iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090171

Ensembl Protein ID

ENSOARP00000003858.1

UniProt Accession

W5P0B0; W5P0B0_SHEEP

Genbank Protein ID

ENSOARP00000003858

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01033358

Gene Name

AMBRA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000003608.1	ENSOART00000003926.1	ENSOARP00000003858.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.50e-08	32.5	93	126

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           gH    +c+ f ++  +l++sG+ Dg +++WDl+
   Q: 93   GHRRTPWCVTFhPTisGLIASGCLDGEVRIWDLH 126
           6777779*****76779***************97 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MKVIPEKNAV RILWGRERGT RTFGAQRLLQ ELVEDKTRCM KWEGKRVELP DSPRSTFLLA 60
FSPDRTLLAS THVNHNIYIT EVKTGKCVHS LIGHRRTPWC VTFHPTISGL IASGCLDGEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGGTTA TTCCAGAGAA GAATGCTGTC CGGATTCTCT GGGGGCGAGA ACGGGGCACT 60
CGGACCTTTG GAGCTCAGCG ACTTCTGCAG GAGCTGGTTG AAGATAAAAC CCGGTGTATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0045335--C:phagocytic vesicle
GO:0006914--P:autophagy
GO:0008285--P:negative regulation of cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0021915--P:neural tube development
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:2000785--P:regulation of autophagosome assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001917	Ailuropoda melanoleuca	94.72	0.00e+00	1747.00
IUUC-Atr-002557	Amborella trichopoda	37.74	6.00e-30	126.00
IUUC-Apl-004186	Anas platyrhynchos	85.22	0.00e+00	1892.00
IUUC-Aca-004419	Anolis carolinensis	80.15	0.00e+00	1756.00
IUUC-Aly-006308	Arabidopsis lyrata	42.33	1.00e-27	117.00
IUUC-Ath-007656	Arabidopsis thaliana	36.45	4.00e-28	120.00
IUUC-Ame-011354	Astyanax mexicanus	59.21	0.00e+00	1294.00
IUUC-Bta-012455	Bos taurus	97.82	0.00e+00	2191.00
IUUC-Bdi-014580	Brachypodium distachyon	42.33	5.00e-30	126.00
IUUC-Bol-016094	Brassica oleracea	44.81	1.00e-28	121.00
IUUC-Bra-017308	Brassica rapa	45.45	1.00e-29	124.00
IUUC-Cja-019073	Callithrix jacchus	90.56	1.00e-153	536.00
IUUC-Cfa-020994	Canis familiaris	94.73	0.00e+00	1418.00
IUUC-Cpo-022101	Cavia porcellus	94.82	0.00e+00	2048.00
IUUC-Csa-023273	Chlorocebus sabaeus	95.32	0.00e+00	1457.00
IUUC-Cin-025567	Ciona intestinalis	52.20	3.00e-56	213.00
IUUC-Csv-026005	Ciona savignyi	51.74	3.00e-56	211.00
IUUC-Dre-028282	Danio rerio	59.13	0.00e+00	1288.00
IUUC-Dno-029948	Dasypus novemcinctus	94.98	0.00e+00	2052.00
IUUC-Dor-030568	Dipodomys ordii	92.86	0.00e+00	1193.00
IUUC-Ete-032864	Echinops telfairi	90.97	0.00e+00	1132.00
IUUC-Eca-034392	Equus caballus	95.32	0.00e+00	1461.00
IUUC-Eeu-034440	Erinaceus europaeus	85.00	0.00e+00	1198.00
IUUC-Fca-035359	Felis catus	94.16	0.00e+00	2056.00
IUUC-Fal-037483	Ficedula albicollis	85.09	0.00e+00	1913.00
IUUC-Gmo-039343	Gadus morhua	75.18	0.00e+00	773.00
IUUC-Gga-040787	Gallus gallus	81.23	0.00e+00	1221.00
IUUC-Gac-041321	Gasterosteus aculeatus	63.23	0.00e+00	1355.00
IUUC-Gma-044022	Glycine max	36.14	1.00e-28	122.00
IUUC-Ggo-044775	Gorilla gorilla	97.77	0.00e+00	927.00
IUUC-Hsa-045708	Homo sapiens	95.73	0.00e+00	2086.00
IUUC-Hvu-047536	Hordeum vulgare	41.57	2.00e-29	124.00
IUUC-Itr-048376	Ictidomys tridecemlineatus	93.64	0.00e+00	1199.00
IUUC-Lch-050255	Latimeria chalumnae	69.21	0.00e+00	1398.00
IUUC-Lpe-050684	Leersia perrieri	41.76	2.00e-30	127.00
IUUC-Loc-052881	Lepisosteus oculatus	67.45	0.00e+00	1501.00
IUUC-Laf-053342	Loxodonta africana	92.89	0.00e+00	788.00
IUUC-Mcc-055848	Macaca mulatta	93.47	0.00e+00	2055.00
IUUC-Meu-056320	Macropus eugenii	82.55	0.00e+00	1053.00
IUUC-Mtr-058685	Medicago truncatula	39.68	3.00e-29	123.00
IUUC-Mga-059401	Meleagris gallopavo	84.29	0.00e+00	1655.00
IUUC-Mmr-061037	Microcebus murinus	94.32	0.00e+00	2061.00
IUUC-Mdo-062484	Monodelphis domestica	73.82	0.00e+00	1634.00
IUUC-Mmu-064090	Mus musculus	94.73	0.00e+00	2043.00
IUUC-Mac-065675	Musa acuminata	35.17	1.00e-29	125.00
IUUC-Mpu-066165	Mustela putorius furo	95.08	0.00e+00	1426.00
IUUC-Mlu-068038	Myotis lucifugus	88.38	0.00e+00	2083.00
IUUC-Nle-069361	Nomascus leucogenys	95.01	0.00e+00	1897.00
IUUC-Opr-070360	Ochotona princeps	97.35	0.00e+00	769.00
IUUC-Ont-071277	Oreochromis niloticus	64.06	0.00e+00	1367.00
IUUC-Oan-073623	Ornithorhynchus anatinus	81.77	0.00e+00	1021.00
IUUC-Ocu-074600	Oryctolagus cuniculus	94.53	0.00e+00	1373.00
IUUC-Oba-075024	Oryza barthii	38.19	5.00e-32	133.00
IUUC-Obr-076172	Oryza brachyantha	38.69	3.00e-32	133.00
IUUC-Ogl-077411	Oryza glaberrima	38.19	6.00e-32	132.00
IUUC-Ogu-078025	Oryza glumaepatula	38.19	8.00e-32	132.00
IUUC-Oni-082463	Oryza nivara	38.19	5.00e-32	133.00
IUUC-Opu-084041	Oryza punctata	38.19	1.00e-31	131.00
IUUC-Oru-085075	Oryza rufipogon	38.19	2.00e-31	131.00
IUUC-Osa-085781	Oryza sativa	38.19	7.00e-32	132.00
IUUC-Ola-086729	Oryzias latipes	63.81	0.00e+00	1385.00
IUUC-Olu-087735	Ostreococcus lucimarinus	40.32	7.00e-24	105.00
IUUC-Oga-089113	Otolemur garnettii	94.14	0.00e+00	1993.00
IUUC-Ptr-090970	Pan troglodytes	95.73	0.00e+00	2086.00
IUUC-Pan-092778	Papio anubis	95.20	0.00e+00	1455.00
IUUC-Psi-093571	Pelodiscus sinensis	84.48	0.00e+00	1916.00
IUUC-Pma-094563	Petromyzon marinus	73.75	1.00e-105	375.00
IUUC-Ppa-095832	Physcomitrella patens	36.36	1.00e-29	125.00
IUUC-Pfo-097365	Poecilia formosa	61.10	0.00e+00	1272.00
IUUC-Pab-098647	Pongo abelii	93.75	0.00e+00	1201.00
IUUC-Pop-099742	Populus trichocarpa	42.33	2.00e-29	124.00
IUUC-Pca-101035	Procavia capensis	89.31	0.00e+00	1142.00
IUUC-Ppe-101783	Prunus persica	42.22	2.00e-29	124.00
IUUC-Pva-103187	Pteropus vampyrus	95.64	0.00e+00	894.00
IUUC-Rno-105701	Rattus norvegicus	94.40	0.00e+00	2021.00
IUUC-Sha-107612	Sarcophilus harrisii	84.23	0.00e+00	1927.00
IUUC-Smo-109107	Selaginella moellendorffii	39.66	7.00e-27	115.00
IUUC-Sit-110786	Setaria italica	38.12	2.00e-32	134.00
IUUC-Sly-110859	Solanum lycopersicum	37.14	7.00e-31	129.00
IUUC-Stu-112031	Solanum tuberosum	37.62	5.00e-31	129.00
IUUC-Sar-113242	Sorex araneus	93.70	0.00e+00	1052.00
IUUC-Ssc-116094	Sus scrofa	96.15	0.00e+00	2098.00
IUUC-Tru-118308	Takifugu rubripes	61.24	0.00e+00	1321.00
IUUC-Tsy-119552	Tarsius syrichta	90.69	0.00e+00	1181.00
IUUC-Tca-121616	Theobroma cacao	38.57	6.00e-31	129.00
IUUC-Tae-124768	Triticum aestivum	42.17	5.00e-30	125.00
IUUC-Tur-126480	Triticum urartu	42.17	2.00e-30	127.00
IUUC-Tbe-127902	Tupaia belangeri	91.85	0.00e+00	928.00
IUUC-Ttr-129278	Tursiops truncatus	91.67	0.00e+00	1158.00
IUUC-Vpa-130741	Vicugna pacos	92.98	0.00e+00	731.00
IUUC-Vvi-131437	Vitis vinifera	45.45	5.00e-29	123.00
IUUC-Xtr-132247	Xenopus tropicalis	65.31	0.00e+00	1318.00
IUUC-Xma-134277	Xiphophorus maculatus	62.56	0.00e+00	1385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence