iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gma-043967

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ribosome biogenesis protein WDR12 homolog

Genbank Nucleotide ID

CM000846

Gene Name

LOC100811859; GLYMA_13G056900

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GLYMA13G06140	GLYMA13G06140.1	GLYMA13G06140.1
GLYMA13G06140	GLYMA13G06140.2	GLYMA13G06140.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-30	106.0	359	393
UBD/Beta-Prp	1.40e-39	137.7	264	426

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtg 33
           H ++v+++++  ++  +l+s+s+Dg++++WDlrt 
   Q: 359  HMSWVSACKWhdQSwFHLLSASYDGKVMLWDLRTA 393
           99********9744577***************986 PP

UBD/Beta-Prp

   S: 84   gkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl...ktgkllr 173
           g+ + tl gh++ v ++ + + ++++ s+s+d  ir wd+etg+ l +++    +v nc+ + ++g  l+++G+ D ++r+Wd     t   + 
   Q: 264  GEAFTTLVGHTQCVSAVVWPQ-RESIYSASWDHSIRKWDVETGKNLTDLF--CGKVLNCLDIGGEGsTLIAAGGSDPVIRIWDPrkpGTSAPVF 354
           78999***********99988.9***********************7555..5578****************************8666777888 PP
   S: 174  tltgghtdsvyslsfdsng.kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsi 246
           ++++ h + v   ++++++ ++l+s+s+dg+v lwdl+t   +   + h+d v+s + + +++ ++sg++D  +
   Q: 355  QFSS-HMSWVSACKWHDQSwFHLLSASYDGKVMLWDLRTAWPLSVIESHSDKVLSADWW-KSNSVISGGADSKL 426
           8898.************999***************************************.9*********9876 PP

Organism

Glycine max

Functional Description
(View)

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

Protein Sequence
(Fasta)

MNMNEESGEG SARRVQVRFV TKLGEPYKVP TTAIAIPADL ARLGLSSLVN ALLQSNDADH 60
QPEPFDFLID GEFVRMSLEQ FLLAKGISAE RILEIEYARA VAPRKEEDPS LHDDWVSAVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAACTCAGG GGTATTAGTG TAATTTGATC TAAATTCTAA AACCCATGGC AACTGAACTC 60
GCAGGTTGAG AACCGTTAAA CCCTAGCTTC TTCTTCCTCT TCGATTAGCG TCTTCGTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08154--NLE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000460--P:maturation of 5.8S rRNA
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000470--P:maturation of LSU-rRNA
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

KEGG

gmx:100811859

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ath-006669	Arabidopsis thaliana	70.56	0.00e+00	630.00
IUUC-Bdi-014351	Brachypodium distachyon	66.05	2.00e-161	561.00
IUUC-Bol-016514	Brassica oleracea	68.62	9.00e-173	599.00
IUUC-Cel-018569	Caenorhabditis elegans	25.90	7.00e-28	118.00
IUUC-Cin-025789	Ciona intestinalis	30.79	2.00e-52	199.00
IUUC-Hvu-047331	Hordeum vulgare	64.66	2.00e-146	512.00
IUUC-Lpe-051675	Leersia perrieri	63.93	3.00e-166	578.00
IUUC-Loc-052868	Lepisosteus oculatus	35.95	4.00e-66	245.00
IUUC-Mac-065540	Musa acuminata	63.62	1.00e-166	578.00
IUUC-Oni-082507	Oryza nivara	60.96	9.00e-155	539.00
IUUC-Opu-083396	Oryza punctata	63.87	1.00e-164	573.00
IUUC-Oru-085220	Oryza rufipogon	61.19	3.00e-155	541.00
IUUC-Pop-099977	Populus trichocarpa	68.74	0.00e+00	642.00
IUUC-Pyt-104609	Pyrenophora triticirepentis	30.60	1.00e-41	164.00
IUUC-Stu-112778	Solanum tuberosum	70.00	3.00e-174	604.00
IUUC-Tae-123504	Triticum aestivum	64.50	6.00e-168	583.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence