iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049507

Ensembl Protein ID

ENSLACP00000008685.1

UniProt Accession

H3AGB4; H3AGB4_LATCH

Genbank Protein ID

ENSLACP00000008685

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01152109

Gene Name

WDR48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000007679.1	ENSLACT00000008753.1	ENSLACP00000008685.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-32	110.9	208	245
UBD/Beta-Prp	1.10e-47	162.9	30	310
ULD/UBL/SUMO	1.10e-61	205.8	559	666
ULD/UDP/UFD/RAWUL	1.40e-23	83.4	568	673

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHtd v +l +  d t  +sGs Dgti++W+l +++++
   Q: 208  GHTDNVKALLLnRDgTQCLSGSSDGTIRLWSLGQQRCI 245
           8********88*888*****************999997 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkl...lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghed 95
            + +++++  p  + l+t++rd+ i++w+v + k    ++s++ h++ v+++ +  +gk+l+++s+D t+kvw+  +g c++tl+ h+d
   Q: 30   RNGVNALQLDPALNRLFTAGRDSIIRIWSVGQHKQdpyIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKD 118
           556677888899999*****************999999*************************************************** PP
   S: 96   svlslsfspsgdklvsGshdrtirvwdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           +v +l++ ++++ ++s++ dr i +wd++t + l +         lsg+++++ ++++++ g ++vsGs+ +++r+Wd +t   l +l+
   Q: 119  YVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTAsnntvttsSLSGNKDSIYSLAMNQMGTVIVSGSTEKVLRVWDPRTCAKLMKLK 207
           **********************************99*********************************************99999**9 PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn. 264
           g htd v+ l ++++g++++sgs dgt++lw+l +++c+ t++ h++ v+ +++ +  ++++sg+ D+ i++ dlr+ d+   +  ++ 
   Q: 208  G-HTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNEAFTHVYSGGRDRKIYCTDLRNPDIRLLICEEKa 295
           9.**************************************************************************9999888888774 PP
   S: 265  ..............s 265
                          
   Q: 296  pvlkmeldrsadppP 310
           555544444444441 PP

ULD/UBL/SUMO

   S: 1    eskffkapvslkvagqdGsevlfklklsa....qlkklmeavYvkrinldensvrfv.fngqkireqetpeelevededkiellcq... 81
           ++kf+k+p++l++++++G+++l+k++lsa    q++k+me+vY+k+inld++s++++ +n++k +eqe++e+++v++e+kiellcq   
   Q: 559  MPKFNKIPFYLQPHSSSGAKTLKKDRLSAsdmlQVRKVMEHVYEKIINLDNESQTTSsSNNEKQGEQEKEEDIAVLAEEKIELLCQdqv 647
           8********************************************************9****************************777 PP
   S: 82   ...............ksGG 85
                          ksGG
   Q: 648  ldpnmdlrtvkhfiwKSGG 666
           7777777777777777776 PP

ULD/UDP/UFD/RAWUL

   S: 4    sLeplesnkakddsklkkkylrcsarltVkhlkkflaeklkl........sssy.....................evdllcedevLedn 63
            L+p++s++ak+   lkk++l++s++l+V++++++++ek+++        s                        +++llc+d+vL++n
   Q: 568  YLQPHSSSGAKT---LKKDRLSASDMLQVRKVMEHVYEKIINldnesqttS--SsnnekqgeqekeediavlaeeKIELLCQDQVLDPN 651
           69**********...*************************99988766653..045799999999************************ PP
   S: 64   etLeeikyifiwkkegpLvLqYr 86
           ++L+++ ++fiwk++g+L+L+Yr
   Q: 652  MDLRTV-KHFIWKSGGDLTLHYR 673
           ******.***************9 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MAAHHRQNAA GRRKVQVSYV IRDEVEKYNR NGVNALQLDP ALNRLFTAGR DSIIRIWSVG 60
QHKQDPYIAS MEHHTDWVND IVLCCNGKTL ISASSDTTVK VWNAHKGFCM STLRTHKDYV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTCTTGCA CGCAAACTAG GTCCCTCTAC AACAAAAAAA AGAAAAACGC TTACTGGGTC 60
TAATGGTCTT TTCCTGTTCC TAAATTTTCT TATGTAGTGA TCTCAAAACC GGGTTCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR021772--DUF3337
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF11816--DUF3337
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

KEGG

lcm:102346929

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001160	Aegilops tauschii	39.49	9.00e-96	344.00
IUUC-Aml-001533	Ailuropoda melanoleuca	97.05	0.00e+00	1231.00
IUUC-Atr-003009	Amborella trichopoda	33.86	3.00e-109	389.00
IUUC-Apl-003709	Anas platyrhynchos	96.79	0.00e+00	652.00
IUUC-Aca-004875	Anolis carolinensis	97.49	0.00e+00	1272.00
IUUC-Aly-005464	Arabidopsis lyrata	39.45	2.00e-92	333.00
IUUC-Ath-006969	Arabidopsis thaliana	39.25	1.00e-88	320.00
IUUC-Acl-008203	Aspergillus clavatus	35.40	2.00e-47	184.00
IUUC-Afl-008571	Aspergillus flavus	36.23	9.00e-47	182.00
IUUC-Afu-009072	Aspergillus fumigatus	35.93	5.00e-46	179.00
IUUC-Ani-009413	Aspergillus nidulans	36.59	4.00e-48	186.00
IUUC-Ang-009571	Aspergillus niger	35.33	1.00e-44	175.00
IUUC-Aor-010064	Aspergillus oryzae	36.23	4.00e-47	183.00
IUUC-Ate-010463	Aspergillus terreus	35.93	3.00e-47	183.00
IUUC-Ame-010875	Astyanax mexicanus	95.22	0.00e+00	1077.00
IUUC-Bgr-012288	Blumeria graminis	33.33	4.00e-41	163.00
IUUC-Bta-013379	Bos taurus	96.90	0.00e+00	1229.00
IUUC-Bci-013859	Botrytis cinerea	32.01	9.00e-41	162.00
IUUC-Bdi-014645	Brachypodium distachyon	34.33	2.00e-110	393.00
IUUC-Bol-016450	Brassica oleracea	34.31	6.00e-98	352.00
IUUC-Bra-017237	Brassica rapa	34.24	3.00e-100	359.00
IUUC-Cel-018656	Caenorhabditis elegans	44.60	3.00e-155	541.00
IUUC-Cja-018804	Callithrix jacchus	96.90	0.00e+00	1226.00
IUUC-Cfa-020076	Canis familiaris	97.05	0.00e+00	1231.00
IUUC-Cpo-021721	Cavia porcellus	95.77	0.00e+00	1186.00
IUUC-Cre-022779	Chlamydomonas reinhardtii	30.45	8.00e-39	156.00
IUUC-Csa-023188	Chlorocebus sabaeus	97.05	0.00e+00	1231.00
IUUC-Cho-024932	Choloepus hoffmanni	95.86	0.00e+00	1233.00
IUUC-Cin-025591	Ciona intestinalis	56.28	0.00e+00	715.00
IUUC-Cgl-026540	Colletotrichum gloeosporioides	27.86	6.00e-21	96.30
IUUC-Cne-026819	Cryptococcus neoformans	35.53	1.00e-34	142.00
IUUC-Cme-027188	Cyanidioschyzon merolae	31.98	8.00e-70	258.00
IUUC-Dre-027926	Danio rerio	93.35	0.00e+00	1253.00
IUUC-Dno-029960	Dasypus novemcinctus	96.45	0.00e+00	1222.00
IUUC-Dor-030933	Dipodomys ordii	92.02	0.00e+00	696.00
IUUC-Dse-031532	Dothistroma septosporum	34.78	9.00e-45	175.00
IUUC-Dme-032168	Drosophila melanogaster	56.68	0.00e+00	683.00
IUUC-Ete-033107	Echinops telfairi	93.21	0.00e+00	1161.00
IUUC-Eca-034028	Equus caballus	97.19	0.00e+00	1232.00
IUUC-Eeu-034894	Erinaceus europaeus	93.45	0.00e+00	825.00
IUUC-Fca-035619	Felis catus	96.54	0.00e+00	929.00
IUUC-Fal-036869	Ficedula albicollis	97.58	0.00e+00	1239.00
IUUC-Fox-037907	Fusarium oxysporum	33.05	1.00e-40	161.00
IUUC-Fso-038101	Fusarium solani	32.96	2.00e-40	160.00
IUUC-Gmo-038627	Gadus morhua	95.42	0.00e+00	1274.00
IUUC-Ggr-039995	Gaeumannomyces graminis	31.01	2.00e-41	164.00
IUUC-Gga-040555	Gallus gallus	97.64	0.00e+00	1268.00
IUUC-Gac-042497	Gasterosteus aculeatus	95.42	0.00e+00	1249.00
IUUC-Gma-043089	Glycine max	34.43	5.00e-108	385.00
IUUC-Ggo-045561	Gorilla gorilla	97.05	0.00e+00	1231.00
IUUC-Hsa-045710	Homo sapiens	97.05	0.00e+00	1231.00
IUUC-Hvu-047730	Hordeum vulgare	35.06	1.00e-82	300.00
IUUC-Itr-049030	Ictidomys tridecemlineatus	96.62	0.00e+00	862.00
IUUC-Kpa-049237	Komagataella pastoris	30.46	3.00e-29	124.00
IUUC-Lpe-051608	Leersia perrieri	34.52	1.00e-108	387.00
IUUC-Loc-052373	Lepisosteus oculatus	94.70	0.00e+00	1235.00
IUUC-Lma-053025	Leptosphaeria maculans	35.54	1.00e-47	185.00
IUUC-Laf-053706	Loxodonta africana	96.53	0.00e+00	1194.00
IUUC-Mcc-055046	Macaca mulatta	97.05	0.00e+00	1231.00
IUUC-Meu-056840	Macropus eugenii	78.61	1.00e-146	513.00
IUUC-Mor-057284	Magnaporthe oryzae	32.33	1.00e-41	165.00
IUUC-Mpo-057418	Magnaporthe poae	31.01	5.00e-41	163.00
IUUC-Mtr-058571	Medicago truncatula	34.47	5.00e-107	382.00
IUUC-Mla-059101	Melampsora laricipopulina	44.61	1.00e-45	179.00
IUUC-Mga-059297	Meleagris gallopavo	97.64	0.00e+00	1268.00
IUUC-Mvi-060419	Microbotryum violaceum	41.10	3.00e-38	154.00
IUUC-Mmr-061196	Microcebus murinus	90.32	0.00e+00	1109.00
IUUC-Mdo-062762	Monodelphis domestica	93.47	0.00e+00	1251.00
IUUC-Mmu-063915	Mus musculus	95.57	0.00e+00	1251.00
IUUC-Mac-065434	Musa acuminata	34.42	1.00e-104	374.00
IUUC-Mpu-065999	Mustela putorius furo	96.26	0.00e+00	824.00
IUUC-Mlu-068226	Myotis lucifugus	96.60	0.00e+00	1224.00
IUUC-Nfi-068416	Neosartorya fischeri	29.94	3.00e-56	213.00
IUUC-Ncr-068825	Neurospora crassa	30.77	1.00e-38	155.00
IUUC-Nle-069416	Nomascus leucogenys	97.05	0.00e+00	1231.00
IUUC-Opr-070515	Ochotona princeps	92.91	0.00e+00	1158.00
IUUC-Ont-072052	Oreochromis niloticus	92.95	0.00e+00	1187.00
IUUC-Oan-073636	Ornithorhynchus anatinus	93.66	0.00e+00	1221.00
IUUC-Ocu-074799	Oryctolagus cuniculus	96.90	0.00e+00	1228.00
IUUC-Oba-075146	Oryza barthii	34.52	4.00e-109	389.00
IUUC-Obr-076699	Oryza brachyantha	34.38	2.00e-109	389.00
IUUC-Ogl-077883	Oryza glaberrima	32.86	3.00e-65	242.00
IUUC-Ogu-078114	Oryza glumaepatula	34.76	6.00e-108	384.00
IUUC-Oin-079575	Oryza indica	34.55	9.00e-112	397.00
IUUC-Olo-080531	Oryza longistaminata	32.14	5.00e-98	352.00
IUUC-Ome-081368	Oryza meridionalis	39.73	6.00e-97	348.00
IUUC-Oni-082457	Oryza nivara	34.52	5.00e-109	388.00
IUUC-Opu-084050	Oryza punctata	34.39	5.00e-108	385.00
IUUC-Oru-084330	Oryza rufipogon	34.52	5.00e-109	388.00
IUUC-Osa-085408	Oryza sativa	34.55	9.00e-112	397.00
IUUC-Ola-087546	Oryzias latipes	94.88	0.00e+00	1251.00
IUUC-Olu-087710	Ostreococcus lucimarinus	30.79	1.00e-78	287.00
IUUC-Oga-087998	Otolemur garnettii	95.84	0.00e+00	1205.00
IUUC-Oar-090303	Ovis aries	96.90	0.00e+00	1229.00
IUUC-Ptr-090588	Pan troglodytes	97.05	0.00e+00	1231.00
IUUC-Pan-092722	Papio anubis	97.05	0.00e+00	1231.00
IUUC-Psi-093911	Pelodiscus sinensis	97.07	0.00e+00	1269.00
IUUC-Pma-094580	Petromyzon marinus	87.74	0.00e+00	1170.00
IUUC-Pno-095085	Phaeosphaeria nodorum	34.71	4.00e-43	170.00
IUUC-Ppa-095594	Physcomitrella patens	35.60	4.00e-112	399.00
IUUC-Pfo-096994	Poecilia formosa	95.01	0.00e+00	1246.00
IUUC-Pab-097586	Pongo abelii	97.05	0.00e+00	1229.00
IUUC-Pop-099740	Populus trichocarpa	34.81	3.00e-102	366.00
IUUC-Pca-100458	Procavia capensis	97.60	3.00e-106	379.00
IUUC-Ppe-102060	Prunus persica	34.24	4.00e-107	382.00
IUUC-Pva-102698	Pteropus vampyrus	92.32	0.00e+00	1211.00
IUUC-Pgr-103649	Puccinia graminis	39.08	5.00e-48	186.00
IUUC-Ptt-103910	Puccinia triticina	43.50	2.00e-52	201.00
IUUC-Pte-104181	Pyrenophora teres	35.74	2.00e-47	184.00
IUUC-Pyt-104439	Pyrenophora triticirepentis	35.44	5.00e-47	183.00
IUUC-Rno-104978	Rattus norvegicus	95.76	0.00e+00	1222.00
IUUC-Sha-107079	Sarcophilus harrisii	95.94	0.00e+00	1178.00
IUUC-Sja-107716	Schizosaccharomyces japonicus	30.16	1.00e-58	221.00
IUUC-Spo-108325	Schizosaccharomyces pombe	30.06	1.00e-51	198.00
IUUC-Ssl-108542	Sclerotinia sclerotiorum	28.49	4.00e-46	179.00
IUUC-Smo-109427	Selaginella moellendorffii	35.23	3.00e-108	385.00
IUUC-Sit-110755	Setaria italica	36.21	5.00e-113	401.00
IUUC-Sly-111099	Solanum lycopersicum	35.01	6.00e-97	348.00
IUUC-Sar-113408	Sorex araneus	96.16	0.00e+00	748.00
IUUC-Sbi-113789	Sorghum bicolor	34.83	2.00e-109	389.00
IUUC-Sre-114998	Sporisorium reilianum	40.26	2.00e-52	201.00
IUUC-Ssc-115434	Sus scrofa	97.05	0.00e+00	1231.00
IUUC-Tgu-116517	Taeniopygia guttata	97.64	0.00e+00	1272.00
IUUC-Tru-118174	Takifugu rubripes	95.44	0.00e+00	1253.00
IUUC-Tsy-118935	Tarsius syrichta	96.75	0.00e+00	1256.00
IUUC-Tni-119744	Tetraodon nigroviridis	95.86	0.00e+00	1220.00
IUUC-Tca-121360	Theobroma cacao	34.24	7.00e-111	394.00
IUUC-Tre-122198	Trichoderma reesei	31.13	2.00e-42	167.00
IUUC-Tvi-122389	Trichoderma virens	31.66	4.00e-43	170.00
IUUC-Tae-125576	Triticum aestivum	34.69	2.00e-111	396.00
IUUC-Tur-126699	Triticum urartu	34.11	1.00e-108	387.00
IUUC-Tme-126932	Tuber melanosporum	30.50	5.00e-53	203.00
IUUC-Tbe-127267	Tupaia belangeri	82.12	0.00e+00	716.00
IUUC-Ttr-129153	Tursiops truncatus	96.45	0.00e+00	1260.00
IUUC-Uma-129604	Ustilago maydis	42.97	6.00e-50	193.00
IUUC-Vda-129925	Verticillium dahliae	34.97	3.00e-46	180.00
IUUC-Vpa-130553	Vicugna pacos	96.20	0.00e+00	961.00
IUUC-Vvi-130995	Vitis vinifera	33.98	7.00e-105	375.00
IUUC-Xtr-132346	Xenopus tropicalis	94.69	0.00e+00	1214.00
IUUC-Xma-134266	Xiphophorus maculatus	93.44	0.00e+00	655.00
IUUC-Yli-134451	Yarrowia lipolytica	26.74	2.00e-39	157.00
IUUC-Zma-135647	Zea mays	34.81	8.00e-111	394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence