iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000010336.1	ENSORLT00000012950.1	ENSORLP00000012949.1
ENSORLG00000010336.1	ENSORLT00000012954.1	ENSORLP00000012953.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.80e-74	250.6	89	419
ULD/UDP/UBQ/UBQ_Other	7.90e-08	32.4	980	1041

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp......kepkgellkslqklfeelwkskkkavsprellkalkkeaee 83
           +Gl+Nlg+tCY+N  LQ+ ++  elr+ l + ++++ +e +       + + ++++++lq lf+ l++s++k+++p+ l+kal+     
   Q: 89   VGLTNLGATCYVNTFLQVWFHNLELRRILYQCHNSRAQEHDTdtvspsDYDPQSISEHLQYLFALLQNSNRKYIDPSGLVKALG----- 172
           6******************************6666666655545555566777******************************9..... PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           +++ +qqDaqEf + +l+ le++l                       +++k+   +++i++ F gq+   ++c++c+++s   + f++l
   Q: 173  LDTGQQQDAQEFSKLFLSLLEDTL-----------------------SKQKNPNLHNVIQQQFCGQFFYVTVCNQCGRSSALPSRFYEL 238
           78899*******************.......................456788889********************************* PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l++ g++     +l++c+ +f kee+l+gen+y+ce+c++kq a++++kl++lP++L l+L+Rf f++++++++k+n+ ++fp++Ld+
   Q: 239  ELNILGHK-----NLTECITEFLKEEKLDGENRYFCESCQSKQSATRRIKLHSLPPTLNLQLMRFVFDRQTGHKKKLNTFISFPEQLDM 322
           ********.....9*************************************************************************** PP
   S: 262  spfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg..................... 327
           +pf++ +  +   k  YeL+av++H G s+ sGHY+a+vk+  +g+W++f+D+++++++ ++ +   +                     
   Q: 323  EPFLEARPGQ---KSVYELSAVLIHRGiSAYSGHYIAHVKDaLTGDWYKFNDEEIEKMEGKKLQLGIEediaeavkspsrkpkcskgyh 408
           ****995544...79**************************44666************999999866699******************* PP
   S: 328  ..staYvlfYk 336
             ++aY+l+Yk
   Q: 409  csRNAYMLVYK 419
           **********8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 13   ltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekk 73
             l v+   t +eLK +i +++++ p +q+L ++Gk L +d  tL+++g+ ++s i+l  ++
   Q: 980  KALIVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKSLtDDSATLGSLGVVPESIICLKADE 1041
           556689999********************************************999998776 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MAPRVQLEKA AWRWVEHVKP EEITQEHIEL AYRINLPACK RGACRRNCKG NPNCLVGIGE 60
QAWLGEIDEN TFHNIDDPNS ERRDKNTFVG LTNLGATCYV NTFLQVWFHN LELRRILYQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCGCAGAA ATTATGTATT TATAAATTGA CGCAAGCGCG CTAAATCTAA AACAAGCTGT 60
ACAAAAATGC CAAATTACAC AAGTGTGTGG ATAAAGTGGC GGCACTCATG AAAGGTTCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	28.85	3.00e-84	306.00
IUUC-Aml-001357	Ailuropoda melanoleuca	66.17	0.00e+00	1400.00
IUUC-Atr-002976	Amborella trichopoda	28.02	2.00e-89	323.00
IUUC-Apl-003773	Anas platyrhynchos	65.79	0.00e+00	1273.00
IUUC-Aca-004466	Anolis carolinensis	70.06	0.00e+00	758.00
IUUC-Aly-006249	Arabidopsis lyrata	28.55	4.00e-72	266.00
IUUC-Ath-006700	Arabidopsis thaliana	29.40	8.00e-82	298.00
IUUC-Ame-011554	Astyanax mexicanus	74.86	0.00e+00	1612.00
IUUC-Bta-012573	Bos taurus	66.17	0.00e+00	1415.00
IUUC-Bdi-014149	Brachypodium distachyon	27.83	6.00e-87	315.00
IUUC-Bol-016289	Brassica oleracea	29.69	2.00e-80	293.00
IUUC-Bra-017205	Brassica rapa	29.36	3.00e-72	266.00
IUUC-Cel-018662	Caenorhabditis elegans	31.07	4.00e-32	134.00
IUUC-Cja-019991	Callithrix jacchus	65.32	0.00e+00	1407.00
IUUC-Cfa-020294	Canis familiaris	66.42	0.00e+00	1430.00
IUUC-Cpo-021706	Cavia porcellus	65.79	0.00e+00	1348.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	32.09	4.00e-42	168.00
IUUC-Csa-023931	Chlorocebus sabaeus	66.45	0.00e+00	1423.00
IUUC-Cho-024566	Choloepus hoffmanni	61.69	2.00e-99	357.00
IUUC-Cin-025307	Ciona intestinalis	48.99	1.00e-79	289.00
IUUC-Csv-026006	Ciona savignyi	36.08	2.00e-156	546.00
IUUC-Cne-027065	Cryptococcus neoformans	29.06	4.00e-67	249.00
IUUC-Dre-027624	Danio rerio	75.14	0.00e+00	1640.00
IUUC-Dno-029633	Dasypus novemcinctus	68.96	0.00e+00	941.00
IUUC-Dor-030809	Dipodomys ordii	76.97	7.00e-155	541.00
IUUC-Ete-032818	Echinops telfairi	70.08	0.00e+00	729.00
IUUC-Eca-033692	Equus caballus	66.14	0.00e+00	1419.00
IUUC-Eeu-035185	Erinaceus europaeus	47.34	2.00e-138	486.00
IUUC-Fca-035676	Felis catus	66.11	0.00e+00	1424.00
IUUC-Fal-036913	Ficedula albicollis	66.20	0.00e+00	1422.00
IUUC-Gmo-038532	Gadus morhua	77.57	0.00e+00	1695.00
IUUC-Gga-041041	Gallus gallus	66.92	0.00e+00	1435.00
IUUC-Gac-042570	Gasterosteus aculeatus	84.12	0.00e+00	1854.00
IUUC-Gma-044136	Glycine max	29.79	3.00e-85	310.00
IUUC-Ggo-045367	Gorilla gorilla	63.56	0.00e+00	1329.00
IUUC-Hsa-046019	Homo sapiens	66.36	0.00e+00	1423.00
IUUC-Hvu-047303	Hordeum vulgare	36.85	6.00e-67	248.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	66.26	0.00e+00	1420.00
IUUC-Lch-049989	Latimeria chalumnae	67.35	0.00e+00	1466.00
IUUC-Lpe-051612	Leersia perrieri	27.40	2.00e-83	304.00
IUUC-Loc-052756	Lepisosteus oculatus	74.28	0.00e+00	1627.00
IUUC-Laf-054043	Loxodonta africana	66.57	0.00e+00	1436.00
IUUC-Mcc-054986	Macaca mulatta	65.35	0.00e+00	1407.00
IUUC-Meu-056228	Macropus eugenii	77.46	3.00e-161	562.00
IUUC-Mtr-058762	Medicago truncatula	33.18	2.00e-84	307.00
IUUC-Mga-059896	Meleagris gallopavo	65.99	0.00e+00	1344.00
IUUC-Mvi-060269	Microbotryum violaceum	38.97	2.00e-67	251.00
IUUC-Mmr-060887	Microcebus murinus	66.45	0.00e+00	1423.00
IUUC-Mdo-062506	Monodelphis domestica	66.88	0.00e+00	1435.00
IUUC-Mmu-063642	Mus musculus	66.64	0.00e+00	1433.00
IUUC-Mac-064896	Musa acuminata	28.73	6.00e-78	285.00
IUUC-Mpu-066194	Mustela putorius furo	66.29	0.00e+00	1424.00
IUUC-Mlu-067233	Myotis lucifugus	65.96	0.00e+00	1416.00
IUUC-Nle-069052	Nomascus leucogenys	65.62	0.00e+00	1407.00
IUUC-Opr-070890	Ochotona princeps	71.36	0.00e+00	923.00
IUUC-Ont-071450	Oreochromis niloticus	78.99	0.00e+00	1745.00
IUUC-Oan-073252	Ornithorhynchus anatinus	58.58	0.00e+00	687.00
IUUC-Ocu-073796	Oryctolagus cuniculus	65.67	0.00e+00	1217.00
IUUC-Oba-075563	Oryza barthii	27.88	1.00e-84	308.00
IUUC-Obr-076394	Oryza brachyantha	30.09	2.00e-81	297.00
IUUC-Ogl-077339	Oryza glaberrima	40.75	3.00e-43	168.00
IUUC-Ogu-079007	Oryza glumaepatula	27.38	1.00e-77	285.00
IUUC-Oin-079997	Oryza indica	27.88	9.00e-85	308.00
IUUC-Olo-080364	Oryza longistaminata	29.52	2.00e-82	300.00
IUUC-Ome-081165	Oryza meridionalis	27.36	7.00e-78	285.00
IUUC-Oni-083026	Oryza nivara	27.88	1.00e-84	308.00
IUUC-Opu-083284	Oryza punctata	27.70	8.00e-80	291.00
IUUC-Oru-084797	Oryza rufipogon	27.68	9.00e-85	308.00
IUUC-Osa-086221	Oryza sativa	40.75	3.00e-43	168.00
IUUC-Oga-088687	Otolemur garnettii	65.38	0.00e+00	1405.00
IUUC-Oar-090345	Ovis aries	65.99	0.00e+00	1348.00
IUUC-Ptr-090734	Pan troglodytes	66.36	0.00e+00	1424.00
IUUC-Pan-091704	Papio anubis	64.72	0.00e+00	1352.00
IUUC-Psi-092937	Pelodiscus sinensis	64.08	0.00e+00	1192.00
IUUC-Ppa-095808	Physcomitrella patens	30.38	2.00e-73	271.00
IUUC-Pab-098129	Pongo abelii	66.36	0.00e+00	1423.00
IUUC-Pop-099494	Populus trichocarpa	28.59	2.00e-77	284.00
IUUC-Pca-100647	Procavia capensis	76.06	2.00e-153	536.00
IUUC-Ppe-102091	Prunus persica	28.22	1.00e-86	314.00
IUUC-Pva-102719	Pteropus vampyrus	66.08	0.00e+00	1416.00
IUUC-Rno-105363	Rattus norvegicus	66.20	0.00e+00	1429.00
IUUC-Sha-107620	Sarcophilus harrisii	64.14	0.00e+00	1316.00
IUUC-Smo-109487	Selaginella moellendorffii	27.41	1.00e-84	307.00
IUUC-Sit-110683	Setaria italica	28.92	9.00e-84	305.00
IUUC-Sly-111377	Solanum lycopersicum	29.03	3.00e-76	280.00
IUUC-Stu-111969	Solanum tuberosum	31.41	4.00e-67	248.00
IUUC-Sar-113099	Sorex araneus	65.25	0.00e+00	1203.00
IUUC-Sbi-113833	Sorghum bicolor	44.59	2.00e-59	222.00
IUUC-Ssc-115279	Sus scrofa	57.50	0.00e+00	863.00
IUUC-Tgu-117519	Taeniopygia guttata	63.47	0.00e+00	1280.00
IUUC-Tru-117651	Takifugu rubripes	81.43	0.00e+00	1781.00
IUUC-Tsy-119201	Tarsius syrichta	64.07	0.00e+00	1268.00
IUUC-Tni-120840	Tetraodon nigroviridis	83.18	0.00e+00	1820.00
IUUC-Tca-121674	Theobroma cacao	28.26	2.00e-83	303.00
IUUC-Tae-125814	Triticum aestivum	29.71	4.00e-87	316.00
IUUC-Tur-126599	Triticum urartu	31.28	4.00e-81	296.00
IUUC-Tbe-127782	Tupaia belangeri	58.54	0.00e+00	1190.00
IUUC-Ttr-128312	Tursiops truncatus	65.27	0.00e+00	1395.00
IUUC-Vpa-130348	Vicugna pacos	65.66	0.00e+00	1341.00
IUUC-Vvi-131353	Vitis vinifera	26.43	2.00e-81	297.00
IUUC-Xtr-132172	Xenopus tropicalis	59.34	0.00e+00	1109.00
IUUC-Xma-133263	Xiphophorus maculatus	82.48	0.00e+00	1776.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence