iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001811

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01004280

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000007167.1	ENSAMET00000007892.1	ENSAMEP00000007574.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-42	141.2	235	275
UBD/Beta-Prp	1.90e-54	185.0	189	394

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllk 37
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++
   Q: 235  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCVQ 275
           8***********9644499********************98 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 189  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ-A 276
           567889999*********99***************************************9778************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 277  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 365
           ******************************************95333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++r+W
   Q: 366  HENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           ***************************** PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MCDQTFLVNV FGSCDKCFKQ RALRPVFKKS QQLSYCSMCA EIMNTDYFHK EPARTASISQ 60
AGSMRNLLSL ERAQTRKLNM HQVAERVEAL GQFVMKTRRT LKGHGNKVLC MDWCKDKRRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGATC AGACCTTTCT CGTTAATGTA TTTGGCTCCT GTGACAAATG TTTCAAACAA 60
CGGGCTCTGA GACCAGTTTT CAAGAAATCT CAACAGCTCA GCTACTGTTC AATGTGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003399	Anas platyrhynchos	98.72	0.00e+00	650.00
IUUC-Aca-004861	Anolis carolinensis	86.33	0.00e+00	726.00
IUUC-Ame-011851	Astyanax mexicanus	88.41	0.00e+00	649.00
IUUC-Bta-012438	Bos taurus	91.78	0.00e+00	678.00
IUUC-Cel-018408	Caenorhabditis elegans	63.80	2.00e-133	468.00
IUUC-Cja-019086	Callithrix jacchus	92.62	0.00e+00	761.00
IUUC-Cfa-021255	Canis familiaris	91.86	0.00e+00	738.00
IUUC-Cpo-021398	Cavia porcellus	91.41	0.00e+00	752.00
IUUC-Csa-023776	Chlorocebus sabaeus	92.07	0.00e+00	681.00
IUUC-Cin-025305	Ciona intestinalis	56.42	9.00e-125	439.00
IUUC-Csv-026058	Ciona savignyi	57.42	1.00e-122	432.00
IUUC-Dre-028432	Danio rerio	79.49	0.00e+00	657.00
IUUC-Dno-029958	Dasypus novemcinctus	82.07	1.00e-138	485.00
IUUC-Dor-031013	Dipodomys ordii	99.22	6.00e-153	533.00
IUUC-Dme-031889	Drosophila melanogaster	65.38	1.00e-141	496.00
IUUC-Eca-033977	Equus caballus	91.39	0.00e+00	750.00
IUUC-Eeu-035079	Erinaceus europaeus	91.84	0.00e+00	748.00
IUUC-Fca-035693	Felis catus	90.68	0.00e+00	743.00
IUUC-Fal-037345	Ficedula albicollis	90.65	0.00e+00	674.00
IUUC-Gmo-039222	Gadus morhua	91.98	0.00e+00	640.00
IUUC-Gga-040320	Gallus gallus	90.65	0.00e+00	675.00
IUUC-Gac-042644	Gasterosteus aculeatus	86.12	0.00e+00	649.00
IUUC-Ggo-044489	Gorilla gorilla	90.91	0.00e+00	747.00
IUUC-Hsa-046434	Homo sapiens	92.66	0.00e+00	766.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	93.67	2.00e-176	610.00
IUUC-Loc-052790	Lepisosteus oculatus	83.93	0.00e+00	692.00
IUUC-Laf-054255	Loxodonta africana	91.86	0.00e+00	753.00
IUUC-Mcc-055610	Macaca mulatta	92.37	0.00e+00	759.00
IUUC-Meu-056819	Macropus eugenii	86.48	0.00e+00	693.00
IUUC-Mga-059740	Meleagris gallopavo	85.40	0.00e+00	710.00
IUUC-Mmr-061221	Microcebus murinus	92.41	0.00e+00	764.00
IUUC-Mdo-062619	Monodelphis domestica	91.22	0.00e+00	677.00
IUUC-Mmu-064266	Mus musculus	92.41	0.00e+00	766.00
IUUC-Mpu-065766	Mustela putorius furo	99.34	0.00e+00	627.00
IUUC-Mlu-067221	Myotis lucifugus	90.18	0.00e+00	738.00
IUUC-Nle-069515	Nomascus leucogenys	99.68	0.00e+00	660.00
IUUC-Opr-070195	Ochotona princeps	83.97	0.00e+00	674.00
IUUC-Ont-071535	Oreochromis niloticus	73.42	2.00e-168	584.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.84	2.00e-107	380.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.67	0.00e+00	629.00
IUUC-Ola-086578	Oryzias latipes	94.01	0.00e+00	638.00
IUUC-Oga-089090	Otolemur garnettii	91.94	0.00e+00	759.00
IUUC-Oar-090017	Ovis aries	89.09	0.00e+00	725.00
IUUC-Ptr-091280	Pan troglodytes	90.13	0.00e+00	727.00
IUUC-Pan-092198	Papio anubis	99.37	0.00e+00	661.00
IUUC-Psi-093030	Pelodiscus sinensis	85.11	0.00e+00	712.00
IUUC-Pma-094140	Petromyzon marinus	72.30	3.00e-90	323.00
IUUC-Pfo-097182	Poecilia formosa	92.59	0.00e+00	644.00
IUUC-Pab-098157	Pongo abelii	92.07	0.00e+00	680.00
IUUC-Pca-100988	Procavia capensis	71.90	2.00e-157	548.00
IUUC-Pva-102232	Pteropus vampyrus	79.43	1.00e-161	561.00
IUUC-Rno-105526	Rattus norvegicus	88.45	0.00e+00	643.00
IUUC-Sha-106754	Sarcophilus harrisii	90.38	0.00e+00	734.00
IUUC-Ssc-115390	Sus scrofa	92.42	0.00e+00	763.00
IUUC-Tgu-117377	Taeniopygia guttata	87.28	0.00e+00	707.00
IUUC-Tru-117938	Takifugu rubripes	93.71	0.00e+00	639.00
IUUC-Tsy-119392	Tarsius syrichta	81.52	0.00e+00	635.00
IUUC-Tni-119834	Tetraodon nigroviridis	67.34	1.00e-159	555.00
IUUC-Tbe-127469	Tupaia belangeri	89.63	0.00e+00	685.00
IUUC-Ttr-128252	Tursiops truncatus	88.89	0.00e+00	722.00
IUUC-Vpa-130173	Vicugna pacos	80.95	5.00e-158	550.00
IUUC-Xtr-131803	Xenopus tropicalis	85.06	0.00e+00	702.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence