iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092558

Ensembl Protein ID

ENSPANP00000012870.1

UniProt Accession

A0A096NIS2; A0A096NIS2_PAPAN

Genbank Protein ID

ENSPANP00000012870

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Genbank Nucleotide ID

AHZZ01040324

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000006022.1	ENSPANT00000026783.1	ENSPANP00000012870.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-07	31.8	186	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+ ++   +  +ll+s+s+Dgt+++W++r+g++l+
   Q: 186  GHTEFVSRISVvpTQpGLLLSSSGDGTLRLWEYRSGRQLH 225
           67777777776853369*******************9986 PP

Organism

Papio anubis

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MAGSVGLALC GQTLVVRGGS RFLATSTASS DDDSLFIYDC SAAEKKSQEN KGEDAPLDQG 60
SGVILASTFS KSGSYFALTD DSKRLILFRT KPWQCLSVRT VARRCTALTF IASEEKVLVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGCT CTGTGGGACT GGCGTTGTGC GGGCAGACGC TGGTGGTGCG GGGCGGCAGC 60
CGATTCCTGG CCACCTCCAC AGCAAGCAGG TGAGGGGGCC TTGGTCTTGG AACAGGGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	33.13	2.00e-10	60.50
IUUC-Apl-003975	Anas platyrhynchos	59.95	1.00e-120	426.00
IUUC-Aca-005170	Anolis carolinensis	54.69	2.00e-104	372.00
IUUC-Aly-005769	Arabidopsis lyrata	36.70	9.00e-24	104.00
IUUC-Ath-006733	Arabidopsis thaliana	35.38	1.00e-23	104.00
IUUC-Acl-008151	Aspergillus clavatus	34.46	8.00e-16	78.60
IUUC-Afl-008518	Aspergillus flavus	33.88	1.00e-17	84.00
IUUC-Afu-009102	Aspergillus fumigatus	38.56	3.00e-14	73.20
IUUC-Ani-009442	Aspergillus nidulans	30.30	9.00e-15	75.10
IUUC-Aor-010133	Aspergillus oryzae	28.12	5.00e-21	95.50
IUUC-Ate-010465	Aspergillus terreus	37.29	3.00e-14	73.20
IUUC-Ame-010613	Astyanax mexicanus	45.89	2.00e-87	315.00
IUUC-Bgr-012067	Blumeria graminis	45.88	2.00e-18	87.00
IUUC-Bta-012788	Bos taurus	79.52	0.00e+00	628.00
IUUC-Bdi-014458	Brachypodium distachyon	37.11	4.00e-19	89.00
IUUC-Bol-015373	Brassica oleracea	36.61	2.00e-23	104.00
IUUC-Bra-016644	Brassica rapa	38.33	1.00e-23	105.00
IUUC-Cpo-021963	Cavia porcellus	79.89	1.00e-173	602.00
IUUC-Csa-024148	Chlorocebus sabaeus	98.79	0.00e+00	702.00
IUUC-Cne-026834	Cryptococcus neoformans	35.10	4.00e-19	89.70
IUUC-Dre-028427	Danio rerio	46.95	2.00e-89	322.00
IUUC-Dno-028881	Dasypus novemcinctus	69.76	1.00e-157	549.00
IUUC-Dor-030522	Dipodomys ordii	74.69	3.00e-164	571.00
IUUC-Dme-032136	Drosophila melanogaster	32.83	4.00e-24	105.00
IUUC-Fca-035833	Felis catus	74.62	8.00e-166	576.00
IUUC-Fal-037497	Ficedula albicollis	58.03	5.00e-120	424.00
IUUC-Gga-040547	Gallus gallus	57.21	9.00e-125	439.00
IUUC-Gac-041761	Gasterosteus aculeatus	43.62	1.00e-82	299.00
IUUC-Gma-043941	Glycine max	36.71	5.00e-26	112.00
IUUC-Ggo-045340	Gorilla gorilla	96.38	0.00e+00	744.00
IUUC-Hsa-046403	Homo sapiens	96.14	0.00e+00	744.00
IUUC-Hvu-047643	Hordeum vulgare	39.33	6.00e-20	92.00
IUUC-Itr-048103	Ictidomys tridecemlineatus	80.48	2.00e-179	621.00
IUUC-Kpa-049283	Komagataella pastoris	34.59	2.00e-18	86.70
IUUC-Lch-050682	Latimeria chalumnae	49.39	4.00e-107	381.00
IUUC-Lpe-050712	Leersia perrieri	36.32	5.00e-23	102.00
IUUC-Loc-052599	Lepisosteus oculatus	51.83	2.00e-114	405.00
IUUC-Laf-054390	Loxodonta africana	77.11	1.00e-174	605.00
IUUC-Mcc-054747	Macaca mulatta	97.58	0.00e+00	732.00
IUUC-Mtr-058600	Medicago truncatula	39.23	9.00e-25	107.00
IUUC-Mla-059129	Melampsora laricipopulina	27.08	5.00e-13	68.20
IUUC-Mga-059876	Meleagris gallopavo	57.70	2.00e-123	435.00
IUUC-Mvi-060359	Microbotryum violaceum	29.35	8.00e-13	68.60
IUUC-Mmr-061518	Microcebus murinus	82.41	0.00e+00	650.00
IUUC-Mac-065625	Musa acuminata	32.29	5.00e-20	92.00
IUUC-Nfi-068402	Neosartorya fischeri	36.77	8.00e-15	75.10
IUUC-Nle-069914	Nomascus leucogenys	94.93	0.00e+00	705.00
IUUC-Ont-071555	Oreochromis niloticus	41.04	3.00e-76	278.00
IUUC-Oan-072951	Ornithorhynchus anatinus	67.77	3.00e-151	528.00
IUUC-Ocu-074679	Oryctolagus cuniculus	81.82	9.00e-171	592.00
IUUC-Oba-075355	Oryza barthii	27.47	3.00e-10	60.10
IUUC-Obr-076769	Oryza brachyantha	36.19	7.00e-24	104.00
IUUC-Ogl-077168	Oryza glaberrima	33.33	3.00e-24	105.00
IUUC-Ogu-078275	Oryza glumaepatula	26.51	1.00e-10	60.80
IUUC-Oin-079207	Oryza indica	33.33	3.00e-24	105.00
IUUC-Oni-082437	Oryza nivara	28.15	4.00e-11	62.80
IUUC-Opu-084031	Oryza punctata	33.46	2.00e-22	100.00
IUUC-Oru-084380	Oryza rufipogon	27.47	3.00e-10	60.10
IUUC-Osa-085327	Oryza sativa	33.33	3.00e-24	106.00
IUUC-Ola-086716	Oryzias latipes	43.57	2.00e-77	282.00
IUUC-Olu-087708	Ostreococcus lucimarinus	29.10	3.00e-13	69.30
IUUC-Oar-090239	Ovis aries	80.69	6.00e-172	596.00
IUUC-Ptr-090851	Pan troglodytes	96.38	0.00e+00	744.00
IUUC-Psi-093792	Pelodiscus sinensis	59.73	5.00e-129	454.00
IUUC-Ppa-095757	Physcomitrella patens	40.24	1.00e-20	94.40
IUUC-Pfo-096465	Poecilia formosa	41.13	1.00e-82	299.00
IUUC-Pab-097722	Pongo abelii	95.17	0.00e+00	727.00
IUUC-Pop-098979	Populus trichocarpa	35.87	3.00e-20	92.80
IUUC-Pca-100753	Procavia capensis	73.54	4.00e-114	404.00
IUUC-Ppe-101515	Prunus persica	34.50	4.00e-20	92.40
IUUC-Sja-107780	Schizosaccharomyces japonicus	25.99	5.00e-16	78.60
IUUC-Spo-108251	Schizosaccharomyces pombe	30.85	4.00e-13	68.90
IUUC-Smo-108938	Selaginella moellendorffii	37.31	3.00e-24	105.00
IUUC-Sit-110020	Setaria italica	35.57	2.00e-22	100.00
IUUC-Sly-111543	Solanum lycopersicum	34.62	1.00e-22	100.00
IUUC-Stu-111925	Solanum tuberosum	33.16	2.00e-22	100.00
IUUC-Sbi-114061	Sorghum bicolor	37.57	2.00e-22	100.00
IUUC-Tgu-117321	Taeniopygia guttata	59.25	1.00e-112	399.00
IUUC-Tru-118454	Takifugu rubripes	44.12	6.00e-80	290.00
IUUC-Tni-119894	Tetraodon nigroviridis	44.59	1.00e-76	280.00
IUUC-Tca-121746	Theobroma cacao	35.79	1.00e-21	97.80
IUUC-Tae-124114	Triticum aestivum	38.76	2.00e-19	89.70
IUUC-Tur-126254	Triticum urartu	32.95	3.00e-12	65.90
IUUC-Tbe-127683	Tupaia belangeri	52.72	3.00e-59	222.00
IUUC-Ttr-129056	Tursiops truncatus	75.66	5.00e-162	563.00
IUUC-Vvi-131428	Vitis vinifera	36.27	8.00e-22	98.20
IUUC-Xma-133605	Xiphophorus maculatus	41.69	6.00e-84	304.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence