iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036022

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02181257

Gene Name

UBE2D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000022060.1	ENSFCAT00000023760.1	ENSFCAP00000017913.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.00e-49	165.2	1	110
UBD/UBC-like/UBD_UBC	2.20e-72	241.7	1	113

Active Site

Position(s)	Description	Evidence
56	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 27   ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvllsiqsllaepnpe 115
           +++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++Wspal++++vllsi+sll++pnp+
   Q: 1    MFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQWSPALTISKVLLSICSLLCDPNPD 87
           789*********************************************************9..************************** PP
   S: 116  splneeaaellkknreeykkkvr 138
           +pl  e+a+++k++re+y++++r
   Q: 88   DPLVPEIARIYKTDREKYNRIAR 110
           *******************9987 PP

UBD/UBC-like/UBD_UBC

   S: 26   lfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaaltlskvllslcslladaepddp 114
           +f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+alt+skvlls+csll+d++pddp
   Q: 1    MFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDP 89
           89*************************************************************************************** PP
   S: 115  lvaeiariyktdkekykriarewt 138
           lv+eiariyktd+eky+riarewt
   Q: 90   LVPEIARIYKTDREKYNRIAREWT 113
           ***********************8 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MFHWQATIMG PNDSPYQGGV FFLTIHFPTD YPFKPPKVAF TTRIYHPNIN SNGSICLDIL 60
RSQWSPALTI SKVLLSICSL LCDPNPDDPL VPEIARIYKT DREKYNRIAR EWTQKYAM 118

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAGCTAGG AGTCGAGAAG AGTTCCAGAG GGAGACTTGA GTCAGTGATT CCAGTAGGTA 60
TTCTTAAATT AACTAGTGTA ACAGAATACT CAATTAAGAT TTTAATGGTA GGTCTTCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dor-030488	Dipodomys ordii	100.00	8.00e-68	249.00
IUUC-Eeu-035113	Erinaceus europaeus	100.00	2.00e-67	246.00
IUUC-Fal-037217	Ficedula albicollis	100.00	2.00e-67	246.00
IUUC-Lch-049792	Latimeria chalumnae	97.46	7.00e-67	244.00
IUUC-Ome-081213	Oryza meridionalis	83.05	6.00e-58	215.00
IUUC-Oar-090331	Ovis aries	100.00	4.00e-68	249.00
IUUC-Rno-105628	Rattus norvegicus	99.15	1.00e-67	247.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence