iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059684

UUCD1 version

UUC-MeG-00873

Ensembl Protein ID

ENSMGAP00000011194.2

UniProt Accession

G1NE64; G1NE64_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP53

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000010759.2	ENSMGAT00000012064.2	ENSMGAP00000011194.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.10e-17	62.1	31	348

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee...fs 85
           Gl N   +N+C++NS++Q+ +++  + +ll     + l          ++ + ++ +f+++++s++ka    ++ +al++  +    f+
   Q: 31   GLLNEpgQNSCFLNSAVQVSWMFDCFLQLLEL---QILIC----FLACCMFCGVKAIFSQFQHSREKALPSDNMRHALAESFKDeqrFQ 112
           55555447***************999999888...33332....2568**************999999999998888876544322399 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
                Da E+++ +l++++ +l                     +++ +  ++++++ ++ F ++l +q++c +c+ +s    pf+++  
   Q: 113  LGFMDDAAECFENILERIHFHLV-------------------PNSNTDMCTSKSCISHQKFAMTLYEQCVCRSCGASSDPL-PFTEFVR 181
           9999******************1...................12345678999**********************999554.7888888 PP
   S: 175  pvpgkeetkke........slq.dcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkve 254
            ++    +++          l+ +++++  ++ +  ++ +   ++c +k + ++   l ++Pe+ ++ L +   se+ +  e + +++ 
   Q: 182  YISTTALCNEVermmerheRLKpEMFAELLQAANTADDYRKCPSNCGQKIKIRRV--LMNCPEIVTIGLVWD--SEHSDLTEEVMRNLA 266
           8875555544455555666555378899999999998888888899988865554..6688***********..666667777777777 PP
   S: 255  fpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvlfYk 336
           + l L    + +++e++  ++ +  L+++++++      HY+a++ ++k + W+lfdD +V+e+  k+++v++ +     ++ +lfY 
   Q: 267  TQLYLPGLFYRVTDENA--KNSELFLVGMICYTS----RHYCAFAFHTKSCkWVLFDDANVKEIgtKWKDVVSRCIrchFQPLLLFYA 348
           66444444444444433..378888*******87....9********77767***********9767899999665888899999996 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MAWVKFLRKP GGNLGKVYQP GSILSLAPTK GLLNEPGQNS CFLNSAVQVS WMFDCFLQLL 60
ELQILICFLA CCMFCGVKAI FSQFQHSREK ALPSDNMRHA LAESFKDEQR FQLGFMDDAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCATGGG TGAAATTTCT AAGAAAACCT GGGGGTAACC TTGGAAAGGT TTATCAGCCT 60
GGAAGTATAT TGTCCCTGGC CCCTACAAAA GGCTTATTAA ATGAACCAGG ACAGAACAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0001508--P:action potential
GO:0051402--P:neuron apoptotic process
GO:0016579--P:protein deubiquitination
GO:0010996--P:response to auditory stimulus
GO:0007605--P:sensory perception of sound

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000820	Aegilops tauschii	25.79	2.00e-12	66.60
IUUC-Aml-002136	Ailuropoda melanoleuca	58.59	0.00e+00	1169.00
IUUC-Atr-002451	Amborella trichopoda	27.13	1.00e-31	132.00
IUUC-Apl-003843	Anas platyrhynchos	85.24	0.00e+00	1824.00
IUUC-Aca-004689	Anolis carolinensis	62.59	0.00e+00	1218.00
IUUC-Aly-005859	Arabidopsis lyrata	28.86	9.00e-32	132.00
IUUC-Ath-007147	Arabidopsis thaliana	30.12	6.00e-34	139.00
IUUC-Ame-010689	Astyanax mexicanus	46.46	3.00e-168	585.00
IUUC-Bta-012434	Bos taurus	57.38	0.00e+00	1131.00
IUUC-Bdi-015058	Brachypodium distachyon	29.29	5.00e-33	136.00
IUUC-Bol-015670	Brassica oleracea	27.62	2.00e-28	121.00
IUUC-Bra-016731	Brassica rapa	27.41	2.00e-30	128.00
IUUC-Cja-019625	Callithrix jacchus	59.23	0.00e+00	1159.00
IUUC-Cfa-020038	Canis familiaris	59.71	0.00e+00	1174.00
IUUC-Cpo-021503	Cavia porcellus	58.23	0.00e+00	1123.00
IUUC-Csa-024021	Chlorocebus sabaeus	59.91	0.00e+00	1155.00
IUUC-Cho-024769	Choloepus hoffmanni	67.54	0.00e+00	952.00
IUUC-Cin-025752	Ciona intestinalis	58.46	3.00e-42	162.00
IUUC-Csv-026063	Ciona savignyi	45.85	7.00e-83	300.00
IUUC-Dre-028438	Danio rerio	51.43	0.00e+00	654.00
IUUC-Dno-029317	Dasypus novemcinctus	57.04	0.00e+00	1097.00
IUUC-Dor-030249	Dipodomys ordii	85.41	0.00e+00	699.00
IUUC-Dme-032071	Drosophila melanogaster	44.10	7.00e-83	302.00
IUUC-Ete-032403	Echinops telfairi	58.72	0.00e+00	1135.00
IUUC-Eca-033216	Equus caballus	59.70	0.00e+00	1159.00
IUUC-Eeu-035319	Erinaceus europaeus	52.82	5.00e-136	478.00
IUUC-Fca-036414	Felis catus	57.44	0.00e+00	1145.00
IUUC-Fal-036886	Ficedula albicollis	79.96	0.00e+00	1710.00
IUUC-Gmo-038617	Gadus morhua	69.06	2.00e-155	541.00
IUUC-Gga-040930	Gallus gallus	91.07	0.00e+00	2000.00
IUUC-Gac-041515	Gasterosteus aculeatus	76.07	3.00e-158	550.00
IUUC-Gma-043691	Glycine max	27.71	3.00e-30	127.00
IUUC-Ggo-045573	Gorilla gorilla	59.87	0.00e+00	1147.00
IUUC-Hsa-046741	Homo sapiens	59.96	0.00e+00	1137.00
IUUC-Hvu-047657	Hordeum vulgare	30.18	1.00e-34	142.00
IUUC-Itr-048229	Ictidomys tridecemlineatus	51.20	0.00e+00	931.00
IUUC-Lch-049932	Latimeria chalumnae	58.82	0.00e+00	881.00
IUUC-Lpe-051572	Leersia perrieri	29.08	3.00e-32	134.00
IUUC-Loc-052180	Lepisosteus oculatus	50.77	0.00e+00	831.00
IUUC-Laf-054545	Loxodonta africana	60.32	0.00e+00	1181.00
IUUC-Mcc-054918	Macaca mulatta	59.63	0.00e+00	1161.00
IUUC-Meu-056802	Macropus eugenii	67.17	0.00e+00	925.00
IUUC-Mtr-058682	Medicago truncatula	26.26	2.00e-27	118.00
IUUC-Mmr-060991	Microcebus murinus	53.88	0.00e+00	825.00
IUUC-Mdo-062636	Monodelphis domestica	55.80	0.00e+00	1010.00
IUUC-Mmu-063910	Mus musculus	56.27	0.00e+00	1084.00
IUUC-Mac-064469	Musa acuminata	26.55	3.00e-11	64.70
IUUC-Mpu-065796	Mustela putorius furo	55.04	0.00e+00	1071.00
IUUC-Nle-069276	Nomascus leucogenys	59.31	0.00e+00	1076.00
IUUC-Opr-070545	Ochotona princeps	57.27	3.00e-172	598.00
IUUC-Ont-072449	Oreochromis niloticus	53.86	0.00e+00	684.00
IUUC-Oan-073493	Ornithorhynchus anatinus	56.33	0.00e+00	915.00
IUUC-Ocu-074445	Oryctolagus cuniculus	57.28	0.00e+00	1144.00
IUUC-Oba-075174	Oryza barthii	28.14	4.00e-29	124.00
IUUC-Obr-076268	Oryza brachyantha	29.28	5.00e-35	143.00
IUUC-Ogl-077138	Oryza glaberrima	29.20	2.00e-33	138.00
IUUC-Ogu-078705	Oryza glumaepatula	27.78	3.00e-29	124.00
IUUC-Oin-079125	Oryza indica	29.20	1.00e-33	138.00
IUUC-Olo-080872	Oryza longistaminata	28.14	2.00e-29	124.00
IUUC-Ome-081864	Oryza meridionalis	27.78	6.00e-29	124.00
IUUC-Oni-082109	Oryza nivara	27.78	3.00e-29	124.00
IUUC-Opu-083823	Oryza punctata	29.20	4.00e-34	140.00
IUUC-Oru-084310	Oryza rufipogon	27.78	3.00e-29	124.00
IUUC-Osa-085583	Oryza sativa	28.82	1.00e-33	137.00
IUUC-Ola-087574	Oryzias latipes	65.09	2.00e-148	518.00
IUUC-Oga-087977	Otolemur garnettii	56.69	0.00e+00	1043.00
IUUC-Oar-089584	Ovis aries	57.16	0.00e+00	1117.00
IUUC-Ptr-091610	Pan troglodytes	59.69	0.00e+00	1126.00
IUUC-Pan-091828	Papio anubis	56.68	0.00e+00	1040.00
IUUC-Psi-093643	Pelodiscus sinensis	69.44	0.00e+00	1443.00
IUUC-Ppa-095930	Physcomitrella patens	28.07	2.00e-34	141.00
IUUC-Pfo-096829	Poecilia formosa	60.46	1.00e-173	603.00
IUUC-Pab-098190	Pongo abelii	59.78	0.00e+00	1120.00
IUUC-Pop-099539	Populus trichocarpa	28.49	2.00e-28	121.00
IUUC-Ppe-101918	Prunus persica	28.07	3.00e-31	131.00
IUUC-Pva-102372	Pteropus vampyrus	55.81	0.00e+00	1050.00
IUUC-Rno-104919	Rattus norvegicus	84.00	5.00e-139	486.00
IUUC-Sha-107092	Sarcophilus harrisii	55.59	0.00e+00	1068.00
IUUC-Sit-110021	Setaria italica	28.53	6.00e-31	129.00
IUUC-Sly-110975	Solanum lycopersicum	27.60	1.00e-30	129.00
IUUC-Stu-112904	Solanum tuberosum	27.75	5.00e-28	120.00
IUUC-Sar-113376	Sorex araneus	51.48	5.00e-152	531.00
IUUC-Sbi-114345	Sorghum bicolor	29.33	1.00e-34	142.00
IUUC-Ssc-115969	Sus scrofa	60.41	0.00e+00	1109.00
IUUC-Tgu-117134	Taeniopygia guttata	89.64	0.00e+00	1342.00
IUUC-Tru-117981	Takifugu rubripes	63.98	2.00e-153	535.00
IUUC-Tsy-119297	Tarsius syrichta	51.60	0.00e+00	894.00
IUUC-Tni-120116	Tetraodon nigroviridis	72.53	4.00e-157	546.00
IUUC-Tca-121692	Theobroma cacao	28.36	2.00e-26	115.00
IUUC-Tae-125619	Triticum aestivum	29.59	2.00e-35	145.00
IUUC-Tur-126027	Triticum urartu	29.59	2.00e-35	144.00
IUUC-Tbe-127607	Tupaia belangeri	56.53	0.00e+00	1089.00
IUUC-Ttr-128647	Tursiops truncatus	61.11	0.00e+00	1041.00
IUUC-Vpa-130288	Vicugna pacos	55.38	0.00e+00	1057.00
IUUC-Vvi-131652	Vitis vinifera	27.27	7.00e-29	123.00
IUUC-Xtr-132277	Xenopus tropicalis	62.64	0.00e+00	875.00
IUUC-Xma-133162	Xiphophorus maculatus	68.36	9.00e-154	537.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence