iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015523

Ensembl Protein ID

Bo00895s040.1

UniProt Accession

A0A0D2ZS17; A0A0D2ZS17_BRAOL

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo00895s040	Bo00895s040.1	Bo00895s040.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	36.51	4.00e-38	155.00	IUUC-Dme-031755

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Brassica oleracea

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MAPGGSALKE VLESNSTGMD YEVKTTKVEV NNSNNSKSTK SGGAGTGKYG MHSNNGVYEL 60
LECPVCTNLM YPPIHQCPNG HTLCSNCKAR VQNTCPTCRY ELGNIRCLAL EKVAESLEVP 120

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Nucleotide Sequence
(Fasta)

ATGGCTCCTG GAGGCAGTGC TTTGAAAGAA GTCCTTGAAT CTAACTCAAC GGGAATGGAT 60
TACGAGGTTA AAACGACCAA AGTGGAAGTT AATAATAGTA ACAACAGCAA ATCTACAAAG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	68.05	3.00e-127	447.00
IUUC-Atr-003118	Amborella trichopoda	72.44	6.00e-133	466.00
IUUC-Aca-005014	Anolis carolinensis	35.11	2.00e-42	165.00
IUUC-Ame-011196	Astyanax mexicanus	34.06	6.00e-43	167.00
IUUC-Cfa-020642	Canis familiaris	35.11	1.00e-42	166.00
IUUC-Cpo-022348	Cavia porcellus	36.36	3.00e-42	165.00
IUUC-Dre-028041	Danio rerio	34.06	9.00e-43	167.00
IUUC-Dme-031755	Drosophila melanogaster	35.23	2.00e-40	159.00
IUUC-Ete-032423	Echinops telfairi	35.00	8.00e-42	164.00
IUUC-Eeu-035314	Erinaceus europaeus	33.57	4.00e-42	164.00
IUUC-Hvu-047574	Hordeum vulgare	68.25	8.00e-128	449.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	36.36	3.00e-42	165.00
IUUC-Lch-049504	Latimeria chalumnae	36.36	3.00e-42	165.00
IUUC-Lpe-050879	Leersia perrieri	68.49	2.00e-127	448.00
IUUC-Loc-052191	Lepisosteus oculatus	34.06	6.00e-43	167.00
IUUC-Mmr-060794	Microcebus murinus	36.36	3.00e-42	165.00
IUUC-Mlu-067207	Myotis lucifugus	35.11	1.00e-42	166.00
IUUC-Ome-081318	Oryza meridionalis	68.49	3.00e-127	447.00
IUUC-Opu-084065	Oryza punctata	68.17	6.00e-127	446.00
IUUC-Oga-088399	Otolemur garnettii	36.36	3.00e-42	165.00
IUUC-Ptr-090692	Pan troglodytes	36.36	5.00e-42	164.00
IUUC-Pma-094387	Petromyzon marinus	33.94	2.00e-42	166.00
IUUC-Ppa-095212	Physcomitrella patens	86.05	2.00e-137	481.00
IUUC-Pop-099563	Populus trichocarpa	69.77	2.00e-135	474.00
IUUC-Smo-109412	Selaginella moellendorffii	74.20	9.00e-140	489.00
IUUC-Stu-112714	Solanum tuberosum	70.97	4.00e-136	477.00
IUUC-Tae-123647	Triticum aestivum	68.05	3.00e-127	447.00
IUUC-Tbe-127330	Tupaia belangeri	29.13	7.00e-07	47.00
IUUC-Ttr-129166	Tursiops truncatus	35.83	6.00e-40	157.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence