iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003353

Ensembl Protein ID

ENSAPLP00000014268.1

UniProt Accession

U3J441; U3J441_ANAPL

Genbank Protein ID

ENSAPLP00000014268

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01009455

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000014318.1	ENSAPLT00000015043.1	ENSAPLP00000014268.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-30	101.6	1341	1375
UBD/Beta-Prp	2.60e-42	144.8	1445	1652

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gH+  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1341 GHAKAVLCVDATDDLLFTGSKDRTCKVWNLVTGQE 1375
           7999999*99878*****************99976 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
             e++++++ ++p+g +++ ++  + ++ wdl+ ++ + +l+gh+  v++l++ +  +g d +v+Gs+d +i+++d+ +g   +   
   Q: 1445 AGENQINQIALNPTG-TFLYAAAGNSVRMWDLKRFQSTGKLTGHQGPVMCLTVERisNGqDLIVTGSKDHYIKMFDVTEGALGSVsp 1530
           567899********9.9999*********************************9998888******************998776577 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlqtgec 214
              ++ +h + +  +++++  + l+sGs D+ ++ Wdl++++ll++   +h+d v  ls+ + g + l+sg + g +klw++ t   
   Q: 1531 thnFEPPHYDGIEALAIMG--DNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWVCALSLLPAGaPVLLSGCRGGILKLWNVDTFAQ 1615
           7889999999********9..6799**********************999*********9999889999****************** PP
   S: 215  vrtlnghtdnvksvrfspnderlvsgssDgsiriW...d 250
           + +++gh+++++ + +   + ++ ++++D+++riW   +
   Q: 1616 IGEMKGHDSPINAICTN--SSHIFTAADDRTVRIWkarN 1652
           ************77777..****************4443 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

TSDGSFCLFL NRIRPQLAKE KIEGCHICTS VTPGEPQVFL GKDKAFTFDY VFNIDSQQEE 60
IYIQCIEKLI EGCFEGYNAT VFAYGQTGAG KTYTMGTGFD VNITEEEQGI ISRAVKHLFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTCTGATG GTTCTTTTTG TCTCTTCTTA AACAGAATTA GACCACAGCT AGCCAAAGAG 60
AAGATTGAAG GATGCCATAT TTGTACGTCT GTCACACCTG GGGAACCTCA AGTGTTCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	84.64	0.00e+00	2672.00
IUUC-Aca-004467	Anolis carolinensis	83.76	0.00e+00	2707.00
IUUC-Ame-011430	Astyanax mexicanus	63.78	0.00e+00	1223.00
IUUC-Bta-013485	Bos taurus	83.65	0.00e+00	2624.00
IUUC-Cel-018402	Caenorhabditis elegans	52.27	1.00e-147	517.00
IUUC-Cja-019385	Callithrix jacchus	83.11	0.00e+00	2601.00
IUUC-Cfa-020986	Canis familiaris	83.46	0.00e+00	2643.00
IUUC-Cpo-022297	Cavia porcellus	83.17	0.00e+00	2555.00
IUUC-Csa-023685	Chlorocebus sabaeus	83.52	0.00e+00	2631.00
IUUC-Cho-024531	Choloepus hoffmanni	78.55	0.00e+00	926.00
IUUC-Cin-025160	Ciona intestinalis	46.15	5.00e-88	318.00
IUUC-Csv-026158	Ciona savignyi	57.63	3.00e-175	609.00
IUUC-Dre-027839	Danio rerio	53.24	0.00e+00	991.00
IUUC-Dno-029972	Dasypus novemcinctus	81.69	0.00e+00	2523.00
IUUC-Ete-032872	Echinops telfairi	70.59	0.00e+00	920.00
IUUC-Eca-033518	Equus caballus	83.87	0.00e+00	2652.00
IUUC-Fca-036197	Felis catus	83.62	0.00e+00	2644.00
IUUC-Fal-037534	Ficedula albicollis	91.27	0.00e+00	2812.00
IUUC-Gmo-039407	Gadus morhua	64.27	0.00e+00	1296.00
IUUC-Gga-040687	Gallus gallus	91.99	0.00e+00	2817.00
IUUC-Gac-041626	Gasterosteus aculeatus	66.87	0.00e+00	2098.00
IUUC-Ggo-044457	Gorilla gorilla	83.95	0.00e+00	2639.00
IUUC-Hsa-046372	Homo sapiens	84.17	0.00e+00	2640.00
IUUC-Loc-052689	Lepisosteus oculatus	73.71	0.00e+00	2314.00
IUUC-Laf-054018	Loxodonta africana	81.97	0.00e+00	2502.00
IUUC-Mcc-055558	Macaca mulatta	84.29	0.00e+00	2647.00
IUUC-Meu-056080	Macropus eugenii	84.82	0.00e+00	920.00
IUUC-Mga-059283	Meleagris gallopavo	91.06	0.00e+00	2764.00
IUUC-Mmr-060773	Microcebus murinus	83.34	0.00e+00	2558.00
IUUC-Mdo-062688	Monodelphis domestica	83.03	0.00e+00	2378.00
IUUC-Mmu-063997	Mus musculus	83.59	0.00e+00	2551.00
IUUC-Mpu-066354	Mustela putorius furo	83.50	0.00e+00	2621.00
IUUC-Mlu-067599	Myotis lucifugus	82.65	0.00e+00	2617.00
IUUC-Nle-069477	Nomascus leucogenys	84.29	0.00e+00	2647.00
IUUC-Opr-070188	Ochotona princeps	81.35	0.00e+00	1261.00
IUUC-Ont-071938	Oreochromis niloticus	67.89	0.00e+00	2101.00
IUUC-Oan-073055	Ornithorhynchus anatinus	83.38	0.00e+00	2487.00
IUUC-Ocu-074302	Oryctolagus cuniculus	83.03	0.00e+00	2604.00
IUUC-Ola-086604	Oryzias latipes	65.15	0.00e+00	2024.00
IUUC-Oga-088799	Otolemur garnettii	82.96	0.00e+00	2352.00
IUUC-Oar-089629	Ovis aries	82.80	0.00e+00	2605.00
IUUC-Pan-092214	Papio anubis	83.50	0.00e+00	2622.00
IUUC-Psi-093757	Pelodiscus sinensis	82.54	0.00e+00	2527.00
IUUC-Pfo-096978	Poecilia formosa	63.25	0.00e+00	1240.00
IUUC-Pab-097984	Pongo abelii	84.29	0.00e+00	2632.00
IUUC-Pca-101061	Procavia capensis	70.91	0.00e+00	1565.00
IUUC-Pva-102306	Pteropus vampyrus	82.58	0.00e+00	2536.00
IUUC-Rno-105354	Rattus norvegicus	82.57	0.00e+00	2523.00
IUUC-Sha-106938	Sarcophilus harrisii	81.06	0.00e+00	2536.00
IUUC-Ssc-115810	Sus scrofa	83.72	0.00e+00	2589.00
IUUC-Tgu-117076	Taeniopygia guttata	88.82	0.00e+00	2676.00
IUUC-Tru-118091	Takifugu rubripes	61.21	0.00e+00	1172.00
IUUC-Tsy-119020	Tarsius syrichta	83.00	0.00e+00	2618.00
IUUC-Tni-120813	Tetraodon nigroviridis	61.69	0.00e+00	1169.00
IUUC-Tbe-127494	Tupaia belangeri	67.98	0.00e+00	836.00
IUUC-Ttr-128393	Tursiops truncatus	77.90	0.00e+00	2382.00
IUUC-Vpa-130675	Vicugna pacos	92.42	0.00e+00	686.00
IUUC-Xtr-132829	Xenopus tropicalis	77.43	0.00e+00	2446.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence