iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118588

UUCD1 version

UUC-TaR-01063

Ensembl Protein ID

ENSTRUP00000004532.1

UniProt Accession

H2RWL2; H2RWL2_TAKRU

Protein Name

Uncharacterized protein

Gene Name

ube2d4; LOC101069170

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000001962.1	ENSTRUT00000004557.1	ENSTRUP00000004532.1
ENSTRUG00000001962.1	ENSTRUT00000004558.1	ENSTRUP00000004533.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.20e-54	184.2	5	134
UBD/UBC-like/UBD_UBC	1.90e-76	256.0	5	134

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l++dpp+++sa+pv + dl++w+++i+Gp+d+pY+ gvF l+i+fp+dYPfkPPkv f+tki+hPn+++nG++Cl+il+  
   Q: 5    RIQKELSDLQRDPPAQCSAGPVGD-DLFHWQATIMGPSDSPYQSGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR-- 90
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreey 133
           ++Wspal+v++vllsi+sll++pnp++pl  e+a+++k++re++
   Q: 91   SQWSPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADRERH 134
           *****************************************976 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel+dl+rd++aq+sa++v+ddlf+++ati+gp+dspy+ gvfflti++ptdypfkppkvaf+tkiyhpninsngsicldilrsqw
   Q: 5    RIQKELSDLQRDPPAQCSAGPVGDDLFHWQATIMGPSDSPYQSGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkeky 130
           s+alt+skvlls+csll+d++pddplv+eia+ yk+d+e++
   Q: 94   SPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADRERH 134
           **************************************986 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MALKRIQKEL SDLQRDPPAQ CSAGPVGDDL FHWQATIMGP SDSPYQSGVF FLTIHFPTDY 60
PFKPPKVAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTTGA AAAGAATTCA GAAGGTGAGG GGGTCTTGTT TTCTTTATTC TTTCTGGTGT 60
CTTTACGTTG TAGACTTGTT TCTTGTCGAG TGAATCTGAA AATCCGCGCA CGGCTGTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012632	Bos taurus	91.16	5.00e-78	282.00
IUUC-Gmo-038604	Gadus morhua	87.42	3.00e-74	270.00
IUUC-Gac-042577	Gasterosteus aculeatus	98.48	4.00e-75	273.00
IUUC-Itr-047868	Ictidomys tridecemlineatus	94.20	1.00e-74	271.00
IUUC-Oga-089011	Otolemur garnettii	92.48	3.00e-71	260.00
IUUC-Oar-090224	Ovis aries	87.07	2.00e-74	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence