iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089591

Ensembl Protein ID

ENSOARP00000001597.1

UniProt Accession

W5NTV3; W5NTV3_SHEEP

Genbank Protein ID

ENSOARP00000001597

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01063706

Gene Name

TRIM8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000001529.1	ENSOART00000001640.1	ENSOARP00000001597.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-07	32.5	15	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl  f + p+ lpC+H f++ C+ ++w     + s+  rCP C+
   Q: 15   CPICLHVFVE-PVQLPCKHNFCRGCIgEAW----AKDSGLVRCPECN 56
           ********99.999****************....889*********7 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAENWKNCFE EELICPICLH VFVEPVQLPC KHNFCRGCIG EAWAKDSGLV RCPECNQAYN 60
QKPGLEKNLK LTNIVEKFNA LHVEKPPAAL PRLRPPRPPP PAKSVLPRLG APPASPRGHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGGGG AGTTGGGCAG CCCTGCCCGG GGCCCCCGCC GGCGGCCGCC GCCATGGCGG 60
AGAATTGGAA GAACTGCTTT GAGGAGGAGC TCATCTGCCC GATCTGCCTG CACGTCTTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1900182--P:positive regulation of protein localization to nucleus
GO:0019827--P:stem cell population maintenance

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001258	Ailuropoda melanoleuca	89.08	0.00e+00	889.00
IUUC-Apl-004223	Anas platyrhynchos	77.97	0.00e+00	802.00
IUUC-Aca-005106	Anolis carolinensis	77.00	0.00e+00	800.00
IUUC-Ame-011348	Astyanax mexicanus	61.89	1.00e-175	609.00
IUUC-Bta-012787	Bos taurus	89.47	0.00e+00	893.00
IUUC-Cja-019471	Callithrix jacchus	89.28	0.00e+00	892.00
IUUC-Cfa-020052	Canis familiaris	89.08	0.00e+00	889.00
IUUC-Cpo-022491	Cavia porcellus	90.15	4.00e-169	587.00
IUUC-Csa-023544	Chlorocebus sabaeus	89.47	0.00e+00	893.00
IUUC-Dre-028013	Danio rerio	61.07	6.00e-174	603.00
IUUC-Dno-029676	Dasypus novemcinctus	88.69	0.00e+00	888.00
IUUC-Dor-030402	Dipodomys ordii	87.52	0.00e+00	875.00
IUUC-Ete-033188	Echinops telfairi	81.94	0.00e+00	806.00
IUUC-Eca-033524	Equus caballus	88.50	0.00e+00	878.00
IUUC-Eeu-034979	Erinaceus europaeus	88.26	7.00e-105	374.00
IUUC-Fca-036362	Felis catus	88.89	0.00e+00	884.00
IUUC-Fal-036652	Ficedula albicollis	76.01	0.00e+00	798.00
IUUC-Gmo-039405	Gadus morhua	55.21	2.00e-147	516.00
IUUC-Gga-040813	Gallus gallus	77.58	0.00e+00	800.00
IUUC-Gac-041792	Gasterosteus aculeatus	58.09	7.00e-145	507.00
IUUC-Ggo-044962	Gorilla gorilla	89.08	0.00e+00	890.00
IUUC-Hsa-046158	Homo sapiens	88.89	0.00e+00	887.00
IUUC-Itr-048118	Ictidomys tridecemlineatus	89.08	0.00e+00	888.00
IUUC-Lch-049433	Latimeria chalumnae	71.88	0.00e+00	707.00
IUUC-Loc-052026	Lepisosteus oculatus	69.94	0.00e+00	694.00
IUUC-Laf-054159	Loxodonta africana	91.75	0.00e+00	722.00
IUUC-Mcc-055490	Macaca mulatta	89.47	0.00e+00	893.00
IUUC-Meu-056549	Macropus eugenii	85.87	0.00e+00	638.00
IUUC-Mga-059334	Meleagris gallopavo	77.58	0.00e+00	793.00
IUUC-Mmr-061672	Microcebus murinus	89.28	0.00e+00	891.00
IUUC-Mdo-061849	Monodelphis domestica	79.69	0.00e+00	709.00
IUUC-Mmu-063537	Mus musculus	87.91	0.00e+00	882.00
IUUC-Mpu-065762	Mustela putorius furo	89.08	0.00e+00	889.00
IUUC-Mlu-066979	Myotis lucifugus	89.43	4.00e-180	623.00
IUUC-Nle-069419	Nomascus leucogenys	89.08	0.00e+00	890.00
IUUC-Opr-070981	Ochotona princeps	88.30	0.00e+00	883.00
IUUC-Ont-072053	Oreochromis niloticus	60.82	6.00e-120	424.00
IUUC-Oan-073608	Ornithorhynchus anatinus	81.70	0.00e+00	655.00
IUUC-Ocu-074694	Oryctolagus cuniculus	87.91	0.00e+00	872.00
IUUC-Ola-086949	Oryzias latipes	53.99	2.00e-138	485.00
IUUC-Oga-089175	Otolemur garnettii	89.08	0.00e+00	890.00
IUUC-Ptr-091309	Pan troglodytes	87.91	0.00e+00	855.00
IUUC-Pan-091903	Papio anubis	89.47	0.00e+00	893.00
IUUC-Psi-093293	Pelodiscus sinensis	75.24	0.00e+00	757.00
IUUC-Pfo-097191	Poecilia formosa	53.60	7.00e-133	467.00
IUUC-Pab-098251	Pongo abelii	85.19	0.00e+00	837.00
IUUC-Pca-100504	Procavia capensis	89.08	0.00e+00	890.00
IUUC-Pva-102320	Pteropus vampyrus	87.72	0.00e+00	868.00
IUUC-Rno-105545	Rattus norvegicus	88.50	0.00e+00	886.00
IUUC-Ssc-116121	Sus scrofa	89.47	0.00e+00	893.00
IUUC-Tgu-116724	Taeniopygia guttata	77.58	0.00e+00	793.00
IUUC-Tru-118048	Takifugu rubripes	61.13	5.00e-124	437.00
IUUC-Tni-120856	Tetraodon nigroviridis	54.86	4.00e-137	481.00
IUUC-Tbe-127400	Tupaia belangeri	90.79	3.00e-157	547.00
IUUC-Ttr-128233	Tursiops truncatus	88.50	0.00e+00	870.00
IUUC-Xtr-132578	Xenopus tropicalis	75.78	0.00e+00	778.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence