iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028532

Ensembl Protein ID

ENSDARP00000124286.2

UniProt Accession

F8W409; F8W409_DANRE

Genbank Protein ID

ENSDARP00000124286

Protein Name

Kinesin family member 21A

Genbank Nucleotide ID

BX957352

Gene Name

kif21a

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000061131.7	ENSDART00000149768.2	ENSDARP00000124286.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-25	89.3	1549	1577
UBD/Beta-Prp	9.90e-43	147.3	1375	1576

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWD 29
           gH++++++++ ++t+l +++dD t+k+W+
   Q: 1549 GHESPINSISTNSTHLFTAADDRTVKIWR 1577
           8********9855***************9 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee... 131
            e+++++++++p+g + + ++  + ++vwdl+ + c+ +l+gh   v++l++++  +g d +++Gs+d +i+++d+ +g   +    
   Q: 1375 GENQINQIYLNPSG-TVLYAAAGNSVRVWDLRRFVCTGKLTGHLGPVMCLTVDQtgNGqDLVITGSKDHYIKMFDVTEGAMGSIspt 1460
           56778888888887.788888888888888888888888888888888888888776678888888888888888888887766777 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
             ++ +h + + ++vv++  ++l+sGs D+ ++ Wdl +++ll++   +h d v  l + + +  l+sg + g +klw   t + + 
   Q: 1461 hnFEPPHYDGIESLVVQG--DCLFSGSRDNGIKKWDLTRKDLLQQVPNAHRDWVCALGVVPASAILLSGCRAGVLKLWHTDTLSPLG 1545
           777778888888888887..8888888888888888888888888877788888888888888888888888888888888888888 PP
   S: 217  tlnghtdnvksvrfspnderlvsgssDgsiriW 249
           + +gh+++++s+ +   +++l ++++D++++iW
   Q: 1546 EIRGHESPINSISTN--STHLFTAADDRTVKIW 1576
           888888888888888..8888888888888888 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MDDSTVRVAL RIRPQLAKEK IEGCHICTFV MPDEPQVVLG KDKAFTYDYV FDMDSTQDNI 60
YSNCTEKLIE GCFEGYNATI FAYGQTGSGK TYTMGTGFDV AIPDEDLGII PRAVTHLFKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGGGTCTG CGAGGAGGCG TGGTTTGGTG ACGCATTGCG GCTGGTCCTT CATGCTGGAG 60
TGTGCGTGGA TCAGATGAGC CCCGGACTCG AGGTGAACAT GCGAGAACAA GTGGCGAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	65.00	0.00e+00	1295.00
IUUC-Aca-004467	Anolis carolinensis	64.86	0.00e+00	1278.00
IUUC-Ame-011430	Astyanax mexicanus	84.75	0.00e+00	1592.00
IUUC-Bta-013485	Bos taurus	66.71	0.00e+00	2085.00
IUUC-Cel-018402	Caenorhabditis elegans	51.43	8.00e-150	525.00
IUUC-Cja-019385	Callithrix jacchus	64.21	0.00e+00	1257.00
IUUC-Cfa-020986	Canis familiaris	64.62	0.00e+00	1281.00
IUUC-Cpo-022297	Cavia porcellus	64.81	0.00e+00	1229.00
IUUC-Csa-023685	Chlorocebus sabaeus	64.97	0.00e+00	1284.00
IUUC-Cho-024531	Choloepus hoffmanni	75.98	7.00e-176	612.00
IUUC-Cin-025160	Ciona intestinalis	47.38	2.00e-86	313.00
IUUC-Dno-029972	Dasypus novemcinctus	75.93	0.00e+00	869.00
IUUC-Ete-032872	Echinops telfairi	63.19	2.00e-124	441.00
IUUC-Eca-033518	Equus caballus	67.08	0.00e+00	2122.00
IUUC-Fca-036197	Felis catus	64.20	0.00e+00	1278.00
IUUC-Fal-037534	Ficedula albicollis	64.35	0.00e+00	1244.00
IUUC-Gmo-039407	Gadus morhua	76.37	0.00e+00	813.00
IUUC-Gga-040687	Gallus gallus	69.37	0.00e+00	2084.00
IUUC-Gac-041626	Gasterosteus aculeatus	73.17	0.00e+00	2303.00
IUUC-Ggo-044457	Gorilla gorilla	64.68	0.00e+00	1277.00
IUUC-Hsa-046372	Homo sapiens	64.75	0.00e+00	1277.00
IUUC-Loc-052689	Lepisosteus oculatus	69.95	0.00e+00	2171.00
IUUC-Laf-054018	Loxodonta africana	64.70	0.00e+00	1966.00
IUUC-Mcc-055558	Macaca mulatta	65.03	0.00e+00	1283.00
IUUC-Meu-056080	Macropus eugenii	57.80	0.00e+00	1100.00
IUUC-Mmr-060773	Microcebus murinus	64.13	0.00e+00	1226.00
IUUC-Mdo-062688	Monodelphis domestica	63.53	0.00e+00	1253.00
IUUC-Mlu-067599	Myotis lucifugus	66.03	0.00e+00	2092.00
IUUC-Nle-069477	Nomascus leucogenys	64.84	0.00e+00	1278.00
IUUC-Ont-071938	Oreochromis niloticus	74.70	0.00e+00	2338.00
IUUC-Oan-073055	Ornithorhynchus anatinus	64.66	0.00e+00	1100.00
IUUC-Ola-086604	Oryzias latipes	73.19	0.00e+00	1395.00
IUUC-Oga-088799	Otolemur garnettii	65.15	0.00e+00	1290.00
IUUC-Oar-089629	Ovis aries	64.48	0.00e+00	1247.00
IUUC-Pan-092214	Papio anubis	64.97	0.00e+00	1284.00
IUUC-Psi-093757	Pelodiscus sinensis	66.87	0.00e+00	1212.00
IUUC-Pfo-096978	Poecilia formosa	76.79	0.00e+00	1494.00
IUUC-Pab-097984	Pongo abelii	64.55	0.00e+00	1274.00
IUUC-Pva-102306	Pteropus vampyrus	63.85	0.00e+00	1241.00
IUUC-Rno-105354	Rattus norvegicus	64.87	0.00e+00	1244.00
IUUC-Sha-106938	Sarcophilus harrisii	62.96	0.00e+00	1253.00
IUUC-Ssc-115810	Sus scrofa	63.50	0.00e+00	1240.00
IUUC-Tgu-117076	Taeniopygia guttata	63.46	0.00e+00	1200.00
IUUC-Tru-118091	Takifugu rubripes	72.66	0.00e+00	1407.00
IUUC-Tsy-119020	Tarsius syrichta	64.55	0.00e+00	1268.00
IUUC-Tni-120813	Tetraodon nigroviridis	71.76	0.00e+00	1385.00
IUUC-Tbe-127494	Tupaia belangeri	57.99	1.00e-151	531.00
IUUC-Ttr-128393	Tursiops truncatus	63.85	0.00e+00	1250.00
IUUC-Vpa-130675	Vicugna pacos	77.52	4.00e-169	589.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence