iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000017920.6	ENSPTRT00000045204.2	ENSPTRP00000044121.2
ENSPTRG00000017920.6	ENSPTRT00000062062.2	ENSPTRP00000054613.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.40e-07	31.2	16	61

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw.pglknssskefrCPlCr 46
           C +C  +++d  +++pCgH+f++ Cl ++ +   +ss k  +CPlC+
   Q: 16   CTLCAGPLED-AVTVPCGHTFCRLCLPALsQMGAQSSGKILLCPLCQ 61
           9*********.999************6663334445666668****7 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MPATPSLKVV HELPACTLCA GPLEDAVTVP CGHTFCRLCL PALSQMGAQS SGKILLCPLC 60
QEEEQAETPM APVPLGPLGE TYCEEHGEKI YFFCENDAEF LCVFCREGPT HQAHTVGFLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTTGATGC TGTGGGCACG CCTCAGAGCC AGAAGTTTAT GGCTCCCACC TGCTCAATCT 60
GACAGGAAGC TTCTGCTCCC CAGTTCTCCC CAGCCACTGT GGTCTACAGA TTCCAGGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1901253--P:negative regulation of intracellular transport of viral material
GO:1902187--P:negative regulation of viral release from host cell
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1900246--P:positive regulation of RIG-I signaling pathway
GO:0032481--P:positive regulation of type I interferon production

KEGG

ptr:471954

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012749	Bos taurus	88.06	5.00e-177	613.00
IUUC-Cja-019423	Callithrix jacchus	90.97	0.00e+00	823.00
IUUC-Csa-023062	Chlorocebus sabaeus	98.87	5.00e-136	476.00
IUUC-Dor-030723	Dipodomys ordii	72.26	0.00e+00	672.00
IUUC-Eca-033832	Equus caballus	80.95	5.00e-129	453.00
IUUC-Eeu-035346	Erinaceus europaeus	80.56	5.00e-123	433.00
IUUC-Ggo-044848	Gorilla gorilla	99.57	0.00e+00	877.00
IUUC-Hsa-046266	Homo sapiens	98.92	0.00e+00	854.00
IUUC-Itr-048326	Ictidomys tridecemlineatus	78.66	0.00e+00	703.00
IUUC-Mcc-055554	Macaca mulatta	96.99	0.00e+00	833.00
IUUC-Mdo-062286	Monodelphis domestica	63.48	6.00e-166	577.00
IUUC-Mmu-063387	Mus musculus	73.99	1.00e-115	409.00
IUUC-Nle-069027	Nomascus leucogenys	98.49	0.00e+00	852.00
IUUC-Opr-070615	Ochotona princeps	76.77	0.00e+00	694.00
IUUC-Ocu-074940	Oryctolagus cuniculus	82.37	0.00e+00	707.00
IUUC-Pan-091860	Papio anubis	93.98	0.00e+00	827.00
IUUC-Pab-097674	Pongo abelii	97.42	0.00e+00	839.00
IUUC-Pva-102190	Pteropus vampyrus	81.08	0.00e+00	755.00
IUUC-Sar-113135	Sorex araneus	71.80	2.00e-124	438.00
IUUC-Ssc-115476	Sus scrofa	82.15	0.00e+00	671.00
IUUC-Tbe-127674	Tupaia belangeri	75.25	3.00e-114	404.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence