iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000010037.4	ENSCAFT00000027485.4	ENSCAFP00000025561.3
ENSCAFG00000010037.4	ENSCAFT00000015967.3	ENSCAFP00000014769.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-35	118.4	184	221
UBD/Beta-Prp	4.70e-55	187.1	286	543

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 184  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 221
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s+
   Q: 286  QRYMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSI 374
           689*****************99999988777778888888755522888888**************99999****************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ 
   Q: 375  QFCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrvsgdlsleEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHN 463
           **************************99998999*********98877778889*********************************** PP
   S: 175  ltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ v+ + +         v + +fs+++++++++ s+g + i+
   Q: 464  LLG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGTKVKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 543
           **9.*********555555..99****************99997777665444555677778999999999999999998876 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAEPPPARRP VPLIESELYF LIARYLSAGP CRRAAQVLVQ ELEQYQLLPK RLDWEGNEHN 60
RSYEELVLSN KHVAPDHLLQ ICQRIGPMLD KEIPPSISRV TSLLGAGRQS LLRTAKDCRH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC CCCCGCCCGC CCGACGCCCG GTGCCCCTCA TCGAGTCGGG TAAGCCGCGC 60
CGCCCGCGCC CTCCCCGCGG CGCCCCCGGC CCGGCCCGGC CCGGCCCGGC CCCGCCGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	31.19	8.00e-64	239.00
IUUC-Aml-002332	Ailuropoda melanoleuca	90.93	0.00e+00	3526.00
IUUC-Atr-002600	Amborella trichopoda	29.89	3.00e-69	258.00
IUUC-Apl-004083	Anas platyrhynchos	61.81	0.00e+00	2135.00
IUUC-Aly-006517	Arabidopsis lyrata	30.73	1.00e-73	272.00
IUUC-Ath-006577	Arabidopsis thaliana	30.43	8.00e-73	269.00
IUUC-Ame-010718	Astyanax mexicanus	71.08	0.00e+00	1170.00
IUUC-Bta-013217	Bos taurus	89.97	0.00e+00	3757.00
IUUC-Bol-015737	Brassica oleracea	30.17	3.00e-74	274.00
IUUC-Bra-017961	Brassica rapa	30.13	2.00e-73	271.00
IUUC-Cja-019966	Callithrix jacchus	87.34	0.00e+00	3619.00
IUUC-Cpo-021934	Cavia porcellus	91.95	0.00e+00	2741.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	34.15	8.00e-35	142.00
IUUC-Csa-023352	Chlorocebus sabaeus	87.59	0.00e+00	3390.00
IUUC-Cho-024690	Choloepus hoffmanni	79.28	0.00e+00	1343.00
IUUC-Dre-028205	Danio rerio	68.56	0.00e+00	1147.00
IUUC-Dno-028938	Dasypus novemcinctus	85.02	0.00e+00	3564.00
IUUC-Eca-034349	Equus caballus	90.87	0.00e+00	3581.00
IUUC-Fca-035485	Felis catus	92.82	0.00e+00	3210.00
IUUC-Gma-044324	Glycine max	30.61	2.00e-70	261.00
IUUC-Ggo-045500	Gorilla gorilla	88.23	0.00e+00	3652.00
IUUC-Hsa-046350	Homo sapiens	88.51	0.00e+00	3672.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	95.78	0.00e+00	1131.00
IUUC-Lch-049662	Latimeria chalumnae	66.71	0.00e+00	2095.00
IUUC-Lpe-051619	Leersia perrieri	31.65	4.00e-71	264.00
IUUC-Laf-053848	Loxodonta africana	87.46	0.00e+00	3571.00
IUUC-Mcc-054638	Macaca mulatta	88.41	0.00e+00	3657.00
IUUC-Meu-056739	Macropus eugenii	79.91	0.00e+00	1115.00
IUUC-Mtr-058094	Medicago truncatula	30.67	2.00e-72	268.00
IUUC-Mga-060165	Meleagris gallopavo	77.69	0.00e+00	2271.00
IUUC-Mmr-061227	Microcebus murinus	89.03	0.00e+00	3689.00
IUUC-Mdo-062074	Monodelphis domestica	71.77	0.00e+00	2803.00
IUUC-Mmu-064075	Mus musculus	82.25	0.00e+00	2961.00
IUUC-Mac-065343	Musa acuminata	30.85	6.00e-77	283.00
IUUC-Mpu-066643	Mustela putorius furo	96.37	0.00e+00	3158.00
IUUC-Mlu-067735	Myotis lucifugus	87.61	0.00e+00	3534.00
IUUC-Nle-069402	Nomascus leucogenys	91.86	0.00e+00	3004.00
IUUC-Oan-072954	Ornithorhynchus anatinus	70.23	0.00e+00	2846.00
IUUC-Ocu-074456	Oryctolagus cuniculus	85.31	0.00e+00	3563.00
IUUC-Oba-075709	Oryza barthii	30.62	1.00e-61	232.00
IUUC-Obr-076619	Oryza brachyantha	31.34	2.00e-71	265.00
IUUC-Opu-083233	Oryza punctata	30.90	4.00e-66	247.00
IUUC-Oru-085195	Oryza rufipogon	30.62	1.00e-61	232.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.06	1.00e-55	211.00
IUUC-Oga-087938	Otolemur garnettii	81.66	0.00e+00	3142.00
IUUC-Oar-090214	Ovis aries	89.23	0.00e+00	3607.00
IUUC-Ptr-091213	Pan troglodytes	88.51	0.00e+00	3633.00
IUUC-Pan-092444	Papio anubis	87.62	0.00e+00	3640.00
IUUC-Pma-094427	Petromyzon marinus	66.98	7.00e-132	463.00
IUUC-Ppa-095793	Physcomitrella patens	29.84	2.00e-74	275.00
IUUC-Pfo-097318	Poecilia formosa	61.82	0.00e+00	1760.00
IUUC-Pab-097573	Pongo abelii	87.52	0.00e+00	3536.00
IUUC-Pop-099672	Populus trichocarpa	31.18	4.00e-73	270.00
IUUC-Pca-100759	Procavia capensis	70.59	0.00e+00	1153.00
IUUC-Ppe-101849	Prunus persica	30.81	1.00e-75	278.00
IUUC-Pva-102782	Pteropus vampyrus	89.16	0.00e+00	3635.00
IUUC-Rno-105687	Rattus norvegicus	77.67	0.00e+00	3210.00
IUUC-Sha-106680	Sarcophilus harrisii	88.85	0.00e+00	1471.00
IUUC-Sly-111348	Solanum lycopersicum	30.56	3.00e-76	281.00
IUUC-Sar-113519	Sorex araneus	82.05	0.00e+00	1788.00
IUUC-Sbi-114195	Sorghum bicolor	29.39	3.00e-59	223.00
IUUC-Tsy-118921	Tarsius syrichta	89.24	0.00e+00	1977.00
IUUC-Tca-121615	Theobroma cacao	30.19	3.00e-68	254.00
IUUC-Tae-125478	Triticum aestivum	30.68	3.00e-73	270.00
IUUC-Tur-126809	Triticum urartu	30.67	1.00e-70	262.00
IUUC-Tbe-127663	Tupaia belangeri	77.01	0.00e+00	1299.00
IUUC-Ttr-128561	Tursiops truncatus	87.40	0.00e+00	3509.00
IUUC-Vpa-130444	Vicugna pacos	86.66	0.00e+00	3390.00
IUUC-Vvi-131362	Vitis vinifera	31.17	1.00e-74	275.00
IUUC-Xma-133633	Xiphophorus maculatus	68.82	0.00e+00	1117.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence