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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046725
Ensembl Protein ID ENSP00000344562.5
UniProt Accession Q6QEF8; B3KU26; Q71MF3; Q8WYH7; Q96K02; CORO6_HUMAN
Genbank Protein ID AAG22467.1; AAQ04659.1; AAQ04660.1; AAS48630.1; BAB55360.1; BAG53288.1; AAH64514.1
Protein Name Coronin-6; Coronin-like protein E
Genbank Nucleotide ID AF193039; AF447884; AF447885; AY545070; AK027777; AK096431; AC104564
Gene Name CORO6; PP1009; PP1782; PP1881
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000167549.18 ENST00000345068.9 ENSP00000344562.5
ENSG00000167549.18 ENST00000580212.5 ENSP00000463723.1
ENSG00000167549.18 ENST00000480954.6 ENSP00000464621.1
ENSG00000167549.18 ENST00000584969.5 ENSP00000462627.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICHPM
DNA & RNA Element
UTRdbcircBaseCircNetmiRTarBase
microRNATRANSFACRepTarmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
InWeb_IM
Disease-associated Variation
ClinVar
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMHPRD
BioGRID
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.70e-16 60.7 79 110
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWD 29
           gHt++v ++++   +d+ ++s+sdD ti+vW 
   Q: 79   GHTAPVLDIDWcphNDNVIASASDDTTIMVWQ 110
           8***********9877***************7 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MSRRVVRQSK FRHVFGQAAK ADQAYEDIRV SKVTWDSSFC AVNPKFLAII VEAGGGGAFI 60
VLPLAKTGRV DKNYPLVTGH TAPVLDIDWC PHNDNVIASA SDDTTIMVWQ IPDYTPMRNI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046725|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTTAGGTTGA TGGCAGCGGC AGCTGGGGCT GCAGCGGCGC CGGGCTCTAG AGAGCCGCAG 60
GATCGGCCAG AGTGCGGAGC TGGACACCCG GGTCCCAGAT ACTACAGACA CCCGGAGAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046725|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR027337--CORO6
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12894--ANAPC4_WD40
PF08953--DUF1899
PF00400--WD40
SMART

SM01166--DUF1899
SM00320--WD40
Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
KEGG hsa:84940
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001462 Ailuropoda melanoleuca 95.80 0.00e+00 938.00
IUUC-Aca-005215 Anolis carolinensis 81.14 0.00e+00 804.00
IUUC-Ago-007901 Ashbya gossypii 40.63 2.00e-90 326.00
IUUC-Ame-011142 Astyanax mexicanus 74.73 0.00e+00 764.00
IUUC-Bgr-011990 Blumeria graminis 39.96 1.00e-97 350.00
IUUC-Bta-013160 Bos taurus 89.19 0.00e+00 855.00
IUUC-Cel-018669 Caenorhabditis elegans 53.42 5.00e-116 411.00
IUUC-Cja-019934 Callithrix jacchus 98.09 0.00e+00 961.00
IUUC-Cfa-020414 Canis familiaris 98.09 0.00e+00 965.00
IUUC-Cpo-022256 Cavia porcellus 94.49 0.00e+00 932.00
IUUC-Csa-023319 Chlorocebus sabaeus 98.94 0.00e+00 939.00
IUUC-Dre-028652 Danio rerio 76.71 0.00e+00 732.00
IUUC-Dor-030506 Dipodomys ordii 97.46 0.00e+00 958.00
IUUC-Eca-033550 Equus caballus 95.97 0.00e+00 945.00
IUUC-Eeu-035286 Erinaceus europaeus 97.99 8.00e-176 608.00
IUUC-Fca-035787 Felis catus 95.34 0.00e+00 942.00
IUUC-Fal-036912 Ficedula albicollis 83.69 0.00e+00 843.00
IUUC-Gmo-038645 Gadus morhua 72.40 0.00e+00 738.00
IUUC-Gga-040968 Gallus gallus 82.42 0.00e+00 822.00
IUUC-Gac-042489 Gasterosteus aculeatus 71.19 0.00e+00 721.00
IUUC-Ggo-044731 Gorilla gorilla 99.36 0.00e+00 968.00
IUUC-Itr-048296 Ictidomys tridecemlineatus 98.52 0.00e+00 942.00
IUUC-Kpa-049089 Komagataella pastoris 44.74 2.00e-96 347.00
IUUC-Lch-049723 Latimeria chalumnae 71.52 0.00e+00 706.00
IUUC-Loc-052779 Lepisosteus oculatus 70.51 0.00e+00 716.00
IUUC-Laf-054086 Loxodonta africana 97.67 0.00e+00 964.00
IUUC-Mcc-055571 Macaca mulatta 95.76 0.00e+00 909.00
IUUC-Mga-059353 Meleagris gallopavo 79.96 0.00e+00 805.00
IUUC-Mvi-060569 Microbotryum violaceum 39.40 8.00e-88 318.00
IUUC-Mmr-060830 Microcebus murinus 98.52 0.00e+00 970.00
IUUC-Mdo-062184 Monodelphis domestica 91.56 0.00e+00 879.00
IUUC-Mmu-064073 Mus musculus 93.43 0.00e+00 889.00
IUUC-Mpu-066824 Mustela putorius furo 98.52 0.00e+00 968.00
IUUC-Mlu-066994 Myotis lucifugus 94.92 0.00e+00 927.00
IUUC-Nle-069218 Nomascus leucogenys 100.00 0.00e+00 981.00
IUUC-Opr-071137 Ochotona princeps 98.31 0.00e+00 966.00
IUUC-Ont-071691 Oreochromis niloticus 73.25 0.00e+00 729.00
IUUC-Oan-073671 Ornithorhynchus anatinus 84.53 0.00e+00 793.00
IUUC-Ocu-074167 Oryctolagus cuniculus 96.82 0.00e+00 956.00
IUUC-Ola-086676 Oryzias latipes 71.05 0.00e+00 739.00
IUUC-Oga-088077 Otolemur garnettii 98.94 0.00e+00 969.00
IUUC-Oar-089260 Ovis aries 97.67 0.00e+00 957.00
IUUC-Ptr-090488 Pan troglodytes 99.36 0.00e+00 968.00
IUUC-Pan-091682 Papio anubis 99.15 0.00e+00 945.00
IUUC-Pfo-096186 Poecilia formosa 73.04 0.00e+00 725.00
IUUC-Pab-098768 Pongo abelii 91.10 0.00e+00 866.00
IUUC-Pca-100926 Procavia capensis 93.32 0.00e+00 809.00
IUUC-Pva-102483 Pteropus vampyrus 93.64 0.00e+00 894.00
IUUC-Rno-104937 Rattus norvegicus 96.40 0.00e+00 924.00
IUUC-Sce-106378 Saccharomyces cerevisiae 41.57 4.00e-93 335.00
IUUC-Sha-107180 Sarcophilus harrisii 83.89 0.00e+00 681.00
IUUC-Spo-108364 Schizosaccharomyces pombe 43.67 7.00e-98 351.00
IUUC-Ssc-116384 Sus scrofa 83.26 0.00e+00 776.00
IUUC-Tgu-117038 Taeniopygia guttata 81.54 0.00e+00 745.00
IUUC-Tru-118281 Takifugu rubripes 70.89 0.00e+00 721.00
IUUC-Tni-120360 Tetraodon nigroviridis 71.82 0.00e+00 720.00
IUUC-Tbe-127703 Tupaia belangeri 93.31 0.00e+00 676.00
IUUC-Ttr-128355 Tursiops truncatus 92.80 0.00e+00 890.00
IUUC-Xtr-132642 Xenopus tropicalis 70.40 0.00e+00 714.00
IUUC-Xma-133704 Xiphophorus maculatus 73.04 0.00e+00 723.00
Created Date 25-Jun-2017

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