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Tag Content
iUUCD ID IUUC-Dre-027698
Ensembl Protein ID ENSDARP00000024987.8
UniProt Accession F1QL15; F1QL15_DANRE
Genbank Protein ID ENSDARP00000024987
Protein Name Estrogen receptor; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
Genbank Nucleotide ID BX470265
Gene Name esr1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000004111.10 ENSDART00000166190.1 ENSDARP00000131705.1
ENSDARG00000004111.10 ENSDART00000024518.8 ENSDARP00000024987.8
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UMI 56.84 2.00e-133 473.00 IUUC-Hsa-046944
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Danio rerio
Functional Description
(View)

Functional Description


     The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
 The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
Protein Sequence
(Fasta)
MLPACVFPVM SGGQTSGEAV GARQRRRTSP SPEREALEEP SSPPAAHKLS PMYPKEEHSA 60
GGISSSVNYL DGAYEYPNPT QTFGTSSPAE PASVGYYPAP PDPHEEHLQT LGGGSSSPLM 120
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Protein Fasta Sequence


>IUUC-Dre-027698|UBD,UMI|Danio rerio
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Nucleotide Sequence
(Fasta)
AGTCAGAGAT ACATCAGTGA GAGACAGAAA GCATCCAGCC TGTAATGGGA CTCAAGTAAA 60
ACATCAGAGG AGTGAACATT TTGGTGAGGA TGCTGGAAAG AATTCAGCAA CCAATTTTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-027698|UBD,UMI|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0446--Lipid-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0754--Steroid-binding
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR024178--Oest_rcpt/oest-rel_rcp
IPR001292--Oestr_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA
PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2
Pfam

PF00104--Hormone_recep
PF02159--Oest_recep
PF00105--zf-C4
PRINTS

PR00398--STRDHORMONER
PR00047--STROIDFINGER
SMART

SM00430--HOLI
SM00399--ZnF_C4
Gene Ontology

GO:0005634--C:nucleus
GO:0030284--F:estrogen receptor activity
GO:0043565--F:sequence-specific DNA binding
GO:0005496--F:steroid binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0006351--P:transcription, DNA-templated
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001925 Ailuropoda melanoleuca 62.89 6.00e-126 444.00
IUUC-Apl-003688 Anas platyrhynchos 51.20 2.00e-125 442.00
IUUC-Aca-005222 Anolis carolinensis 52.38 4.00e-127 448.00
IUUC-Ame-010731 Astyanax mexicanus 70.67 0.00e+00 687.00
IUUC-Bta-013112 Bos taurus 62.53 2.00e-127 449.00
IUUC-Cja-019408 Callithrix jacchus 62.95 8.00e-128 451.00
IUUC-Cfa-020694 Canis familiaris 60.00 2.00e-127 449.00
IUUC-Cpo-021426 Cavia porcellus 60.88 4.00e-125 442.00
IUUC-Csa-023736 Chlorocebus sabaeus 62.95 6.00e-127 447.00
IUUC-Dno-029477 Dasypus novemcinctus 59.90 4.00e-125 442.00
IUUC-Dor-030572 Dipodomys ordii 61.08 2.00e-123 435.00
IUUC-Ete-032849 Echinops telfairi 49.58 3.00e-83 302.00
IUUC-Eca-033605 Equus caballus 62.27 2.00e-126 446.00
IUUC-Eeu-034683 Erinaceus europaeus 59.50 1.00e-55 211.00
IUUC-Fca-035928 Felis catus 61.76 2.00e-126 445.00
IUUC-Fal-036754 Ficedula albicollis 52.34 2.00e-132 466.00
IUUC-Gmo-038872 Gadus morhua 64.42 7.00e-132 463.00
IUUC-Gga-040988 Gallus gallus 51.98 2.00e-132 466.00
IUUC-Gac-042015 Gasterosteus aculeatus 75.58 5.00e-149 521.00
IUUC-Ggo-044749 Gorilla gorilla 62.95 4.00e-127 448.00
IUUC-Hsa-046944 Homo sapiens 62.95 9.00e-128 450.00
IUUC-Itr-048863 Ictidomys tridecemlineatus 61.10 6.00e-126 444.00
IUUC-Loc-052414 Lepisosteus oculatus 58.76 5.00e-172 597.00
IUUC-Mcc-054781 Macaca mulatta 62.95 4.00e-127 448.00
IUUC-Meu-056232 Macropus eugenii 61.65 3.00e-123 435.00
IUUC-Mga-059319 Meleagris gallopavo 51.98 1.00e-132 467.00
IUUC-Mmr-061636 Microcebus murinus 58.88 3.00e-56 212.00
IUUC-Mdo-062661 Monodelphis domestica 62.63 3.00e-126 445.00
IUUC-Mmu-063330 Mus musculus 63.76 9.00e-127 447.00
IUUC-Mpu-065757 Mustela putorius furo 61.24 2.00e-128 452.00
IUUC-Mlu-067712 Myotis lucifugus 60.75 6.00e-128 451.00
IUUC-Nle-069283 Nomascus leucogenys 62.95 3.00e-127 448.00
IUUC-Opr-070391 Ochotona princeps 61.24 1.00e-129 457.00
IUUC-Ont-071369 Oreochromis niloticus 59.28 4.00e-145 508.00
IUUC-Oan-073734 Ornithorhynchus anatinus 44.41 1.00e-54 206.00
IUUC-Ocu-074292 Oryctolagus cuniculus 62.44 4.00e-127 448.00
IUUC-Ola-087052 Oryzias latipes 62.57 2.00e-157 549.00
IUUC-Oga-088586 Otolemur garnettii 60.70 5.00e-124 438.00
IUUC-Oar-090156 Ovis aries 61.95 4.00e-129 454.00
IUUC-Ptr-091321 Pan troglodytes 62.95 4.00e-127 448.00
IUUC-Pan-092851 Papio anubis 62.95 3.00e-127 448.00
IUUC-Psi-093434 Pelodiscus sinensis 53.18 9.00e-137 480.00
IUUC-Pfo-097379 Poecilia formosa 62.04 9.00e-150 523.00
IUUC-Pab-097735 Pongo abelii 62.95 4.00e-127 448.00
IUUC-Pva-102125 Pteropus vampyrus 62.63 7.00e-127 447.00
IUUC-Rno-106121 Rattus norvegicus 63.76 8.00e-127 447.00
IUUC-Sha-107547 Sarcophilus harrisii 62.89 1.00e-126 446.00
IUUC-Sar-113650 Sorex araneus 50.15 6.00e-71 261.00
IUUC-Tgu-117175 Taeniopygia guttata 52.16 4.00e-132 464.00
IUUC-Tru-117545 Takifugu rubripes 60.92 7.00e-162 565.00
IUUC-Tsy-119586 Tarsius syrichta 53.88 2.00e-107 383.00
IUUC-Tni-120121 Tetraodon nigroviridis 59.22 2.00e-164 572.00
IUUC-Tbe-127548 Tupaia belangeri 51.24 2.00e-99 356.00
IUUC-Ttr-128374 Tursiops truncatus 58.91 3.00e-112 399.00
IUUC-Vpa-130464 Vicugna pacos 52.12 1.00e-80 293.00
IUUC-Xtr-132171 Xenopus tropicalis 54.70 1.00e-123 437.00
Created Date 25-Jun-2017

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