iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048870

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01017111

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000014301.2	ENSSTOT00000014309.2	ENSSTOP00000012815.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-24	85.0	326	357
UBD/Beta-Prp	2.50e-45	154.9	239	447

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 326  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 357
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 239  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 327
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 328  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 414
           ******99999.********************988874555555.55555555558*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 415  RRMVCCSAWSEDHpiCNLFTCGFDRQAIGWNIN 447
           ************9777899***********986 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MLEGQDSKLP SSVRTTLLEL FGQIEREFEN LYIENLELRR EIDTLNERLA AEGQAIDGAE 60
LSKGQLKTKA SHSTSQLSQK LKTTYKASTS KIVSSFKTTT SRAVCQLVKE YIGHRDGIWD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTGCCACC CGGGCTGGCT CCGGGCGGTG GAGAGCACAG CTGCTGTGAC AGGTAAGTGC 60
CGCCATCTTC CCAGCTGTCG AGCTCCTTGT CCTTCCCGTG GTACCTGGAG GAGGAGTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	96.04	0.00e+00	885.00
IUUC-Apl-003647	Anas platyrhynchos	95.16	0.00e+00	871.00
IUUC-Aca-004759	Anolis carolinensis	93.63	0.00e+00	876.00
IUUC-Ame-011103	Astyanax mexicanus	54.96	3.00e-126	444.00
IUUC-Bta-012718	Bos taurus	95.60	0.00e+00	880.00
IUUC-Cel-018499	Caenorhabditis elegans	42.52	5.00e-96	344.00
IUUC-Cja-019492	Callithrix jacchus	97.36	0.00e+00	921.00
IUUC-Cfa-020199	Canis familiaris	96.26	0.00e+00	920.00
IUUC-Cpo-022500	Cavia porcellus	92.09	0.00e+00	873.00
IUUC-Csa-023567	Chlorocebus sabaeus	98.24	0.00e+00	928.00
IUUC-Cho-025071	Choloepus hoffmanni	71.94	2.00e-165	575.00
IUUC-Cin-025460	Ciona intestinalis	45.09	1.00e-104	372.00
IUUC-Csv-026042	Ciona savignyi	46.65	6.00e-109	387.00
IUUC-Dre-028214	Danio rerio	83.30	0.00e+00	800.00
IUUC-Dno-029826	Dasypus novemcinctus	96.87	0.00e+00	832.00
IUUC-Dor-030967	Dipodomys ordii	98.06	0.00e+00	824.00
IUUC-Dme-031936	Drosophila melanogaster	49.58	1.00e-118	419.00
IUUC-Ete-032452	Echinops telfairi	93.19	0.00e+00	877.00
IUUC-Eca-033278	Equus caballus	96.48	0.00e+00	919.00
IUUC-Eeu-034592	Erinaceus europaeus	82.86	0.00e+00	754.00
IUUC-Fca-036431	Felis catus	96.71	0.00e+00	920.00
IUUC-Fal-037149	Ficedula albicollis	93.85	0.00e+00	865.00
IUUC-Gmo-038476	Gadus morhua	80.53	0.00e+00	734.00
IUUC-Gga-041099	Gallus gallus	94.95	0.00e+00	872.00
IUUC-Gac-042374	Gasterosteus aculeatus	85.40	0.00e+00	786.00
IUUC-Ggo-044683	Gorilla gorilla	89.23	0.00e+00	833.00
IUUC-Hsa-046658	Homo sapiens	97.58	0.00e+00	924.00
IUUC-Lch-050571	Latimeria chalumnae	85.60	0.00e+00	845.00
IUUC-Loc-052652	Lepisosteus oculatus	82.82	0.00e+00	825.00
IUUC-Laf-053712	Loxodonta africana	95.85	0.00e+00	907.00
IUUC-Mcc-055521	Macaca mulatta	98.24	0.00e+00	928.00
IUUC-Meu-056324	Macropus eugenii	89.89	0.00e+00	815.00
IUUC-Mga-060114	Meleagris gallopavo	95.16	0.00e+00	879.00
IUUC-Mmr-061176	Microcebus murinus	97.36	0.00e+00	919.00
IUUC-Mdo-061888	Monodelphis domestica	95.16	0.00e+00	852.00
IUUC-Mmu-063977	Mus musculus	98.24	0.00e+00	932.00
IUUC-Mpu-066220	Mustela putorius furo	81.38	7.00e-159	552.00
IUUC-Mlu-068155	Myotis lucifugus	96.70	0.00e+00	922.00
IUUC-Nle-069964	Nomascus leucogenys	97.80	0.00e+00	925.00
IUUC-Opr-070925	Ochotona princeps	97.10	5.00e-153	533.00
IUUC-Ont-071317	Oreochromis niloticus	87.03	0.00e+00	808.00
IUUC-Oan-072952	Ornithorhynchus anatinus	95.38	0.00e+00	880.00
IUUC-Ocu-073913	Oryctolagus cuniculus	99.12	0.00e+00	937.00
IUUC-Ola-087024	Oryzias latipes	85.75	0.00e+00	822.00
IUUC-Oga-087945	Otolemur garnettii	97.36	0.00e+00	930.00
IUUC-Oar-089854	Ovis aries	95.60	0.00e+00	870.00
IUUC-Ptr-091486	Pan troglodytes	97.80	0.00e+00	925.00
IUUC-Pan-091738	Papio anubis	98.24	0.00e+00	928.00
IUUC-Psi-093953	Pelodiscus sinensis	94.07	0.00e+00	867.00
IUUC-Pma-094560	Petromyzon marinus	76.91	0.00e+00	740.00
IUUC-Pfo-097222	Poecilia formosa	84.40	0.00e+00	798.00
IUUC-Pab-098778	Pongo abelii	92.31	0.00e+00	860.00
IUUC-Pca-100852	Procavia capensis	92.53	0.00e+00	858.00
IUUC-Pva-103130	Pteropus vampyrus	96.52	1.00e-112	400.00
IUUC-Rno-105848	Rattus norvegicus	87.91	0.00e+00	812.00
IUUC-Sha-106750	Sarcophilus harrisii	95.38	0.00e+00	884.00
IUUC-Sar-113749	Sorex araneus	87.69	0.00e+00	814.00
IUUC-Ssc-115691	Sus scrofa	93.85	0.00e+00	858.00
IUUC-Tgu-117365	Taeniopygia guttata	93.19	0.00e+00	821.00
IUUC-Tru-117595	Takifugu rubripes	85.05	0.00e+00	801.00
IUUC-Tsy-118973	Tarsius syrichta	76.65	3.00e-154	538.00
IUUC-Tni-120545	Tetraodon nigroviridis	84.68	0.00e+00	809.00
IUUC-Tbe-127976	Tupaia belangeri	70.99	0.00e+00	629.00
IUUC-Ttr-128472	Tursiops truncatus	93.19	0.00e+00	872.00
IUUC-Xtr-132621	Xenopus tropicalis	92.75	0.00e+00	843.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence