iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074755

Ensembl Protein ID

ENSOCUP00000003905.3

UniProt Accession

G1SLZ2; G1SLZ2_RABIT

Genbank Protein ID

ENSOCUP00000003905

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02053833

Gene Name

JADE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000004521.3	ENSOCUT00000004522.3	ENSOCUP00000003905.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-10	41.6	234	281

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek.slveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +vC vC++++ ++  ++v C+kC+ ++H+aC ++    ++p+ + w C+ C 
   Q: 234  VVCDVCQSPDGEDGnEMVFCDKCNICVHQACYGIL---KVPEGS-WLCRTCA 281
           69******99887569*******************...*****8.******5 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MEAGRKAFCF QKILSSPVFY LGCLLFPGEI MKRGRLPSSS EDSDDNGSLS TTWSQNSRSQ 60
HRRSSCSRHE DRKPSEVFRT DLITAMKLHD SYQLNPDEYY VLADPWRQEW EKGVQVPVSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAGACCAA GCACTTGACC ATCTTCTACT GCTTTCCCAG GCCATAGCAG AGAGCTGGAT 60
GGGAAGTAGA GCAACCGGGA CTTGAACTGG CACCCATATG GGATGCTGGC ACTGCAGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR019542--Enhancer_polycomb-like_N
IPR034732--EPHD
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF10513--EPL1

SMART

SM00249--PHD

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0005829--C:cytosol
GO:0000123--C:histone acetyltransferase complex
GO:0005886--C:plasma membrane
GO:0001105--F:RNA polymerase II transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0043966--P:histone H3 acetylation
GO:0043983--P:histone H4-K12 acetylation
GO:0043981--P:histone H4-K5 acetylation
GO:0043982--P:histone H4-K8 acetylation
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000134--P:negative regulation of G1/S transition of mitotic cell cycle

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001854	Ailuropoda melanoleuca	95.76	0.00e+00	1628.00
IUUC-Apl-003904	Anas platyrhynchos	81.36	0.00e+00	1319.00
IUUC-Aca-004650	Anolis carolinensis	77.40	0.00e+00	1339.00
IUUC-Ame-011188	Astyanax mexicanus	36.46	2.00e-30	127.00
IUUC-Bta-013212	Bos taurus	95.04	0.00e+00	1548.00
IUUC-Cel-018258	Caenorhabditis elegans	28.96	7.00e-16	79.00
IUUC-Cja-019342	Callithrix jacchus	96.36	0.00e+00	1603.00
IUUC-Cfa-021159	Canis familiaris	94.32	0.00e+00	1599.00
IUUC-Cpo-022179	Cavia porcellus	95.85	0.00e+00	1610.00
IUUC-Csa-024123	Chlorocebus sabaeus	96.61	0.00e+00	1605.00
IUUC-Cin-025300	Ciona intestinalis	28.88	3.00e-13	70.10
IUUC-Dre-028450	Danio rerio	35.36	3.00e-27	117.00
IUUC-Dno-028951	Dasypus novemcinctus	95.50	0.00e+00	1621.00
IUUC-Dor-030376	Dipodomys ordii	91.80	7.00e-166	577.00
IUUC-Dme-031650	Drosophila melanogaster	37.57	7.00e-27	116.00
IUUC-Ete-032829	Echinops telfairi	28.80	2.00e-17	84.30
IUUC-Eca-033527	Equus caballus	36.41	1.00e-30	128.00
IUUC-Eeu-035092	Erinaceus europaeus	37.21	8.00e-21	95.90
IUUC-Fca-035825	Felis catus	95.73	0.00e+00	1663.00
IUUC-Fal-037191	Ficedula albicollis	81.32	0.00e+00	1381.00
IUUC-Gmo-038924	Gadus morhua	34.95	6.00e-29	122.00
IUUC-Gga-040453	Gallus gallus	82.62	0.00e+00	1106.00
IUUC-Gac-041895	Gasterosteus aculeatus	34.03	2.00e-28	121.00
IUUC-Ggo-044730	Gorilla gorilla	96.36	0.00e+00	1598.00
IUUC-Hsa-045954	Homo sapiens	96.61	0.00e+00	1602.00
IUUC-Itr-047942	Ictidomys tridecemlineatus	93.58	0.00e+00	1503.00
IUUC-Lch-050370	Latimeria chalumnae	66.67	0.00e+00	1042.00
IUUC-Loc-052824	Lepisosteus oculatus	59.75	0.00e+00	975.00
IUUC-Laf-053741	Loxodonta africana	95.62	0.00e+00	1608.00
IUUC-Mcc-055206	Macaca mulatta	96.64	0.00e+00	1624.00
IUUC-Meu-055951	Macropus eugenii	77.22	0.00e+00	765.00
IUUC-Mga-059286	Meleagris gallopavo	79.78	0.00e+00	1263.00
IUUC-Mvi-060566	Microbotryum violaceum	32.95	5.00e-14	74.30
IUUC-Mmr-061461	Microcebus murinus	95.52	0.00e+00	1579.00
IUUC-Mdo-062145	Monodelphis domestica	82.04	0.00e+00	1359.00
IUUC-Mmu-063766	Mus musculus	90.45	0.00e+00	1501.00
IUUC-Mpu-066859	Mustela putorius furo	94.35	0.00e+00	1518.00
IUUC-Mlu-068114	Myotis lucifugus	89.50	0.00e+00	1285.00
IUUC-Nle-069678	Nomascus leucogenys	96.48	0.00e+00	1602.00
IUUC-Opr-070669	Ochotona princeps	28.80	5.00e-17	83.20
IUUC-Ont-072674	Oreochromis niloticus	68.31	0.00e+00	732.00
IUUC-Ola-086618	Oryzias latipes	53.33	0.00e+00	726.00
IUUC-Olu-087752	Ostreococcus lucimarinus	46.94	1.00e-38	151.00
IUUC-Oga-089141	Otolemur garnettii	96.48	0.00e+00	1596.00
IUUC-Oar-089329	Ovis aries	95.16	0.00e+00	1588.00
IUUC-Ptr-091632	Pan troglodytes	96.61	0.00e+00	1602.00
IUUC-Pan-091906	Papio anubis	96.73	0.00e+00	1607.00
IUUC-Psi-093869	Pelodiscus sinensis	36.41	1.00e-30	128.00
IUUC-Pma-094703	Petromyzon marinus	36.07	5.00e-28	119.00
IUUC-Pfo-096495	Poecilia formosa	51.16	0.00e+00	739.00
IUUC-Pab-098033	Pongo abelii	96.36	0.00e+00	1592.00
IUUC-Pca-100931	Procavia capensis	36.08	4.00e-13	70.10
IUUC-Pva-102586	Pteropus vampyrus	91.85	0.00e+00	1460.00
IUUC-Rno-105725	Rattus norvegicus	36.41	1.00e-30	128.00
IUUC-Sha-106818	Sarcophilus harrisii	87.30	0.00e+00	1135.00
IUUC-Ssl-108594	Sclerotinia sclerotiorum	40.54	2.00e-07	52.40
IUUC-Smo-109236	Selaginella moellendorffii	38.21	2.00e-39	158.00
IUUC-Sar-113710	Sorex araneus	38.39	3.00e-20	94.00
IUUC-Sre-115128	Sporisorium reilianum	34.18	1.00e-11	65.50
IUUC-Ssc-116244	Sus scrofa	95.85	0.00e+00	1618.00
IUUC-Tgu-117051	Taeniopygia guttata	80.38	0.00e+00	1341.00
IUUC-Tru-118032	Takifugu rubripes	67.72	0.00e+00	658.00
IUUC-Tsy-118886	Tarsius syrichta	36.41	1.00e-30	128.00
IUUC-Tni-120429	Tetraodon nigroviridis	67.21	0.00e+00	716.00
IUUC-Tre-122041	Trichoderma reesei	42.86	7.00e-14	73.90
IUUC-Ttr-129299	Tursiops truncatus	95.02	0.00e+00	1618.00
IUUC-Uma-129405	Ustilago maydis	32.65	1.00e-11	65.90
IUUC-Vpa-130327	Vicugna pacos	36.41	8.00e-31	129.00
IUUC-Xtr-132813	Xenopus tropicalis	66.67	0.00e+00	1053.00
IUUC-Xma-133556	Xiphophorus maculatus	53.02	0.00e+00	760.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence