iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044856

Ensembl Protein ID

ENSGGOP00000003025.2

UniProt Accession

G3QKP5; G3QKP5_GORGO

Protein Name

Uncharacterized protein

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000003073.2	ENSGGOT00000003093.2	ENSGGOP00000003025.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.30e-22	77.6	311	357

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 311  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 357
           8********988.6*******************.*******7.******5 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MEAATALHPG PRPALPLGGP GPLGEFLPPP ECPVFEPSWE ELSPPLPFPV KIKPFSSLIC 60
ICKIQHNVDW QPPFACDVDK LHFTPRIQRL NELEAQTRVK LNFLDQIAKY WELQGSTLKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCGG CCACCGCGCT GCACCCAGGC CCGCGCCCGG CGCTGCCTCT CGGGGGCCCG 60
GGCCCGCTGG GCGAGTTCCT GCCTCCACCC GAGTGCCCGG TCTTCGAACC CAGCTGGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001963	Ailuropoda melanoleuca	79.34	0.00e+00	2167.00
IUUC-Apl-003770	Anas platyrhynchos	67.92	0.00e+00	1618.00
IUUC-Aca-004867	Anolis carolinensis	66.40	0.00e+00	1885.00
IUUC-Ath-007218	Arabidopsis thaliana	35.56	3.00e-09	58.90
IUUC-Ame-010620	Astyanax mexicanus	50.69	0.00e+00	1398.00
IUUC-Bta-012733	Bos taurus	74.68	0.00e+00	2043.00
IUUC-Bol-015336	Brassica oleracea	36.45	2.00e-14	76.30
IUUC-Bra-017998	Brassica rapa	35.04	5.00e-13	71.60
IUUC-Cja-019050	Callithrix jacchus	80.39	0.00e+00	2271.00
IUUC-Cfa-021015	Canis familiaris	79.46	0.00e+00	2161.00
IUUC-Cpo-022340	Cavia porcellus	79.26	0.00e+00	2148.00
IUUC-Csa-023441	Chlorocebus sabaeus	81.09	0.00e+00	2241.00
IUUC-Cho-024823	Choloepus hoffmanni	81.48	0.00e+00	1338.00
IUUC-Dre-027707	Danio rerio	49.27	0.00e+00	1344.00
IUUC-Dno-028978	Dasypus novemcinctus	78.63	0.00e+00	2184.00
IUUC-Ete-032760	Echinops telfairi	69.31	0.00e+00	1313.00
IUUC-Eca-034370	Equus caballus	79.87	0.00e+00	2101.00
IUUC-Eeu-035012	Erinaceus europaeus	62.48	0.00e+00	728.00
IUUC-Fca-035494	Felis catus	80.20	0.00e+00	2163.00
IUUC-Fal-037631	Ficedula albicollis	67.83	0.00e+00	1837.00
IUUC-Gmo-039522	Gadus morhua	46.19	0.00e+00	1205.00
IUUC-Gga-040802	Gallus gallus	67.20	0.00e+00	1857.00
IUUC-Gac-041563	Gasterosteus aculeatus	49.49	0.00e+00	1334.00
IUUC-Hsa-045888	Homo sapiens	79.41	0.00e+00	2249.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	8.00e-16	79.30
IUUC-Itr-048297	Ictidomys tridecemlineatus	79.38	0.00e+00	2182.00
IUUC-Lch-050483	Latimeria chalumnae	54.30	0.00e+00	1510.00
IUUC-Loc-052550	Lepisosteus oculatus	56.37	0.00e+00	1553.00
IUUC-Laf-053761	Loxodonta africana	77.71	0.00e+00	2102.00
IUUC-Mcc-055505	Macaca mulatta	79.35	0.00e+00	2251.00
IUUC-Mga-059358	Meleagris gallopavo	67.38	0.00e+00	1871.00
IUUC-Mmr-060863	Microcebus murinus	79.33	0.00e+00	2204.00
IUUC-Mdo-061957	Monodelphis domestica	72.45	0.00e+00	2057.00
IUUC-Mmu-063944	Mus musculus	76.56	0.00e+00	2141.00
IUUC-Mac-065069	Musa acuminata	36.04	2.00e-08	56.20
IUUC-Mpu-066719	Mustela putorius furo	77.25	0.00e+00	2177.00
IUUC-Mlu-068086	Myotis lucifugus	71.72	0.00e+00	1947.00
IUUC-Nle-069256	Nomascus leucogenys	79.31	0.00e+00	2234.00
IUUC-Ont-071756	Oreochromis niloticus	49.62	0.00e+00	1378.00
IUUC-Oan-073568	Ornithorhynchus anatinus	73.12	0.00e+00	2064.00
IUUC-Ocu-073961	Oryctolagus cuniculus	75.39	0.00e+00	2109.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	9.00e-17	82.40
IUUC-Olo-080668	Oryza longistaminata	38.83	2.00e-16	82.00
IUUC-Osa-085487	Oryza sativa	38.83	9.00e-17	82.40
IUUC-Ola-086448	Oryzias latipes	49.36	0.00e+00	1337.00
IUUC-Oga-088501	Otolemur garnettii	74.34	0.00e+00	1779.00
IUUC-Oar-090162	Ovis aries	74.81	0.00e+00	2037.00
IUUC-Ptr-090816	Pan troglodytes	79.41	0.00e+00	2261.00
IUUC-Pan-092764	Papio anubis	81.22	0.00e+00	2245.00
IUUC-Psi-093918	Pelodiscus sinensis	65.81	0.00e+00	1644.00
IUUC-Pfo-096672	Poecilia formosa	49.28	0.00e+00	1332.00
IUUC-Pab-097854	Pongo abelii	75.52	0.00e+00	1645.00
IUUC-Pca-100241	Procavia capensis	73.80	0.00e+00	1401.00
IUUC-Pva-103035	Pteropus vampyrus	67.97	0.00e+00	1617.00
IUUC-Rno-105574	Rattus norvegicus	75.49	0.00e+00	2080.00
IUUC-Sha-106552	Sarcophilus harrisii	74.30	0.00e+00	833.00
IUUC-Sar-113477	Sorex araneus	73.34	0.00e+00	1850.00
IUUC-Ssc-116132	Sus scrofa	74.40	0.00e+00	1777.00
IUUC-Tgu-117452	Taeniopygia guttata	68.12	0.00e+00	1851.00
IUUC-Tsy-119271	Tarsius syrichta	73.95	0.00e+00	1558.00
IUUC-Tni-119650	Tetraodon nigroviridis	48.33	0.00e+00	1334.00
IUUC-Tbe-127890	Tupaia belangeri	77.09	0.00e+00	1270.00
IUUC-Ttr-128546	Tursiops truncatus	69.44	0.00e+00	1436.00
IUUC-Vpa-130432	Vicugna pacos	67.69	0.00e+00	1109.00
IUUC-Xtr-132008	Xenopus tropicalis	56.98	0.00e+00	1589.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence