iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020512

Ensembl Protein ID

ENSCAFP00000023878.3

UniProt Accession

F1Q0K8; F1Q0K8_CANLF

Genbank Protein ID

ENSCAFP00000023878

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03018198

Gene Name

WDFY1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000016204.3	ENSCAFT00000025711.3	ENSCAFP00000023878.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-13	48.8	207	238

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH d+v +l++   ++ lvs+s Dg i vW++
   Q: 207  GHHDRVQALCYlqLTRQLVSCSSDGGIAVWNM 238
           79999****99884489*************97 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MRPGPKGTSD SHRTIRVWLK RDSGQYWPSI YHTMASPCSA MAYHHDSRRV FVGQDNGAVM 60
EFHVSEDFNK MNFIKTYPAH QNRVSAIIFS LAAEWVISTG HDKCVSWMCT RSGNMLGRHF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATAGCCCC CTCTGCAGCA TAGCTGTACT GGAATCCTGC AGTTCGCAAG GCAGAATGAT 60
ACAATATGTG GAAGGGGAGT GTGGGTTGGA GAGGGGAGGT CTCCGACGTC AGTGATTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00064--FYVE
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005634--C:nucleus
GO:0005545--F:1-phosphatidylinositol binding
GO:0046872--F:metal ion binding
GO:0034141--P:positive regulation of toll-like receptor 3 signaling pathway
GO:0034145--P:positive regulation of toll-like receptor 4 signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001526	Ailuropoda melanoleuca	96.72	0.00e+00	747.00
IUUC-Apl-003661	Anas platyrhynchos	91.41	0.00e+00	716.00
IUUC-Aca-005225	Anolis carolinensis	89.07	0.00e+00	693.00
IUUC-Ame-011044	Astyanax mexicanus	73.84	2.00e-164	572.00
IUUC-Bta-012602	Bos taurus	96.45	0.00e+00	748.00
IUUC-Cja-019529	Callithrix jacchus	96.17	0.00e+00	747.00
IUUC-Cpo-022239	Cavia porcellus	93.17	0.00e+00	724.00
IUUC-Csa-023535	Chlorocebus sabaeus	96.76	0.00e+00	693.00
IUUC-Cho-024858	Choloepus hoffmanni	75.14	9.00e-159	553.00
IUUC-Dre-028520	Danio rerio	77.32	7.00e-173	599.00
IUUC-Dno-030005	Dasypus novemcinctus	96.72	0.00e+00	749.00
IUUC-Dor-030500	Dipodomys ordii	96.94	3.00e-173	600.00
IUUC-Ete-032870	Echinops telfairi	81.17	7.00e-147	513.00
IUUC-Eca-033284	Equus caballus	96.99	0.00e+00	749.00
IUUC-Fca-036212	Felis catus	97.78	0.00e+00	744.00
IUUC-Fal-037595	Ficedula albicollis	90.16	0.00e+00	719.00
IUUC-Gmo-038664	Gadus morhua	79.89	0.00e+00	649.00
IUUC-Gga-040400	Gallus gallus	90.16	0.00e+00	717.00
IUUC-Gac-041434	Gasterosteus aculeatus	80.87	0.00e+00	650.00
IUUC-Hsa-045884	Homo sapiens	96.72	0.00e+00	750.00
IUUC-Itr-048815	Ictidomys tridecemlineatus	98.09	0.00e+00	649.00
IUUC-Lch-049995	Latimeria chalumnae	86.34	0.00e+00	687.00
IUUC-Loc-052075	Lepisosteus oculatus	83.52	0.00e+00	666.00
IUUC-Laf-054345	Loxodonta africana	95.63	0.00e+00	746.00
IUUC-Mcc-055293	Macaca mulatta	95.63	0.00e+00	740.00
IUUC-Mga-059585	Meleagris gallopavo	90.61	0.00e+00	717.00
IUUC-Mmr-061268	Microcebus murinus	96.72	0.00e+00	751.00
IUUC-Mdo-061857	Monodelphis domestica	91.26	0.00e+00	723.00
IUUC-Mmu-063789	Mus musculus	95.90	0.00e+00	747.00
IUUC-Mpu-066391	Mustela putorius furo	96.72	0.00e+00	749.00
IUUC-Mlu-067636	Myotis lucifugus	95.57	0.00e+00	731.00
IUUC-Nle-068974	Nomascus leucogenys	96.45	0.00e+00	746.00
IUUC-Opr-070553	Ochotona princeps	80.87	2.00e-174	605.00
IUUC-Oan-073659	Ornithorhynchus anatinus	93.53	0.00e+00	681.00
IUUC-Ocu-074034	Oryctolagus cuniculus	96.17	0.00e+00	746.00
IUUC-Ola-087030	Oryzias latipes	80.05	0.00e+00	649.00
IUUC-Oga-087962	Otolemur garnettii	97.23	0.00e+00	744.00
IUUC-Oar-089377	Ovis aries	96.45	0.00e+00	748.00
IUUC-Ptr-090728	Pan troglodytes	96.17	0.00e+00	748.00
IUUC-Pan-092130	Papio anubis	95.36	0.00e+00	739.00
IUUC-Psi-093886	Pelodiscus sinensis	91.41	0.00e+00	718.00
IUUC-Pfo-097254	Poecilia formosa	82.29	0.00e+00	654.00
IUUC-Pab-097594	Pongo abelii	96.45	0.00e+00	749.00
IUUC-Pca-100741	Procavia capensis	87.22	0.00e+00	642.00
IUUC-Pva-102441	Pteropus vampyrus	95.65	0.00e+00	697.00
IUUC-Rno-105767	Rattus norvegicus	95.63	0.00e+00	745.00
IUUC-Sha-106731	Sarcophilus harrisii	92.52	0.00e+00	719.00
IUUC-Ssc-115316	Sus scrofa	97.10	5.00e-120	423.00
IUUC-Tgu-116691	Taeniopygia guttata	90.16	0.00e+00	717.00
IUUC-Tru-118169	Takifugu rubripes	81.15	0.00e+00	649.00
IUUC-Tsy-119047	Tarsius syrichta	84.02	2.00e-178	618.00
IUUC-Tni-120708	Tetraodon nigroviridis	81.47	0.00e+00	648.00
IUUC-Tbe-127442	Tupaia belangeri	97.50	0.00e+00	743.00
IUUC-Ttr-128779	Tursiops truncatus	82.79	0.00e+00	626.00
IUUC-Vpa-130488	Vicugna pacos	93.75	5.00e-119	419.00
IUUC-Xtr-131994	Xenopus tropicalis	81.15	0.00e+00	658.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence