iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006660

UUCD1 version

UUC-ArT-01620

Ensembl Protein ID

AT1G64230.5

UniProt Accession

Q94F47; Q9SH72; UBC28_ARATH

Genbank Protein ID

AAM11574.1; AAY44867.1; AAF24583.1; AEE34212.1; AEE34213.1; AAK60309.1; AAM91500.1

Protein Name

Ubiquitin-conjugating enzyme E2 28; E2 ubiquitin-conjugating enzyme 28; Ubiquitin carrier protein 28

Genbank Nucleotide ID

AF480945; DQ027041; AC007764; CP002684; CP002684; AF385718; AY133670

Gene Name

UBC28; UBC9A; At1g64230; F22C12.2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G64230	AT1G64230.5	AT1G64230.5
AT1G64230	AT1G64230.2	AT1G64230.2
AT1G64230	AT1G64230.3	AT1G64230.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	16339806

Classification

Family	E-value	Score	Start	End
E2/UBC	4.40e-52	176.4	61	181

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 15   egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvllsiqsllaep 112
           +++ + pv e d+++w+++i+Gp+d+pY ggvF ++i+fp+dYPfkPPkv f tk+fhPnv++nG++Cl+ilk  e+Wspal++++vllsi+sll++p
   Q: 61   AHVLLCPVAE-DMFHWQATIMGPSDSPYSGGVFLVTIHFPPDYPFKPPKVAFRTKVFHPNVNSNGSICLDILK--EQWSPALTISKVLLSICSLLTDP 155
           5566677888.9************************************************************9..*********************** PP
   S: 113  npesplneeaaellkknreeykkkvr 138
           np++pl  e+a+++k++r++y++++r
   Q: 156  NPDDPLVPEIAHMYKTDRAKYESTAR 181
           **********************9987 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.

Protein Sequence
(Fasta)

MASKRILKEL KDLQKDPPTS CSAVDNASKL LVLIELEDCC RRFSNCSCIL LLEKSQDIAM 60
AHVLLCPVAE DMFHWQATIM GPSDSPYSGG VFLVTIHFPP DYPFKPPKVA FRTKVFHPNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAATAAAAT TTCTCTCTCT TTGTTTATTC GTTAGGTCTC AAAGGCTCTC TCTGTCTCTT 60
TCTCAAAAAT CATCTGCAGG AAGTGAATCG TCAAAACCGA GTTTGGAGGA TCTGTCTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0016740--F:transferase activity
GO:0016567--P:protein ubiquitination

KEGG

ath:AT1G64230

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Stu-112561	Solanum tuberosum	77.37	2.00e-82	297.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence