iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117069

Ensembl Protein ID

ENSTGUP00000002199.1

UniProt Accession

H0YV78; H0YV78_TAEGU

Genbank Protein ID

ENSTGUP00000002199

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01050225

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000002111.1	ENSTGUT00000002219.1	ENSTGUP00000002199.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.70e-15	54.9	165	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL+ +kGd+++v     +++gW++g  +l+gk G fP+n+v++++
   Q: 165  VVKARFNFKQTNEDELSVNKGDIIYVT--RVEEGGWWEG--TLNGKTGWFPSNYVREIK 219
           68999*********************7..999*******..8**************997 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MNPEEQIVTW LISLGVLNSP KKIVDDPEGF LKTSLKDGTV LCKLINRLLP GSGEKYCLEP 60
KNEADCISNI QEFLKGCTLL KVEVFDPHDL YTGDQFSKVL STLTAVNKVT EDQLSKGPCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATCCAG AAGAACAGAT TGTAACGTGG CTTATTTCAC TAGGAGTCTT AAATTCCCCT 60
AAGAAAATAG TGGATGATCC AGAGGGGTTC CTGAAAACTT CTCTGAAAGA TGGAACTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	66.67	0.00e+00	1052.00
IUUC-Apl-003960	Anas platyrhynchos	93.55	0.00e+00	1405.00
IUUC-Aca-004988	Anolis carolinensis	79.33	0.00e+00	1173.00
IUUC-Aly-005591	Arabidopsis lyrata	39.39	2.00e-09	56.20
IUUC-Ame-011546	Astyanax mexicanus	65.47	0.00e+00	946.00
IUUC-Bta-013527	Bos taurus	74.48	0.00e+00	1112.00
IUUC-Cja-018935	Callithrix jacchus	75.00	0.00e+00	1115.00
IUUC-Cfa-021269	Canis familiaris	74.55	0.00e+00	1108.00
IUUC-Cpo-021620	Cavia porcellus	71.32	0.00e+00	1058.00
IUUC-Csa-023415	Chlorocebus sabaeus	74.87	0.00e+00	1115.00
IUUC-Dre-028580	Danio rerio	64.85	0.00e+00	974.00
IUUC-Dno-029201	Dasypus novemcinctus	70.29	0.00e+00	1085.00
IUUC-Dor-030868	Dipodomys ordii	59.92	0.00e+00	807.00
IUUC-Eca-033500	Equus caballus	74.74	0.00e+00	1106.00
IUUC-Eeu-035269	Erinaceus europaeus	65.90	1.00e-131	463.00
IUUC-Fca-035683	Felis catus	74.04	0.00e+00	1085.00
IUUC-Fal-037611	Ficedula albicollis	95.35	0.00e+00	1435.00
IUUC-Gmo-038980	Gadus morhua	62.82	0.00e+00	907.00
IUUC-Gga-040940	Gallus gallus	91.10	0.00e+00	1387.00
IUUC-Gac-042203	Gasterosteus aculeatus	62.55	0.00e+00	942.00
IUUC-Ggo-044755	Gorilla gorilla	75.00	0.00e+00	1115.00
IUUC-Hsa-046210	Homo sapiens	74.61	0.00e+00	1112.00
IUUC-Lch-049517	Latimeria chalumnae	73.83	0.00e+00	1071.00
IUUC-Loc-052393	Lepisosteus oculatus	65.69	0.00e+00	998.00
IUUC-Laf-054196	Loxodonta africana	74.84	0.00e+00	1095.00
IUUC-Mcc-055716	Macaca mulatta	74.87	0.00e+00	1115.00
IUUC-Meu-056285	Macropus eugenii	68.47	6.00e-180	624.00
IUUC-Mtr-058576	Medicago truncatula	43.42	3.00e-12	65.90
IUUC-Mga-060029	Meleagris gallopavo	91.48	0.00e+00	1402.00
IUUC-Mmr-060803	Microcebus murinus	74.87	0.00e+00	1109.00
IUUC-Mdo-062654	Monodelphis domestica	75.84	0.00e+00	1129.00
IUUC-Mmu-063479	Mus musculus	72.91	0.00e+00	1071.00
IUUC-Mpu-066065	Mustela putorius furo	74.23	0.00e+00	1083.00
IUUC-Mlu-068222	Myotis lucifugus	73.62	0.00e+00	1074.00
IUUC-Nle-069379	Nomascus leucogenys	75.13	0.00e+00	1116.00
IUUC-Opr-070687	Ochotona princeps	58.18	0.00e+00	646.00
IUUC-Ont-072240	Oreochromis niloticus	60.44	0.00e+00	935.00
IUUC-Oan-073067	Ornithorhynchus anatinus	79.69	0.00e+00	1193.00
IUUC-Ocu-074852	Oryctolagus cuniculus	73.45	0.00e+00	1082.00
IUUC-Oba-075543	Oryza barthii	34.29	2.40e+00	26.60
IUUC-Ogu-078135	Oryza glumaepatula	34.29	2.30e+00	26.60
IUUC-Ome-081704	Oryza meridionalis	34.29	3.30e+00	26.60
IUUC-Oni-082520	Oryza nivara	34.29	8.50e-01	27.30
IUUC-Oru-085261	Oryza rufipogon	34.29	2.20e+00	26.90
IUUC-Oga-089048	Otolemur garnettii	70.07	0.00e+00	961.00
IUUC-Oar-089339	Ovis aries	74.61	0.00e+00	1115.00
IUUC-Pan-092666	Papio anubis	73.26	0.00e+00	1071.00
IUUC-Psi-093116	Pelodiscus sinensis	85.53	0.00e+00	1307.00
IUUC-Pfo-097394	Poecilia formosa	63.72	0.00e+00	941.00
IUUC-Pab-098567	Pongo abelii	75.00	0.00e+00	1116.00
IUUC-Pca-100997	Procavia capensis	64.52	0.00e+00	891.00
IUUC-Pva-102500	Pteropus vampyrus	72.81	0.00e+00	1055.00
IUUC-Ptt-103822	Puccinia triticina	22.48	4.00e-08	53.50
IUUC-Rno-104974	Rattus norvegicus	72.79	0.00e+00	1046.00
IUUC-Sly-111123	Solanum lycopersicum	39.68	5.00e-10	58.20
IUUC-Stu-112434	Solanum tuberosum	39.68	7.00e-10	57.80
IUUC-Sar-113420	Sorex araneus	72.42	0.00e+00	1049.00
IUUC-Ssc-115679	Sus scrofa	74.86	0.00e+00	976.00
IUUC-Tru-118488	Takifugu rubripes	58.69	0.00e+00	838.00
IUUC-Tsy-119243	Tarsius syrichta	67.74	0.00e+00	755.00
IUUC-Tni-120584	Tetraodon nigroviridis	62.08	0.00e+00	907.00
IUUC-Tbe-127994	Tupaia belangeri	60.95	0.00e+00	881.00
IUUC-Ttr-128839	Tursiops truncatus	73.45	0.00e+00	1070.00
IUUC-Vpa-130144	Vicugna pacos	69.76	0.00e+00	976.00
IUUC-Xtr-132624	Xenopus tropicalis	71.39	0.00e+00	1090.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence