iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041899

UUCD1 version

UUC-GaA-00562

Ensembl Protein ID

ENSGACP00000014922.1

UniProt Accession

G3PBE8; G3PBE8_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000011278.1	ENSGACT00000014950.1	ENSGACP00000014922.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.90e-72	244.9	2076	2436

Active Site

Position(s)	Description	Evidence
2410	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtref.lallskelqnpdlglf......lysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           d ++ ++++f+gEe+++++G++r f +a  ++elq++ l+l+       + +++k+ l+p p s+     +++l +f+G+llg+a++
   Q: 2076 DPTYAFNIRFTGEEVHGTSGSFRQFpVAGCVRELQSSALSLLlcpsaaANRNKGKYILTPCPISY----AEEQLLHFFGQLLGIAIR 2158
           5667788******************778899***********55555444445899999999998....689*************** PP
   S: 84   dgrlldlplsksfyklllgkklsl.edleevdpelykslkeikena.esdieelgldltfsvseei...............lgetke 153
            + +l+l+l +sf+k l+g++l+  +dl+e d  +y+++k+ ++   e+++e+l++++++  ++ +                   +e
   Q: 2159 ADVPLPLDLLSSFWKGLVGESLDPdQDLQEADVLTYNYVKKFENTSdETELEALCAEISSLHHSGEspdspsrpcctftyvTMIGDE 2245
           **************************************8777766436677777777776655555788999999998866455567 PP
   S: 154  eeLkpgGenipVtneNkeeYvklvveyrlke.gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggy 239
           +eL++gG++ pV +eNk++Y ++v ++rl+e + ke+++a+r+G+ ++ipl+ll+++++ e+el +cG ++i++e lk++t+y+ g+
   Q: 2246 VELCQGGRSLPVSWENKDMYARAVRSLRLRElQNKECMTAVRAGLGSIIPLQLLTMLSPLEMELRTCGLPYINLEFLKAHTMYQVGL 2332
           77*****************************9******************************************************* PP
   S: 240  tedspaiqwFwevleefsseerkafLqFvTgssrlPl......gGfaelk....prlfvirk...dasddrlPssnTCfnyLkLPeY 313
           +e++++i++Fw +le+f++ee ++f++F+++++r+P+      gG ++ +    p+++  ++    + d+r+++++TC+++ kLP+Y
   Q: 2333 METDQHIEFFWIALEMFTQEELCKFIKFACNQERIPFtcpckdGGPDTAHvppyPMKIAPPDgaaGQPDSRYIRVETCMFMVKLPQY 2419
           *******************************************9999999998888888888*955666****************** PP
   S: 314  sskeilkekLlyAieet 330
           +s +++ ekL+yAi+++
   Q: 2420 TSLDVMLEKLRYAIHYR 2436
           **************986 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

PSRQNKMKEL ELLCSLKEVP LNFSDLENVV LALREKFFQE VNTMHLRSST SLAKTKALVK 60
SLMNRTELLL HVTIAPHCRS LTTTPAGTPG PASKSVSDAK SVIPMVKQPV FLRSMSAPSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCAGCAGGG AAAGTTGGAG AACAATACTC CTTTCTTTCA CGACTACCAC TTCTTTGAGG 60
TACCTTGTGC TACACACAAT TAGCAACTTC TCAGGAGACT ATTCCATTCC ACAGCAGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002256	Ailuropoda melanoleuca	85.01	0.00e+00	2830.00
IUUC-Apl-004161	Anas platyrhynchos	85.09	0.00e+00	2851.00
IUUC-Aca-005341	Anolis carolinensis	84.97	0.00e+00	2842.00
IUUC-Ame-011574	Astyanax mexicanus	90.61	0.00e+00	3035.00
IUUC-Bta-012514	Bos taurus	84.72	0.00e+00	1128.00
IUUC-Cja-019148	Callithrix jacchus	84.44	0.00e+00	2767.00
IUUC-Cfa-020499	Canis familiaris	84.84	0.00e+00	2828.00
IUUC-Cpo-021894	Cavia porcellus	85.30	0.00e+00	2433.00
IUUC-Csa-023079	Chlorocebus sabaeus	84.67	0.00e+00	2805.00
IUUC-Cho-024415	Choloepus hoffmanni	81.13	0.00e+00	2744.00
IUUC-Dre-027452	Danio rerio	88.67	0.00e+00	3048.00
IUUC-Dno-029595	Dasypus novemcinctus	84.71	0.00e+00	2822.00
IUUC-Dor-030849	Dipodomys ordii	81.52	0.00e+00	1139.00
IUUC-Ete-032563	Echinops telfairi	84.95	5.00e-149	521.00
IUUC-Eca-034202	Equus caballus	85.08	0.00e+00	2815.00
IUUC-Eeu-035175	Erinaceus europaeus	84.09	0.00e+00	949.00
IUUC-Fca-036295	Felis catus	85.01	0.00e+00	2830.00
IUUC-Fal-037003	Ficedula albicollis	85.54	0.00e+00	2876.00
IUUC-Gmo-038579	Gadus morhua	91.25	0.00e+00	4302.00
IUUC-Gga-040961	Gallus gallus	85.36	0.00e+00	2858.00
IUUC-Ggo-045099	Gorilla gorilla	84.61	0.00e+00	2801.00
IUUC-Hsa-046331	Homo sapiens	84.61	0.00e+00	2801.00
IUUC-Itr-048190	Ictidomys tridecemlineatus	84.42	0.00e+00	1125.00
IUUC-Lch-049923	Latimeria chalumnae	82.80	0.00e+00	1048.00
IUUC-Loc-052630	Lepisosteus oculatus	90.68	0.00e+00	2559.00
IUUC-Laf-053394	Loxodonta africana	84.78	0.00e+00	2833.00
IUUC-Mcc-055763	Macaca mulatta	84.61	0.00e+00	2800.00
IUUC-Meu-056039	Macropus eugenii	80.22	0.00e+00	2643.00
IUUC-Mga-059500	Meleagris gallopavo	85.19	0.00e+00	2858.00
IUUC-Mmr-060868	Microcebus murinus	78.45	0.00e+00	2579.00
IUUC-Mdo-062772	Monodelphis domestica	83.94	0.00e+00	2810.00
IUUC-Mmu-063606	Mus musculus	84.61	0.00e+00	2848.00
IUUC-Mpu-065860	Mustela putorius furo	82.37	0.00e+00	2737.00
IUUC-Mlu-067376	Myotis lucifugus	85.03	0.00e+00	2830.00
IUUC-Nle-069693	Nomascus leucogenys	81.79	0.00e+00	2682.00
IUUC-Ont-072470	Oreochromis niloticus	94.76	0.00e+00	3194.00
IUUC-Oan-073693	Ornithorhynchus anatinus	85.30	0.00e+00	2846.00
IUUC-Ocu-074032	Oryctolagus cuniculus	84.41	0.00e+00	2797.00
IUUC-Ola-087433	Oryzias latipes	93.97	0.00e+00	1603.00
IUUC-Oga-088546	Otolemur garnettii	84.95	0.00e+00	2828.00
IUUC-Oar-089643	Ovis aries	81.33	0.00e+00	675.00
IUUC-Ptr-090504	Pan troglodytes	84.61	0.00e+00	2805.00
IUUC-Pan-092543	Papio anubis	84.46	0.00e+00	2794.00
IUUC-Psi-093952	Pelodiscus sinensis	82.90	0.00e+00	2716.00
IUUC-Pfo-096356	Poecilia formosa	94.76	0.00e+00	3168.00
IUUC-Pab-098240	Pongo abelii	84.38	0.00e+00	2784.00
IUUC-Pca-100994	Procavia capensis	84.62	0.00e+00	1449.00
IUUC-Pva-102263	Pteropus vampyrus	83.50	0.00e+00	2761.00
IUUC-Rno-104888	Rattus norvegicus	84.73	0.00e+00	2834.00
IUUC-Sha-106944	Sarcophilus harrisii	83.93	0.00e+00	2826.00
IUUC-Sar-113556	Sorex araneus	77.76	0.00e+00	875.00
IUUC-Ssc-116187	Sus scrofa	86.08	0.00e+00	2725.00
IUUC-Tgu-116655	Taeniopygia guttata	85.04	0.00e+00	2861.00
IUUC-Tru-118093	Takifugu rubripes	93.83	0.00e+00	3133.00
IUUC-Tni-119739	Tetraodon nigroviridis	93.19	0.00e+00	1615.00
IUUC-Tbe-127962	Tupaia belangeri	75.91	3.00e-179	622.00
IUUC-Ttr-128819	Tursiops truncatus	84.29	0.00e+00	1691.00
IUUC-Vpa-130482	Vicugna pacos	83.16	0.00e+00	2296.00
IUUC-Xtr-132222	Xenopus tropicalis	83.83	0.00e+00	2852.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence