iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012538

UUCD1 version

UUC-BoT-00975

Ensembl Protein ID

ENSBTAP00000000956.5

UniProt Accession

Q58D00; Q58DP3; FBXW2_BOVIN

Genbank Protein ID

AAX46401.1; AAX46644.1; AAI20225.1

Protein Name

F-box/WD repeat-containing protein 2; F-box and WD-40 domain-containing protein 2

Genbank Nucleotide ID

BT021554; BT021797; BC120224

Gene Name

FBXW2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000000712.5	ENSBTAT00000000956.5	ENSBTAP00000000956.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-23	80.7	224	261

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHt+ v+++++ ++ ++lvsGs D t+kvW l+ g++l
   Q: 224  GHTGAVFSVDYnDElDILVSGSADFTVKVWALSAGTCL 261
           8**********555999*****************9997 PP

Organism

Bos taurus

Functional Description
(View)

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Protein Sequence
(Fasta)

MERKDFETWL DNISVTFLSL TDLQKNETLD HLISLSGAVQ LRHLSNNLET LLKRDFLKLL 60
PLELSFYLLK WLDPQTLLTC CLVSKQWNKV ISACTEVWQT ACKSLGWQID DSVQDALHWK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGCTGCGG ACCCGGAGCG GCGGCCGCAG GTCCAGGTCT GTGTACTAGG CGGGGCCGGG 60
TCGCGGAGGG GGTTGTTTGG CGCCCGCGCC TCTGCTGACC CGCCGCGCCT CGGGCTGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

KEGG

bta:767863

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001726	Ailuropoda melanoleuca	99.56	0.00e+00	888.00
IUUC-Apl-003329	Anas platyrhynchos	94.05	0.00e+00	851.00
IUUC-Aca-004491	Anolis carolinensis	91.78	7.00e-154	536.00
IUUC-Ame-011713	Astyanax mexicanus	80.44	0.00e+00	739.00
IUUC-Cja-018833	Callithrix jacchus	99.56	0.00e+00	888.00
IUUC-Cfa-020233	Canis familiaris	99.56	0.00e+00	888.00
IUUC-Cpo-021662	Cavia porcellus	98.68	0.00e+00	885.00
IUUC-Csa-023818	Chlorocebus sabaeus	99.56	0.00e+00	888.00
IUUC-Cin-025489	Ciona intestinalis	31.65	2.00e-42	165.00
IUUC-Dre-028713	Danio rerio	79.78	0.00e+00	722.00
IUUC-Dno-029701	Dasypus novemcinctus	98.68	0.00e+00	879.00
IUUC-Dor-030944	Dipodomys ordii	98.68	0.00e+00	884.00
IUUC-Ete-033151	Echinops telfairi	97.36	0.00e+00	859.00
IUUC-Eca-033984	Equus caballus	99.12	0.00e+00	886.00
IUUC-Eeu-034517	Erinaceus europaeus	83.10	1.00e-137	482.00
IUUC-Fca-035678	Felis catus	99.56	0.00e+00	888.00
IUUC-Fal-036805	Ficedula albicollis	94.27	0.00e+00	853.00
IUUC-Gmo-039517	Gadus morhua	78.41	0.00e+00	725.00
IUUC-Gga-040872	Gallus gallus	93.39	0.00e+00	848.00
IUUC-Gac-042579	Gasterosteus aculeatus	76.87	0.00e+00	694.00
IUUC-Ggo-045157	Gorilla gorilla	99.34	0.00e+00	885.00
IUUC-Hsa-045668	Homo sapiens	99.56	0.00e+00	888.00
IUUC-Itr-048301	Ictidomys tridecemlineatus	99.12	0.00e+00	885.00
IUUC-Lch-049887	Latimeria chalumnae	87.00	0.00e+00	786.00
IUUC-Loc-052187	Lepisosteus oculatus	83.26	0.00e+00	754.00
IUUC-Laf-053958	Loxodonta africana	99.12	0.00e+00	884.00
IUUC-Mcc-054903	Macaca mulatta	99.34	0.00e+00	887.00
IUUC-Meu-056564	Macropus eugenii	94.27	0.00e+00	839.00
IUUC-Mga-060169	Meleagris gallopavo	93.83	0.00e+00	851.00
IUUC-Mdo-061997	Monodelphis domestica	96.48	0.00e+00	869.00
IUUC-Mmu-063709	Mus musculus	98.23	0.00e+00	877.00
IUUC-Mpu-066578	Mustela putorius furo	99.56	0.00e+00	888.00
IUUC-Mlu-067555	Myotis lucifugus	98.90	0.00e+00	885.00
IUUC-Nle-069408	Nomascus leucogenys	99.34	0.00e+00	887.00
IUUC-Opr-070771	Ochotona princeps	76.33	4.00e-158	550.00
IUUC-Ont-072597	Oreochromis niloticus	81.50	0.00e+00	719.00
IUUC-Oan-072768	Ornithorhynchus anatinus	98.25	2.00e-120	424.00
IUUC-Ocu-074312	Oryctolagus cuniculus	99.56	0.00e+00	888.00
IUUC-Ola-086660	Oryzias latipes	81.28	0.00e+00	714.00
IUUC-Oga-088471	Otolemur garnettii	88.48	0.00e+00	769.00
IUUC-Oar-089744	Ovis aries	98.90	0.00e+00	877.00
IUUC-Ptr-090977	Pan troglodytes	99.56	0.00e+00	888.00
IUUC-Pan-092850	Papio anubis	99.34	0.00e+00	888.00
IUUC-Psi-093875	Pelodiscus sinensis	93.17	0.00e+00	841.00
IUUC-Pma-094257	Petromyzon marinus	69.30	0.00e+00	627.00
IUUC-Pfo-096359	Poecilia formosa	81.50	0.00e+00	719.00
IUUC-Pab-097730	Pongo abelii	99.34	0.00e+00	887.00
IUUC-Pca-101089	Procavia capensis	100.00	5.00e-81	294.00
IUUC-Pva-102555	Pteropus vampyrus	99.34	0.00e+00	887.00
IUUC-Rno-104837	Rattus norvegicus	98.24	0.00e+00	879.00
IUUC-Sha-107582	Sarcophilus harrisii	96.48	0.00e+00	865.00
IUUC-Sar-112994	Sorex araneus	76.82	4.00e-138	484.00
IUUC-Ssc-115254	Sus scrofa	99.56	0.00e+00	886.00
IUUC-Tgu-117122	Taeniopygia guttata	94.05	0.00e+00	853.00
IUUC-Tru-118198	Takifugu rubripes	81.94	0.00e+00	747.00
IUUC-Tsy-119295	Tarsius syrichta	98.90	0.00e+00	884.00
IUUC-Tni-120193	Tetraodon nigroviridis	80.40	0.00e+00	708.00
IUUC-Tbe-127929	Tupaia belangeri	98.46	0.00e+00	845.00
IUUC-Ttr-128816	Tursiops truncatus	99.56	0.00e+00	888.00
IUUC-Vpa-130198	Vicugna pacos	99.72	0.00e+00	691.00
IUUC-Xtr-132551	Xenopus tropicalis	88.33	0.00e+00	798.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence