iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096356

Ensembl Protein ID

ENSPFOP00000014569.2

UniProt Accession

A0A087Y966; A0A087Y966_POEFO

Genbank Protein ID

ENSPFOP00000014569

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01000968

Gene Name

HECTD4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000013830.2	ENSPFOT00000014591.2	ENSPFOP00000014569.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-76	258.7	4091	4451

Active Site

Position(s)	Description	Evidence
4425	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglf.......lysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           d ++ ++++f+gEe+++++G++r+fl++++kelq++ l+l+        + +++k+ l+p p s+     +++l +f+G+llg+a++
   Q: 4091 DPTYAFNIRFTGEEVHGTSGSFRHFLWQVCKELQSSALSLLlpcpsaaANRNKGKYILTPCPISY----AEEQLLHFFGQLLGIAIR 4173
           5667788**********************************999887767777999999999999....689*************** PP
   S: 84   dgrlldlplsksfyklllgkklsl.edleevdpelykslkeikena.esdieelgldltfsvseei...............lgetke 153
            + +l+l+l  sf+k l+g++l+  +dl+e d  +y+++k+  +   es++e+l+++++++ ++ +                 + +e
   Q: 4174 ADVPLPLDLLGSFWKGLVGEPLDPeQDLQEADVLTYNYVKKFANVTdESELEALCAEISSQHHSGEspespsrpcctftyfTMTGEE 4260
           ************************9*************77766554378999999999998666668999********976556667 PP
   S: 154  eeLkpgGenipVtneNkeeYvklvveyrlke.gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggy 239
           +eL++gG++  V +eNk+ Y ++v ++rl+e +  e+++a+r+G+ ++ip++ll+++++ e+el +cG ++i++e lk++t+y+ g+
   Q: 4261 VELCQGGRSLTVSWENKDVYARAVRSLRLRElENVECMTAVRAGLGSIIPMQLLTMLSPLEIELRTCGLPYINLEFLKAHTMYQVGL 4347
           77*****************************99****************************************************** PP
   S: 240  tedspaiqwFwevleefsseerkafLqFvTgssrlPl......gGfaelk....prlfvirk...dasddrlPssnTCfnyLkLPeY 313
           +e++++i++Fw +le+f++ee ++f++F+++++r+P+      gG ++ +    p+++  ++    + d+r+++++TC+++ kLP+Y
   Q: 4348 METDQHIEFFWTALEMFTQEELCKFIKFACNQERIPFtcpckdGGPDTAHvppyPMKIAPPDgaaGQPDSRYIRVETCMFMVKLPQY 4434
           *******************************************9999999998888888888*955666****************** PP
   S: 314  sskeilkekLlyAieet 330
           +s +++ ekL+yAi+++
   Q: 4435 TSLDVMLEKLRYAIHYR 4451
           **************986 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

LPLSASLSEE RVMGSGAVDS SQWLSVKEET IFLHDGLIRV TDLAELPSEI GVSEQGDTEQ 60
EILTFETKNP VELAERLRAV CGNQSNAYAR LLEYRLNALR GLWAAQRQLA LEEQQDREGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCCTCTTT CGGCATCACT GTCGGAGGAG AGAGTGATGG GCTCCGGGGC TGTGGACTCG 60
TCCCAGTGGC TTTCGGTGAA GGAGGAGACG ATATTTCTCC ATGACGGACT CATACGGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002256	Ailuropoda melanoleuca	82.61	0.00e+00	4561.00
IUUC-Apl-004161	Anas platyrhynchos	84.85	0.00e+00	3044.00
IUUC-Aca-005341	Anolis carolinensis	78.55	0.00e+00	5884.00
IUUC-Ame-011574	Astyanax mexicanus	87.95	0.00e+00	5453.00
IUUC-Bta-012514	Bos taurus	75.74	0.00e+00	1604.00
IUUC-Cja-019148	Callithrix jacchus	82.61	0.00e+00	3114.00
IUUC-Cfa-020499	Canis familiaris	83.10	0.00e+00	5006.00
IUUC-Cpo-021894	Cavia porcellus	84.74	0.00e+00	2429.00
IUUC-Csa-023079	Chlorocebus sabaeus	81.77	0.00e+00	6712.00
IUUC-Cho-024415	Choloepus hoffmanni	79.31	0.00e+00	4306.00
IUUC-Dre-027452	Danio rerio	85.30	0.00e+00	5414.00
IUUC-Dno-029595	Dasypus novemcinctus	81.73	0.00e+00	6688.00
IUUC-Dor-030849	Dipodomys ordii	85.86	0.00e+00	1583.00
IUUC-Ete-032563	Echinops telfairi	73.95	0.00e+00	960.00
IUUC-Eca-034202	Equus caballus	82.58	0.00e+00	4552.00
IUUC-Eeu-035175	Erinaceus europaeus	86.26	0.00e+00	979.00
IUUC-Fca-036295	Felis catus	84.47	0.00e+00	4493.00
IUUC-Fal-037003	Ficedula albicollis	80.77	0.00e+00	5875.00
IUUC-Gmo-038579	Gadus morhua	93.30	0.00e+00	3108.00
IUUC-Gga-040961	Gallus gallus	83.73	0.00e+00	5274.00
IUUC-Gac-041899	Gasterosteus aculeatus	94.72	0.00e+00	3196.00
IUUC-Ggo-045099	Gorilla gorilla	83.02	0.00e+00	5467.00
IUUC-Hsa-046331	Homo sapiens	81.46	0.00e+00	6578.00
IUUC-Itr-048190	Ictidomys tridecemlineatus	79.65	0.00e+00	1609.00
IUUC-Lch-049923	Latimeria chalumnae	76.96	0.00e+00	2391.00
IUUC-Loc-052630	Lepisosteus oculatus	88.47	0.00e+00	4182.00
IUUC-Laf-053394	Loxodonta africana	83.62	0.00e+00	4834.00
IUUC-Mcc-055763	Macaca mulatta	81.37	0.00e+00	6734.00
IUUC-Meu-056039	Macropus eugenii	77.34	0.00e+00	4459.00
IUUC-Mga-059500	Meleagris gallopavo	82.27	0.00e+00	4593.00
IUUC-Mmr-060868	Microcebus murinus	78.53	0.00e+00	6530.00
IUUC-Mdo-062772	Monodelphis domestica	82.32	0.00e+00	5201.00
IUUC-Mmu-063606	Mus musculus	83.07	0.00e+00	5239.00
IUUC-Mpu-065860	Mustela putorius furo	80.27	0.00e+00	4440.00
IUUC-Mlu-067376	Myotis lucifugus	82.72	0.00e+00	4574.00
IUUC-Nle-069693	Nomascus leucogenys	79.46	0.00e+00	6370.00
IUUC-Opr-071065	Ochotona princeps	81.59	0.00e+00	1004.00
IUUC-Ont-072470	Oreochromis niloticus	94.13	0.00e+00	5185.00
IUUC-Oan-073693	Ornithorhynchus anatinus	84.83	0.00e+00	3030.00
IUUC-Ocu-074032	Oryctolagus cuniculus	80.52	0.00e+00	6749.00
IUUC-Ola-087433	Oryzias latipes	94.15	0.00e+00	1767.00
IUUC-Oga-088546	Otolemur garnettii	84.32	0.00e+00	4362.00
IUUC-Oar-089643	Ovis aries	82.76	0.00e+00	696.00
IUUC-Ptr-090504	Pan troglodytes	81.18	0.00e+00	6151.00
IUUC-Pan-092543	Papio anubis	81.77	0.00e+00	6715.00
IUUC-Psi-093952	Pelodiscus sinensis	80.44	0.00e+00	4424.00
IUUC-Pab-098240	Pongo abelii	81.24	0.00e+00	6769.00
IUUC-Pca-100994	Procavia capensis	83.98	0.00e+00	2553.00
IUUC-Pva-102263	Pteropus vampyrus	81.98	0.00e+00	4497.00
IUUC-Rno-104888	Rattus norvegicus	83.60	0.00e+00	4838.00
IUUC-Sha-106944	Sarcophilus harrisii	81.48	0.00e+00	4558.00
IUUC-Sar-113556	Sorex araneus	80.65	0.00e+00	909.00
IUUC-Ssc-116187	Sus scrofa	86.16	0.00e+00	2907.00
IUUC-Tgu-116655	Taeniopygia guttata	85.26	0.00e+00	3055.00
IUUC-Tru-118093	Takifugu rubripes	93.88	0.00e+00	3300.00
IUUC-Tni-119739	Tetraodon nigroviridis	92.94	0.00e+00	1766.00
IUUC-Tbe-127962	Tupaia belangeri	65.98	0.00e+00	923.00
IUUC-Ttr-128819	Tursiops truncatus	75.30	0.00e+00	2409.00
IUUC-Vpa-130482	Vicugna pacos	81.23	0.00e+00	3833.00
IUUC-Xtr-132222	Xenopus tropicalis	79.80	0.00e+00	6036.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence