iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060097

UUCD1 version

UUC-MeG-00075

Ensembl Protein ID

ENSMGAP00000000907.1

UniProt Accession

G1MRR2; G1MRR2_MELGA

Protein Name

Uncharacterized protein

Gene Name

FZR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000001395.2	ENSMGAT00000001555.1	ENSMGAP00000000907.1
ENSMGAG00000001395.2	ENSMGAT00000020650.1	ENSMGAP00000017541.1
ENSMGAG00000001395.2	ENSMGAT00000018658.1	ENSMGAP00000018846.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	1.90e-133	444.1	179	483
E3 adaptor/Cullin RING/DCX/DWD	7.70e-20	69.9	358	398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+gtl+avGt+kg v+i+D+++ kk
   Q: 179  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGTLVAVGTHKGFVQIWDAAAGKK 267
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           +++l+gh+arvgaL+Wna++lssGsrd++il+rd+r++ ++     + ++ + C  k +  a lL sGG   ++ vw++ss +P+++++
   Q: 268  LSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPCSRsGGSRVNNVHACRRKQSLGAMLLWSGGSSAELLVWNHSSLSPVQQYT 356
           **************************************999856677788899************************************ PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l++idtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+g
   Q: 357  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 445
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k++++
   Q: 446  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 483
           *********************************99875 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGs..dDgtikvWDlrtgvllk 37
           H + v ++a+  +  +ll+sG+   D  i+ W++ tg +l+
   Q: 358  HLAAVKAIAWspHQhGLLASGGgtADRCIRFWNTLTGQPLQ 398
           88899******633699***7777**********9998876 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MDQDYERRLL RQINIQNENT MPCVAEMRRT LTPSNSPMSS PSKHGDRFIP SRAGANWSIN 60
FHRINENEKS PSQNRKAKDA TSDNGKDGLA YSALLKNELL GAGIEKVQDP QTEDRRLQPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGACTAAT TACTGATTGG ACTTCATGAG CATAAAGCCC TGAGATTGCT GCACTCCCCA 60
GCCCTGATCC TTCCAGCATG GACCAGGATT ATGAGAGACG TCTCCTGCGC CAAATCAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0031572--P:G2 DNA damage checkpoint
GO:0070306--P:lens fiber cell differentiation
GO:0090344--P:negative regulation of cell aging
GO:0008284--P:positive regulation of cell proliferation
GO:0045732--P:positive regulation of protein catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	60.26	5.00e-103	367.00
IUUC-Aml-002003	Ailuropoda melanoleuca	87.80	0.00e+00	852.00
IUUC-Atr-002753	Amborella trichopoda	54.69	1.00e-121	429.00
IUUC-Apl-003212	Anas platyrhynchos	93.76	0.00e+00	923.00
IUUC-Aly-005442	Arabidopsis lyrata	54.30	6.00e-128	450.00
IUUC-Ath-006938	Arabidopsis thaliana	54.55	2.00e-126	445.00
IUUC-Acl-008269	Aspergillus clavatus	46.09	5.00e-118	417.00
IUUC-Afl-008432	Aspergillus flavus	46.90	3.00e-117	415.00
IUUC-Afu-008829	Aspergillus fumigatus	46.95	7.00e-119	420.00
IUUC-Ani-009471	Aspergillus nidulans	46.49	7.00e-117	414.00
IUUC-Ang-009711	Aspergillus niger	47.28	2.00e-116	412.00
IUUC-Aor-010118	Aspergillus oryzae	46.90	3.00e-117	415.00
IUUC-Ate-010534	Aspergillus terreus	47.12	4.00e-117	414.00
IUUC-Ame-011011	Astyanax mexicanus	85.63	0.00e+00	817.00
IUUC-Bgr-012013	Blumeria graminis	46.89	3.00e-116	412.00
IUUC-Bta-012586	Bos taurus	92.35	0.00e+00	915.00
IUUC-Bci-013807	Botrytis cinerea	47.76	3.00e-111	395.00
IUUC-Bdi-014981	Brachypodium distachyon	66.78	5.00e-118	417.00
IUUC-Bol-016301	Brassica oleracea	53.51	2.00e-125	442.00
IUUC-Bra-017453	Brassica rapa	53.51	1.00e-125	442.00
IUUC-Cel-018472	Caenorhabditis elegans	61.64	3.00e-132	465.00
IUUC-Cja-019929	Callithrix jacchus	91.40	0.00e+00	904.00
IUUC-Cfa-020977	Canis familiaris	91.60	0.00e+00	907.00
IUUC-Cpo-021537	Cavia porcellus	92.15	0.00e+00	914.00
IUUC-Csa-023389	Chlorocebus sabaeus	91.75	0.00e+00	909.00
IUUC-Cin-025327	Ciona intestinalis	65.09	2.00e-165	574.00
IUUC-Csv-025921	Ciona savignyi	62.83	8.00e-176	609.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	48.29	6.00e-119	421.00
IUUC-Cne-026933	Cryptococcus neoformans	54.66	1.00e-112	399.00
IUUC-Cme-027143	Cyanidioschyzon merolae	58.44	3.00e-105	376.00
IUUC-Dre-027470	Danio rerio	83.80	0.00e+00	813.00
IUUC-Dno-029629	Dasypus novemcinctus	82.49	0.00e+00	724.00
IUUC-Dor-030187	Dipodomys ordii	81.00	0.00e+00	794.00
IUUC-Dse-031502	Dothistroma septosporum	46.43	2.00e-110	392.00
IUUC-Dme-031858	Drosophila melanogaster	69.37	6.00e-178	616.00
IUUC-Ete-032562	Echinops telfairi	79.68	0.00e+00	759.00
IUUC-Eca-034210	Equus caballus	91.95	0.00e+00	913.00
IUUC-Fca-035839	Felis catus	86.92	0.00e+00	856.00
IUUC-Fal-036895	Ficedula albicollis	93.56	0.00e+00	921.00
IUUC-Fox-037814	Fusarium oxysporum	59.57	2.00e-110	391.00
IUUC-Fso-038420	Fusarium solani	46.77	3.00e-118	418.00
IUUC-Gmo-039544	Gadus morhua	83.03	0.00e+00	789.00
IUUC-Ggr-039774	Gaeumannomyces graminis	48.07	1.00e-117	416.00
IUUC-Gga-041025	Gallus gallus	93.96	0.00e+00	926.00
IUUC-Gac-041596	Gasterosteus aculeatus	83.60	0.00e+00	800.00
IUUC-Gma-042657	Glycine max	51.69	2.00e-124	439.00
IUUC-Ggo-045599	Gorilla gorilla	89.40	0.00e+00	865.00
IUUC-Hsa-046695	Homo sapiens	91.20	0.00e+00	903.00
IUUC-Hvu-047486	Hordeum vulgare	61.92	1.00e-95	342.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	90.95	0.00e+00	907.00
IUUC-Kpa-049239	Komagataella pastoris	54.39	1.00e-108	386.00
IUUC-Lch-049827	Latimeria chalumnae	89.54	0.00e+00	867.00
IUUC-Lpe-051568	Leersia perrieri	48.21	2.00e-100	358.00
IUUC-Loc-052856	Lepisosteus oculatus	87.78	0.00e+00	842.00
IUUC-Laf-054321	Loxodonta africana	62.28	2.00e-150	525.00
IUUC-Mcc-055601	Macaca mulatta	91.75	0.00e+00	909.00
IUUC-Meu-056276	Macropus eugenii	62.50	6.00e-151	526.00
IUUC-Mor-057113	Magnaporthe oryzae	47.66	7.00e-118	417.00
IUUC-Mpo-057599	Magnaporthe poae	48.07	1.00e-117	416.00
IUUC-Mtr-057689	Medicago truncatula	54.41	7.00e-126	443.00
IUUC-Mla-059048	Melampsora laricipopulina	47.19	3.00e-106	378.00
IUUC-Mvi-060465	Microbotryum violaceum	49.07	3.00e-118	418.00
IUUC-Mmr-061151	Microcebus murinus	85.40	0.00e+00	811.00
IUUC-Mdo-063062	Monodelphis domestica	93.76	0.00e+00	924.00
IUUC-Mmu-063731	Mus musculus	91.75	0.00e+00	909.00
IUUC-Mac-065208	Musa acuminata	54.20	6.00e-117	413.00
IUUC-Mpu-066173	Mustela putorius furo	91.95	0.00e+00	910.00
IUUC-Mlu-068030	Myotis lucifugus	91.80	0.00e+00	909.00
IUUC-Nfi-068536	Neosartorya fischeri	46.95	2.00e-119	422.00
IUUC-Ncr-068734	Neurospora crassa	48.89	3.00e-120	425.00
IUUC-Nle-070163	Nomascus leucogenys	91.75	0.00e+00	908.00
IUUC-Opr-070974	Ochotona princeps	82.88	2.00e-135	474.00
IUUC-Ont-072507	Oreochromis niloticus	81.76	0.00e+00	813.00
IUUC-Oan-073634	Ornithorhynchus anatinus	90.48	3.00e-155	540.00
IUUC-Oba-075417	Oryza barthii	59.31	6.00e-100	357.00
IUUC-Obr-076123	Oryza brachyantha	65.80	4.00e-115	408.00
IUUC-Ogl-077294	Oryza glaberrima	51.90	7.00e-116	410.00
IUUC-Ogu-077996	Oryza glumaepatula	51.68	1.00e-114	406.00
IUUC-Oin-080172	Oryza indica	66.45	3.00e-115	408.00
IUUC-Olo-081068	Oryza longistaminata	66.45	3.00e-115	407.00
IUUC-Ome-081250	Oryza meridionalis	52.36	3.00e-117	415.00
IUUC-Oni-083048	Oryza nivara	51.90	7.00e-116	410.00
IUUC-Opu-083333	Oryza punctata	52.33	3.00e-116	411.00
IUUC-Oru-085001	Oryza rufipogon	51.90	7.00e-116	410.00
IUUC-Osa-086243	Oryza sativa	51.90	7.00e-116	410.00
IUUC-Ola-087094	Oryzias latipes	82.41	0.00e+00	758.00
IUUC-Oga-088911	Otolemur garnettii	92.35	0.00e+00	915.00
IUUC-Oar-089508	Ovis aries	92.35	0.00e+00	915.00
IUUC-Ptr-090967	Pan troglodytes	79.55	1.00e-173	601.00
IUUC-Pan-092147	Papio anubis	91.20	0.00e+00	903.00
IUUC-Psi-093702	Pelodiscus sinensis	93.76	0.00e+00	923.00
IUUC-Pma-094581	Petromyzon marinus	79.25	0.00e+00	737.00
IUUC-Pno-095139	Phaeosphaeria nodorum	54.85	6.00e-99	354.00
IUUC-Ppa-095366	Physcomitrella patens	55.36	1.00e-128	452.00
IUUC-Pfo-096309	Poecilia formosa	84.00	0.00e+00	803.00
IUUC-Pab-098762	Pongo abelii	78.52	2.00e-175	607.00
IUUC-Pop-098924	Populus trichocarpa	53.74	2.00e-121	429.00
IUUC-Pca-100565	Procavia capensis	86.16	0.00e+00	798.00
IUUC-Ppe-101924	Prunus persica	54.75	4.00e-125	441.00
IUUC-Pva-102602	Pteropus vampyrus	89.18	0.00e+00	865.00
IUUC-Pgr-103466	Puccinia graminis	48.41	1.00e-106	380.00
IUUC-Ptt-103888	Puccinia triticina	50.85	3.00e-96	345.00
IUUC-Pte-104097	Pyrenophora teres	45.83	4.00e-114	404.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	42.05	1.00e-96	346.00
IUUC-Rno-105028	Rattus norvegicus	91.35	0.00e+00	904.00
IUUC-Sce-106240	Saccharomyces cerevisiae	37.24	1.00e-85	310.00
IUUC-Sha-107107	Sarcophilus harrisii	79.96	0.00e+00	764.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	46.10	8.00e-103	366.00
IUUC-Spo-108056	Schizosaccharomyces pombe	47.15	7.00e-105	373.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	48.57	9.00e-114	403.00
IUUC-Smo-108878	Selaginella moellendorffii	56.32	4.00e-133	468.00
IUUC-Sit-110550	Setaria italica	52.61	7.00e-117	413.00
IUUC-Sly-111446	Solanum lycopersicum	53.19	2.00e-122	432.00
IUUC-Stu-112491	Solanum tuberosum	52.97	1.00e-121	429.00
IUUC-Sar-112962	Sorex araneus	70.23	1.00e-98	352.00
IUUC-Sbi-114386	Sorghum bicolor	51.75	3.00e-115	407.00
IUUC-Sre-115222	Sporisorium reilianum	44.47	1.00e-116	413.00
IUUC-Ssc-116171	Sus scrofa	92.35	0.00e+00	914.00
IUUC-Tgu-116878	Taeniopygia guttata	87.33	0.00e+00	840.00
IUUC-Tru-118222	Takifugu rubripes	82.90	0.00e+00	793.00
IUUC-Tni-119863	Tetraodon nigroviridis	83.60	0.00e+00	795.00
IUUC-Tca-121599	Theobroma cacao	52.25	5.00e-123	434.00
IUUC-Tre-122249	Trichoderma reesei	48.28	2.00e-120	425.00
IUUC-Tvi-122675	Trichoderma virens	46.24	5.00e-120	424.00
IUUC-Tae-123028	Triticum aestivum	55.95	9.00e-116	410.00
IUUC-Tur-126545	Triticum urartu	59.82	6.00e-104	370.00
IUUC-Tme-127151	Tuber melanosporum	51.43	2.00e-131	461.00
IUUC-Tbe-128056	Tupaia belangeri	79.94	4.00e-146	509.00
IUUC-Ttr-129055	Tursiops truncatus	90.80	0.00e+00	892.00
IUUC-Uma-129555	Ustilago maydis	44.28	4.00e-116	411.00
IUUC-Vda-130027	Verticillium dahliae	45.64	7.00e-120	424.00
IUUC-Vvi-131749	Vitis vinifera	52.57	1.00e-122	432.00
IUUC-Xtr-132808	Xenopus tropicalis	86.72	0.00e+00	850.00
IUUC-Xma-133183	Xiphophorus maculatus	84.00	0.00e+00	803.00
IUUC-Yli-134584	Yarrowia lipolytica	56.96	1.00e-116	412.00
IUUC-Zma-135640	Zea mays	64.47	3.00e-114	405.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence