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Tag Content
iUUCD ID IUUC-Ani-009303
Ensembl Protein ID CADANIAP00008806
UniProt Accession Q5BBF1; C8VM14; Q4L2Q0; CSN5_EMENI
Genbank Protein ID AAM95164.1; EAA64961.1; CBF86237.1
Protein Name COP9 signalosome complex subunit 5
Genbank Nucleotide ID AY126455; AACD01000032; BN001307
Gene Name csnE; rri1; csn5; AN2129
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
CADANIAG00008806 CADANIAT00008806 CADANIAP00008806
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/JAMM 5.10e-08 31.9 134 147
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/JAMM
   S: 1    HSHPgftcwlSsVD 14
           HSHPg++cwlS++D
   Q: 134  HSHPGYGCWLSGID 147
           *************9 PP
   
Organism Aspergillus nidulans
Functional Description
(View)

Functional Description


     Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity). The CSN complex seems to link protein degradation to sexual development. Required for fruit body formation.
 Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity). The CSN complex seems to link protein degradation to sexual development. Required for fruit body formation.
Protein Sequence
(Fasta)
MQAAQLSWEL ENAVTLIDPQ RDSLYRYDEE THKYLSDTRP WTKDPHYFKS VRISAVALLK 60
MVMHARSGGS LEVMGLMQGY ILPNTFVVTD AFRLPVEGTE TRVNAQDEAN EYMVSYLQSC 120
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Protein Fasta Sequence


>IUUC-Ani-009303|DUB,JAMM|Aspergillus nidulans
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Nucleotide Sequence
(Fasta)
ATGCAAGCTG CTCAACTATC CTGGGGTTAG TAATGAGGTC TTTCAGTTTA TGATCCACTG 60
ATGCTTACGT CTCGTAGAGC TAGAGAATGC TGTTACCCTG ATTGATCCCC AACGAGACTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ani-009303|DUB,JAMM|Aspergillus nidulans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0482--Metalloprotease
KW-0539--Nucleus
KW-0645--Protease
KW-1185--Reference proteome
KW-0736--Signalosome
KW-0862--Zinc
Interpro

IPR000555--JAMM/MPN+_dom
Pfam

PF01398--JAB
SMART

SM00232--JAB_MPN
Gene Ontology

GO:0008180--C:COP9 signalosome
GO:0005737--C:cytoplasm
GO:0046872--F:metal ion binding
GO:0004222--F:metalloendopeptidase activity
GO:0070791--P:cleistothecium development
GO:0030448--P:hyphal growth
GO:0000338--P:protein deneddylation
GO:0045116--P:protein neddylation
KEGG ani:AN2129.2
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000468 Aegilops tauschii 53.78 6.00e-97 345.00
IUUC-Aml-001429 Ailuropoda melanoleuca 54.60 2.00e-91 327.00
IUUC-Atr-003048 Amborella trichopoda 54.49 1.00e-99 354.00
IUUC-Apl-003610 Anas platyrhynchos 55.41 1.00e-87 314.00
IUUC-Aca-004662 Anolis carolinensis 56.60 3.00e-83 299.00
IUUC-Aly-005914 Arabidopsis lyrata 52.63 2.00e-97 347.00
IUUC-Ath-007496 Arabidopsis thaliana 53.92 2.00e-99 354.00
IUUC-Ago-007860 Ashbya gossypii 47.34 3.00e-49 187.00
IUUC-Acl-008155 Aspergillus clavatus 83.88 2.00e-173 599.00
IUUC-Afu-008820 Aspergillus fumigatus 85.24 2.00e-173 599.00
IUUC-Ang-009617 Aspergillus niger 86.08 8.00e-166 574.00
IUUC-Aor-009888 Aspergillus oryzae 88.65 6.00e-178 614.00
IUUC-Ate-010575 Aspergillus terreus 88.59 0.00e+00 625.00
IUUC-Ame-010617 Astyanax mexicanus 53.99 1.00e-92 330.00
IUUC-Bgr-012019 Blumeria graminis 65.15 6.00e-127 444.00
IUUC-Bta-013211 Bos taurus 54.74 3.00e-92 329.00
IUUC-Bci-013645 Botrytis cinerea 67.58 5.00e-132 461.00
IUUC-Bdi-014727 Brachypodium distachyon 53.92 3.00e-92 329.00
IUUC-Bol-015205 Brassica oleracea 51.96 3.00e-93 333.00
IUUC-Bra-017649 Brassica rapa 51.96 3.00e-93 333.00
IUUC-Cel-018469 Caenorhabditis elegans 51.56 1.00e-94 338.00
IUUC-Cja-019703 Callithrix jacchus 54.74 3.00e-92 329.00
IUUC-Cfa-020181 Canis familiaris 54.74 3.00e-92 329.00
IUUC-Cpo-021499 Cavia porcellus 54.74 3.00e-92 329.00
IUUC-Cre-022735 Chlamydomonas reinhardtii 52.17 7.00e-99 351.00
IUUC-Csa-024200 Chlorocebus sabaeus 54.74 3.00e-92 329.00
IUUC-Cho-024915 Choloepus hoffmanni 55.12 4.00e-60 223.00
IUUC-Cin-025353 Ciona intestinalis 51.86 1.00e-85 308.00
IUUC-Csv-026118 Ciona savignyi 52.01 2.00e-86 310.00
IUUC-Cgl-026511 Colletotrichum gloeosporioides 60.12 6.00e-119 418.00
IUUC-Cne-026988 Cryptococcus neoformans 54.65 2.00e-81 293.00
IUUC-Dre-028134 Danio rerio 53.68 6.00e-92 328.00
IUUC-Dno-029658 Dasypus novemcinctus 54.74 3.00e-92 329.00
IUUC-Dor-031074 Dipodomys ordii 54.74 3.00e-92 329.00
IUUC-Dse-031497 Dothistroma septosporum 59.27 1.00e-114 404.00
IUUC-Dme-032199 Drosophila melanogaster 56.06 6.00e-101 358.00
IUUC-Ete-032739 Echinops telfairi 60.74 5.00e-49 186.00
IUUC-Eca-034095 Equus caballus 54.74 3.00e-92 330.00
IUUC-Eeu-034934 Erinaceus europaeus 63.37 3.00e-84 303.00
IUUC-Fca-035569 Felis catus 54.74 3.00e-92 329.00
IUUC-Fal-037553 Ficedula albicollis 57.04 3.00e-83 299.00
IUUC-Fox-037945 Fusarium oxysporum 59.28 7.00e-118 414.00
IUUC-Fso-038385 Fusarium solani 61.88 8.00e-124 434.00
IUUC-Gmo-039438 Gadus morhua 53.37 3.00e-90 323.00
IUUC-Ggr-039968 Gaeumannomyces graminis 58.36 3.00e-119 419.00
IUUC-Gga-040344 Gallus gallus 54.29 6.00e-91 325.00
IUUC-Gac-042256 Gasterosteus aculeatus 54.29 4.00e-91 326.00
IUUC-Gma-043226 Glycine max 52.62 7.00e-95 338.00
IUUC-Ggo-044523 Gorilla gorilla 50.15 1.00e-79 287.00
IUUC-Hsa-046659 Homo sapiens 54.74 3.00e-92 329.00
IUUC-Itr-048834 Ictidomys tridecemlineatus 54.74 3.00e-92 329.00
IUUC-Kpa-049139 Komagataella pastoris 59.12 2.00e-57 214.00
IUUC-Lch-049562 Latimeria chalumnae 54.60 1.00e-92 331.00
IUUC-Lpe-050737 Leersia perrieri 53.92 4.00e-98 349.00
IUUC-Loc-051798 Lepisosteus oculatus 54.15 2.00e-90 324.00
IUUC-Lma-052979 Leptosphaeria maculans 59.59 5.00e-115 405.00
IUUC-Laf-053391 Loxodonta africana 62.62 5.00e-71 258.00
IUUC-Mcc-055667 Macaca mulatta 54.74 3.00e-92 329.00
IUUC-Meu-056067 Macropus eugenii 70.69 7.00e-20 89.00
IUUC-Mor-057084 Magnaporthe oryzae 61.13 2.00e-120 423.00
IUUC-Mpo-057347 Magnaporthe poae 62.54 4.00e-123 432.00
IUUC-Mtr-057781 Medicago truncatula 54.38 6.00e-98 348.00
IUUC-Mla-059106 Melampsora laricipopulina 52.31 2.00e-99 353.00
IUUC-Mga-059473 Meleagris gallopavo 57.04 3.00e-83 299.00
IUUC-Mvi-060540 Microbotryum violaceum 49.86 4.00e-98 349.00
IUUC-Mmr-061138 Microcebus murinus 66.84 4.00e-66 242.00
IUUC-Mdo-062893 Monodelphis domestica 55.05 1.00e-92 330.00
IUUC-Mmu-063637 Mus musculus 54.74 3.00e-92 329.00
IUUC-Mac-064683 Musa acuminata 56.13 2.00e-100 357.00
IUUC-Mpu-066096 Mustela putorius furo 50.91 9.00e-77 278.00
IUUC-Mlu-067872 Myotis lucifugus 53.82 3.00e-89 320.00
IUUC-Nfi-068443 Neosartorya fischeri 85.54 8.00e-174 600.00
IUUC-Ncr-068953 Neurospora crassa 58.07 1.00e-111 394.00
IUUC-Nle-068972 Nomascus leucogenys 54.74 3.00e-92 329.00
IUUC-Opr-070215 Ochotona princeps 49.69 9.00e-78 281.00
IUUC-Ont-072538 Oreochromis niloticus 54.29 3.00e-91 326.00
IUUC-Oan-073143 Ornithorhynchus anatinus 55.05 2.00e-92 330.00
IUUC-Ocu-074197 Oryctolagus cuniculus 54.74 3.00e-92 329.00
IUUC-Oba-075884 Oryza barthii 49.72 3.00e-92 330.00
IUUC-Obr-076874 Oryza brachyantha 54.05 9.00e-98 348.00
IUUC-Ogl-077169 Oryza glaberrima 53.78 1.00e-96 344.00
IUUC-Ogu-078258 Oryza glumaepatula 53.78 1.00e-96 344.00
IUUC-Oin-079101 Oryza indica 50.00 1.00e-92 331.00
IUUC-Olo-080708 Oryza longistaminata 50.55 3.00e-69 253.00
IUUC-Ome-081571 Oryza meridionalis 50.00 1.00e-92 331.00
IUUC-Oni-082888 Oryza nivara 50.00 1.00e-92 331.00
IUUC-Opu-083182 Oryza punctata 53.78 1.00e-96 344.00
IUUC-Oru-084895 Oryza rufipogon 50.00 1.00e-92 331.00
IUUC-Osa-085331 Oryza sativa 53.78 1.00e-96 344.00
IUUC-Ola-086850 Oryzias latipes 54.29 2.00e-91 327.00
IUUC-Olu-087607 Ostreococcus lucimarinus 58.54 2.00e-84 303.00
IUUC-Oga-088640 Otolemur garnettii 54.60 1.00e-91 327.00
IUUC-Oar-090299 Ovis aries 54.60 2.00e-91 327.00
IUUC-Ptr-091499 Pan troglodytes 54.74 3.00e-92 329.00
IUUC-Pan-091751 Papio anubis 57.39 4.00e-83 299.00
IUUC-Psi-092978 Pelodiscus sinensis 54.29 6.00e-91 325.00
IUUC-Pma-094634 Petromyzon marinus 53.47 4.00e-91 326.00
IUUC-Pno-095094 Phaeosphaeria nodorum 60.60 8.00e-116 408.00
IUUC-Ppa-095440 Physcomitrella patens 53.29 3.00e-100 356.00
IUUC-Pfo-097332 Poecilia formosa 54.29 7.00e-91 325.00
IUUC-Pab-097998 Pongo abelii 54.74 3.00e-92 329.00
IUUC-Pop-098905 Populus trichocarpa 52.65 6.00e-102 362.00
IUUC-Ppe-101309 Prunus persica 53.37 2.00e-104 370.00
IUUC-Pva-102953 Pteropus vampyrus 54.74 3.00e-92 329.00
IUUC-Pgr-103452 Puccinia graminis 60.15 1.00e-90 324.00
IUUC-Ptt-103777 Puccinia triticina 61.60 5.00e-89 319.00
IUUC-Pte-104273 Pyrenophora teres 58.88 2.00e-114 404.00
IUUC-Pyt-104627 Pyrenophora triticirepentis 59.94 1.00e-114 404.00
IUUC-Rno-105666 Rattus norvegicus 54.74 1.00e-91 328.00
IUUC-Sce-106319 Saccharomyces cerevisiae 37.50 1.00e-36 145.00
IUUC-Sha-106602 Sarcophilus harrisii 55.05 1.00e-92 330.00
IUUC-Sja-107822 Schizosaccharomyces japonicus 44.55 8.00e-47 178.00
IUUC-Spo-108318 Schizosaccharomyces pombe 42.97 4.00e-62 229.00
IUUC-Ssl-108428 Sclerotinia sclerotiorum 67.27 1.00e-131 460.00
IUUC-Smo-108821 Selaginella moellendorffii 55.19 3.00e-101 360.00
IUUC-Sit-110526 Setaria italica 57.29 1.00e-92 331.00
IUUC-Sly-110851 Solanum lycopersicum 53.98 2.00e-103 367.00
IUUC-Stu-112776 Solanum tuberosum 52.87 2.00e-103 367.00
IUUC-Sar-113459 Sorex araneus 54.74 3.00e-92 330.00
IUUC-Sbi-114873 Sorghum bicolor 54.05 3.00e-97 346.00
IUUC-Sre-114919 Sporisorium reilianum 63.30 1.00e-93 335.00
IUUC-Ssc-116102 Sus scrofa 54.74 3.00e-92 329.00
IUUC-Tgu-116937 Taeniopygia guttata 67.11 4.00e-80 288.00
IUUC-Tru-118615 Takifugu rubripes 54.29 6.00e-91 325.00
IUUC-Tsy-119173 Tarsius syrichta 62.31 9.00e-89 318.00
IUUC-Tni-120246 Tetraodon nigroviridis 54.29 6.00e-91 325.00
IUUC-Tca-121859 Theobroma cacao 54.10 1.00e-103 367.00
IUUC-Tre-122030 Trichoderma reesei 60.54 1.00e-119 421.00
IUUC-Tvi-122506 Trichoderma virens 59.64 2.00e-117 413.00
IUUC-Tae-125382 Triticum aestivum 53.47 3.00e-96 343.00
IUUC-Tur-126517 Triticum urartu 55.16 1.00e-95 340.00
IUUC-Tme-127122 Tuber melanosporum 59.52 1.00e-116 411.00
IUUC-Tbe-128108 Tupaia belangeri 54.43 3.00e-89 320.00
IUUC-Ttr-128644 Tursiops truncatus 54.74 3.00e-92 329.00
IUUC-Uma-129390 Ustilago maydis 58.74 8.00e-90 322.00
IUUC-Vda-129932 Verticillium dahliae 57.88 8.00e-115 405.00
IUUC-Vpa-130110 Vicugna pacos 54.74 3.00e-92 329.00
IUUC-Vvi-131534 Vitis vinifera 53.45 2.00e-100 357.00
IUUC-Xtr-132739 Xenopus tropicalis 53.99 4.00e-92 329.00
IUUC-Xma-133919 Xiphophorus maculatus 54.29 6.00e-91 325.00
IUUC-Yli-134677 Yarrowia lipolytica 52.72 8.00e-104 368.00
IUUC-Zma-135578 Zea mays 53.75 2.00e-96 343.00
Created Date 25-Jun-2017

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