iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000002225.5	ENSGALT00000078114.1	ENSGALP00000054344.1
ENSGALG00000002225.5	ENSGALT00000003484.5	ENSGALP00000003479.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	67.49	1.00e-130	463.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gallus gallus

Protein Sequence
(Fasta)

MWASCCNWFC LDGSPEEMQA PQGARAQAYS NPGYSSFPSP TASEQSCKAC GLHFDSSSRK 60
HICLDCKKNF CTSCSSQPEG GPLLCHLCQR VRATAFQREE LIKMKVKDLR DYLALREIST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCTCGGGG AGGAGCCGCG GCCTGGGCCG GCACGGGGCC CTCCGCGGGA CGGGGCGCTG 60
AGGGACAGGT GAGGAGACGG CAGCGGGGCC CGGAGCGGGG TGAGAGGCTG CGGGGGACCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

gga:417529

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	66.12	3.00e-131	461.00
IUUC-Apl-004124	Anas platyrhynchos	82.87	5.00e-155	540.00
IUUC-Aly-005548	Arabidopsis lyrata	47.06	2.00e-08	54.70
IUUC-Ame-011616	Astyanax mexicanus	56.59	3.00e-99	354.00
IUUC-Bta-012374	Bos taurus	65.65	3.00e-133	467.00
IUUC-Cja-019780	Callithrix jacchus	66.21	6.00e-135	473.00
IUUC-Cfa-021252	Canis familiaris	68.32	2.00e-131	461.00
IUUC-Cpo-022047	Cavia porcellus	66.94	8.00e-136	476.00
IUUC-Csa-023161	Chlorocebus sabaeus	67.49	6.00e-140	489.00
IUUC-Cho-024316	Choloepus hoffmanni	65.12	9.00e-105	372.00
IUUC-Dre-028596	Danio rerio	53.33	5.00e-107	380.00
IUUC-Dno-029333	Dasypus novemcinctus	66.39	1.00e-135	476.00
IUUC-Ete-033163	Echinops telfairi	68.42	2.00e-129	455.00
IUUC-Eca-033994	Equus caballus	67.77	2.00e-138	485.00
IUUC-Eeu-035162	Erinaceus europaeus	61.07	4.00e-86	310.00
IUUC-Fca-036418	Felis catus	68.04	6.00e-141	493.00
IUUC-Fal-037427	Ficedula albicollis	82.27	5.00e-168	583.00
IUUC-Ggo-045436	Gorilla gorilla	67.49	5.00e-141	493.00
IUUC-Hsa-045798	Homo sapiens	67.49	5.00e-141	493.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	67.31	4.00e-133	467.00
IUUC-Lch-050639	Latimeria chalumnae	60.16	1.00e-116	412.00
IUUC-Laf-053355	Loxodonta africana	66.39	7.00e-130	456.00
IUUC-Mcc-055222	Macaca mulatta	65.84	5.00e-135	473.00
IUUC-Meu-056692	Macropus eugenii	65.01	3.00e-133	467.00
IUUC-Mga-059298	Meleagris gallopavo	97.50	0.00e+00	684.00
IUUC-Mmr-061792	Microcebus murinus	66.85	7.00e-133	466.00
IUUC-Mdo-062986	Monodelphis domestica	69.15	4.00e-142	497.00
IUUC-Mmu-063356	Mus musculus	68.32	2.00e-137	482.00
IUUC-Mpu-066273	Mustela putorius furo	67.77	5.00e-141	493.00
IUUC-Mlu-066953	Myotis lucifugus	67.77	5.00e-139	486.00
IUUC-Nle-070075	Nomascus leucogenys	67.77	1.00e-141	495.00
IUUC-Opr-070838	Ochotona princeps	66.12	4.00e-133	467.00
IUUC-Ont-071967	Oreochromis niloticus	47.65	3.00e-86	311.00
IUUC-Ocu-074807	Oryctolagus cuniculus	66.49	1.00e-137	482.00
IUUC-Obr-076159	Oryza brachyantha	41.07	5.00e-08	50.10
IUUC-Ola-086903	Oryzias latipes	67.63	2.00e-51	196.00
IUUC-Oga-088536	Otolemur garnettii	66.57	7.00e-131	459.00
IUUC-Oar-089838	Ovis aries	65.37	2.00e-131	461.00
IUUC-Ptr-090962	Pan troglodytes	67.49	5.00e-141	493.00
IUUC-Pan-092853	Papio anubis	66.94	6.00e-139	486.00
IUUC-Psi-093164	Pelodiscus sinensis	76.80	3.00e-148	517.00
IUUC-Pma-094104	Petromyzon marinus	44.13	6.00e-57	214.00
IUUC-Pab-098304	Pongo abelii	67.49	2.00e-140	491.00
IUUC-Pca-100316	Procavia capensis	65.56	1.00e-131	462.00
IUUC-Ppe-101490	Prunus persica	45.10	1.00e-08	54.30
IUUC-Pva-102612	Pteropus vampyrus	55.65	4.00e-103	367.00
IUUC-Rno-105449	Rattus norvegicus	67.49	5.00e-137	480.00
IUUC-Sha-107578	Sarcophilus harrisii	69.15	1.00e-130	459.00
IUUC-Sit-110649	Setaria italica	43.40	1.00e-08	52.00
IUUC-Sar-113638	Sorex araneus	66.67	9.00e-131	459.00
IUUC-Ssc-116401	Sus scrofa	68.32	1.00e-142	498.00
IUUC-Tru-118765	Takifugu rubripes	47.45	1.00e-79	289.00
IUUC-Tsy-118850	Tarsius syrichta	64.12	8.00e-104	369.00
IUUC-Tbe-128086	Tupaia belangeri	63.36	2.00e-129	454.00
IUUC-Vpa-130816	Vicugna pacos	73.26	3.00e-32	131.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence