iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000017220.10	ENSDART00000124689.3	ENSDARP00000107347.2
ENSDARG00000017220.10	ENSDART00000041811.7	ENSDARP00000041810.6
ENSDARG00000017220.10	ENSDART00000128840.2	ENSDARP00000111152.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	3.90e-36	125.4	178	357

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t gDGnCLl+A+s +++g++d+d+ l++ l+  + +  ++++ k+++++++++++k           ++e++++ kl+++e    
   Q: 178  LPLATSGDGNCLLHAASLGMWGFHDRDLmLRKSLYALMDHGQEREALKRRWRWQQTMQNKesglvyteeewQKEWNELLKLASSEprih 266
           6889*********************************************************************************9988 PP
   S: 75   .ak.g...............eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYdaLv 136
            ++ g               ee+h+f+La++L+rpi+vv++++l++         ++ggi+lpl++p++k +++p+vL+Y+++H++aLv
   Q: 267  ySTnGssgaesqeepvyeslEEFHVFVLAHVLRRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPANKcHRSPLVLAYDQAHFSALV 355
           83334677999*****************************************************************************9 PP
   S: 137  al 138
           ++
   Q: 356  SM 357
           86 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MTLDMDAVLS DFVRSTGAEP GLARDLLEGK NWDLSAALSD FEQLRQVHAG SLSCSFVEES 60
EYPSIEKEMA RTGRPLLHRQ DEAVQAATEK RLSRGISHAS STIVSLARSH VSSTGGTNEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTTGACGT TGTTGTTGTG GGAGTAAGAA TGTACTTAGT CGTCAAGTCT TTATAAGACA 60
AAAAGCAAGA CGTTTCTTTG ATATTTACAT AACACAACAA TAGCACACAA CCCAAGAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

SMART

SM00259--ZnF_A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006955--P:immune response
GO:0007219--P:Notch signaling pathway
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018468	Caenorhabditis elegans	48.68	1.00e-83	303.00
IUUC-Dor-031121	Dipodomys ordii	71.20	4.00e-168	584.00
IUUC-Gmo-039373	Gadus morhua	87.94	0.00e+00	778.00
IUUC-Gac-041806	Gasterosteus aculeatus	89.25	0.00e+00	839.00
IUUC-Opr-070564	Ochotona princeps	75.63	0.00e+00	636.00
IUUC-Ont-071542	Oreochromis niloticus	91.19	0.00e+00	858.00
IUUC-Ola-086490	Oryzias latipes	87.12	0.00e+00	807.00
IUUC-Pfo-096563	Poecilia formosa	90.09	0.00e+00	832.00
IUUC-Tru-117911	Takifugu rubripes	87.47	0.00e+00	831.00
IUUC-Tbe-127283	Tupaia belangeri	81.65	2.00e-178	619.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence