iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037217

Ensembl Protein ID

ENSFALP00000009876.1

UniProt Accession

U3K4C2; U3K4C2_FICAL

Genbank Protein ID

ENSFALP00000009876

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021631

Gene Name

UBE2D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000009474.1	ENSFALT00000009916.1	ENSFALP00000009876.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.70e-48	163.6	2	109
UBD/UBC-like/UBD_UBC	8.10e-72	239.5	1	112

Active Site

Position(s)	Description	Evidence
55	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 29   ewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvllsiqsllaepnpesp 117
           +w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++Wspal++++vllsi+sll++pnp++p
   Q: 2    HWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQWSPALTISKVLLSICSLLCDPNPDDP 88
           8*********************************************************9..**************************** PP
   S: 118  lneeaaellkknreeykkkvr 138
           l  e+a+++k++re+y++++r
   Q: 89   LVPEIARIYKTDREKYNRIAR 109
           *****************9987 PP

UBD/UBC-like/UBD_UBC

   S: 27   felratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaaltlskvllslcslladaepddpl 115
           f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+alt+skvlls+csll+d++pddpl
   Q: 1    FHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPL 89
           7**************************************************************************************** PP
   S: 116  vaeiariyktdkekykriarewt 138
           v+eiariyktd+eky+riarewt
   Q: 90   VPEIARIYKTDREKYNRIAREWT 112
           **********************8 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

FHWQATIMGP NDSPYQGGVF FLTIHFPTDY PFKPPKVAFT TRIYHPNINS NGSICLDILR 60
SQWSPALTIS KVLLSICSLL CDPNPDDPLV PEIARIYKTD REKYNRIARE WTQKYAM 117

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAAAATGT CTGTTGTGAA TTACTGGTGA CAATGCTGAA ATTTTGCTTC AAAATGAAGA 60
AAAATAGCAT ATTTCAGGTG TATTGTGAGT TACTCAGCTT GTTGAGACTC ATAATAGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dor-030488	Dipodomys ordii	100.00	9.00e-68	249.00
IUUC-Eeu-035113	Erinaceus europaeus	100.00	2.00e-67	246.00
IUUC-Fca-036022	Felis catus	100.00	2.00e-67	246.00
IUUC-Lch-049792	Latimeria chalumnae	97.44	4.00e-66	242.00
IUUC-Ome-081213	Oryza meridionalis	82.91	3.00e-57	213.00
IUUC-Oar-090331	Ovis aries	100.00	2.00e-67	246.00
IUUC-Rno-105628	Rattus norvegicus	100.00	2.00e-67	246.00
IUUC-Tgu-117070	Taeniopygia guttata	100.00	2.00e-67	246.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence