iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073880

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02002624

Gene Name

USP24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000015591.3	ENSOCUT00000015635.3	ENSOCUP00000013429.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.90e-79	265.5	1687	2039

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgy 87
           +Gl+N g+tCYmN+v Q+L++ p l e ll+     ++++  ++p+ ++  ++q+lf +l++sk +++ p++++k++k++++e+   
   Q: 1687 VGLRNGGATCYMNAVFQQLYMQPGLPESLLS-----VDDD-TDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVR 1767
           6******************************.....5444.468999**************************************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           eqqDa Ef++ l+dq++e+l                          kk+  +++ +++Fqg +++q +c++c ++++ree f+ l+l
   Q: 1768 EQQDAYEFFTSLIDQMDEYL--------------------------KKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNL 1828
           ********************..........................78999************************************ PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
            v + +     sl+ +L++f++ e leg+n+yycekck+k+ ++k++ +k+lP vL++hL+Rf f+ e ++++k ++++ fp +L++
   Q: 1829 GVTSCQ-----SLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNM 1910
           ******.....9*************************************************************************** PP
   S: 262  spfcts.........................peekqkekkkYeLiavvvHsGslssGHYvayvkn....ekgkWllfdDskVtevk. 318
           +p+++s                         p +k++ +++YeL++v+vHsG+++ GHY++++k+     kgkW++f+D+ ++e + 
   Q: 1911 EPYTVSgmarldsssevgengrsvdqggggsPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDrrgcGKGKWYKFNDTVIEEFDl 1997
           ******88888777777776666666666665555555***************************55555666************84 PP
   S: 319  eeevleetg.......................staYvlfYkr 337
            +e le +                        ++aY+lfY+r
   Q: 1998 NDETLEYECfggeyrpkvydqtnpytdvrrryWNAYMLFYQR 2039
           4666664449******************************98 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MESEEEQHMT TLLCMGFSDP ATIRKALRLA KNDINEAVAL LTNERPGLDY GGYEPMDSGG 60
GPSPGGGPRG DGGGDGGGGG PSRGGSTGGG GGFDPPPAYH EVVDAEKNDE NGNCSGEGIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAATCGG AGGAGGAGCA GCACATGACC ACGTTGCTGT GCATGGGCTT CTCGGACCCC 60
GCCACCATCC GCAAGGCCCT GCGCCTGGCC AAGAACGACA TCAACGAGGC CGTGGCGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR033382--USP24
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002266	Ailuropoda melanoleuca	97.98	0.00e+00	4786.00
IUUC-Apl-003203	Anas platyrhynchos	74.43	0.00e+00	3466.00
IUUC-Aca-004396	Anolis carolinensis	89.33	0.00e+00	4467.00
IUUC-Ame-011886	Astyanax mexicanus	84.24	0.00e+00	1759.00
IUUC-Bta-013381	Bos taurus	97.02	0.00e+00	4850.00
IUUC-Cel-018352	Caenorhabditis elegans	29.80	7.00e-62	234.00
IUUC-Cja-018955	Callithrix jacchus	97.46	0.00e+00	4372.00
IUUC-Cfa-020720	Canis familiaris	97.78	0.00e+00	4770.00
IUUC-Cpo-022430	Cavia porcellus	94.89	0.00e+00	3391.00
IUUC-Csa-024180	Chlorocebus sabaeus	97.96	0.00e+00	4593.00
IUUC-Cho-025074	Choloepus hoffmanni	92.34	0.00e+00	1828.00
IUUC-Dre-027696	Danio rerio	80.17	0.00e+00	4053.00
IUUC-Dno-029307	Dasypus novemcinctus	95.09	0.00e+00	4721.00
IUUC-Dor-030889	Dipodomys ordii	94.31	0.00e+00	4566.00
IUUC-Ete-032294	Echinops telfairi	91.57	0.00e+00	2292.00
IUUC-Eca-033823	Equus caballus	92.24	0.00e+00	4467.00
IUUC-Eeu-035178	Erinaceus europaeus	87.55	0.00e+00	2091.00
IUUC-Fca-035444	Felis catus	97.81	0.00e+00	4713.00
IUUC-Fal-037555	Ficedula albicollis	92.08	0.00e+00	4486.00
IUUC-Gmo-038587	Gadus morhua	79.13	0.00e+00	2452.00
IUUC-Gga-041231	Gallus gallus	91.71	0.00e+00	4600.00
IUUC-Gac-041584	Gasterosteus aculeatus	79.13	0.00e+00	2420.00
IUUC-Ggo-044502	Gorilla gorilla	97.10	0.00e+00	4832.00
IUUC-Hsa-045851	Homo sapiens	97.18	0.00e+00	4848.00
IUUC-Itr-048746	Ictidomys tridecemlineatus	97.47	0.00e+00	1562.00
IUUC-Lch-049999	Latimeria chalumnae	79.00	0.00e+00	3889.00
IUUC-Loc-051767	Lepisosteus oculatus	81.93	0.00e+00	4079.00
IUUC-Laf-054139	Loxodonta africana	96.91	0.00e+00	4837.00
IUUC-Mcc-055217	Macaca mulatta	97.29	0.00e+00	4843.00
IUUC-Meu-056659	Macropus eugenii	81.61	0.00e+00	2247.00
IUUC-Mga-059267	Meleagris gallopavo	92.36	0.00e+00	4526.00
IUUC-Mmr-060971	Microcebus murinus	96.05	0.00e+00	4792.00
IUUC-Mdo-061925	Monodelphis domestica	93.49	0.00e+00	4597.00
IUUC-Mmu-064019	Mus musculus	96.37	0.00e+00	4899.00
IUUC-Mpu-066652	Mustela putorius furo	97.17	0.00e+00	4888.00
IUUC-Mlu-067518	Myotis lucifugus	97.57	0.00e+00	4714.00
IUUC-Nle-069763	Nomascus leucogenys	97.77	0.00e+00	4717.00
IUUC-Opr-071031	Ochotona princeps	91.56	0.00e+00	4399.00
IUUC-Ont-072136	Oreochromis niloticus	77.90	0.00e+00	3962.00
IUUC-Oan-072908	Ornithorhynchus anatinus	82.84	0.00e+00	934.00
IUUC-Ola-086544	Oryzias latipes	76.74	0.00e+00	3809.00
IUUC-Oga-088695	Otolemur garnettii	97.10	0.00e+00	4894.00
IUUC-Oar-089401	Ovis aries	97.21	0.00e+00	4699.00
IUUC-Ptr-091657	Pan troglodytes	98.05	0.00e+00	4746.00
IUUC-Pan-092394	Papio anubis	97.33	0.00e+00	4845.00
IUUC-Psi-093813	Pelodiscus sinensis	92.45	0.00e+00	4496.00
IUUC-Pma-094698	Petromyzon marinus	53.73	2.00e-139	489.00
IUUC-Pfo-096811	Poecilia formosa	78.60	0.00e+00	3950.00
IUUC-Pab-097814	Pongo abelii	97.21	0.00e+00	4843.00
IUUC-Pca-101135	Procavia capensis	93.50	0.00e+00	2227.00
IUUC-Pva-102334	Pteropus vampyrus	92.58	0.00e+00	4596.00
IUUC-Rno-105040	Rattus norvegicus	96.10	0.00e+00	4854.00
IUUC-Sha-106658	Sarcophilus harrisii	93.84	0.00e+00	4610.00
IUUC-Sar-113153	Sorex araneus	86.03	0.00e+00	2722.00
IUUC-Ssc-115641	Sus scrofa	95.98	0.00e+00	4556.00
IUUC-Tgu-117467	Taeniopygia guttata	92.53	0.00e+00	3272.00
IUUC-Tru-118074	Takifugu rubripes	71.88	0.00e+00	3415.00
IUUC-Tsy-119165	Tarsius syrichta	93.31	0.00e+00	4462.00
IUUC-Tni-119923	Tetraodon nigroviridis	68.14	0.00e+00	3182.00
IUUC-Tbe-127910	Tupaia belangeri	89.86	0.00e+00	1793.00
IUUC-Ttr-128218	Tursiops truncatus	96.18	0.00e+00	4692.00
IUUC-Vpa-130090	Vicugna pacos	96.89	0.00e+00	1700.00
IUUC-Xtr-131911	Xenopus tropicalis	86.38	0.00e+00	1710.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence