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	84.94	2.00e-176	611.00
IUUC-Laf-053983	Loxodonta africana	81.55	0.00e+00	675.00
IUUC-Mmr-061310	Microcebus murinus	84.13	0.00e+00	693.00
IUUC-Mmu-064155	Mus musculus	75.46	0.00e+00	652.00
IUUC-Mpu-066655	Mustela putorius furo	82.38	0.00e+00	660.00
IUUC-Mlu-067929	Myotis lucifugus	84.44	4.00e-154	536.00
IUUC-Nle-070065	Nomascus leucogenys	70.47	3.00e-166	577.00
IUUC-Ocu-074049	Oryctolagus cuniculus	76.01	6.00e-135	473.00
IUUC-Oar-089382	Ovis aries	78.22	0.00e+00	635.00
IUUC-Ptr-090579	Pan troglodytes	70.88	2.00e-133	468.00
IUUC-Pan-092075	Papio anubis	80.82	0.00e+00	670.00
IUUC-Pab-098100	Pongo abelii	74.78	0.00e+00	626.00
IUUC-Pca-100830	Procavia capensis	77.78	1.00e-108	386.00
IUUC-Pva-102714	Pteropus vampyrus	76.98	8.00e-164	570.00
IUUC-Rno-105348	Rattus norvegicus	75.86	0.00e+00	653.00
IUUC-Sha-107138	Sarcophilus harrisii	71.28	5.00e-124	437.00
IUUC-Ssc-116424	Sus scrofa	83.41	0.00e+00	691.00
IUUC-Ttr-128807	Tursiops truncatus	85.06	2.00e-138	484.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence