iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026960

Ensembl Protein ID

AAW40755

UniProt Accession

Q5KPX3; Q5KPX3_CRYNJ

Genbank Protein ID

AAW40755.1

Protein Name

Ubiquitin activating enzyme, putative

Genbank Nucleotide ID

AE017341

Gene Name

CNA01230

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNA01230	AAW40755	AAW40755

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.70e-191	635.2	414	895

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnve..ahe 94
           YD+Qi+++G   qek+++++ +lvG g++GcE+lKn  ++G+     g i+v+D dt+e+snlnrqFLfra+dvgk KAe+aa+a++++np+ +++  ah 
   Q: 414  YDGQIAVFGKAFQEKISNTREFLVGSGAIGCEMLKNWSMMGLatgpnGIIHVTDLDTIEKSNLNRQFLFRAKDVGKFKAESAAAAVADMNPNLKGKiiAHD 514
           *********************************************************************************************86533899 PP
   S: 95   esiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.. 190
           +++ +++e+++   Ff ++d+V +aldn++ar +++r+c+ +++pl+esgtlG++ +++v++++lte+ys+s+dpp+k+iP ct+k++pna+ehti+wa  
   Q: 515  DRVGPETENVYgdeFFANLDGVTNALDNVSARQYMDRRCVFYCKPLLESGTLGTKANTQVVVPHLTESYSSSQDPPEKSIPSCTVKNFPNAIEHTIQWAre 615
           ***************************************************************************************************** PP
   S: 191  ..........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv....... 274
                       +n +l++ ++ e++l+   s +  e ++++++ l++e++ +fee+i +a+ + ++ + n+ikqll ++++d+v+ +++pfw+       
   Q: 616  afdsffvnppTTVNLYLSQPDFVETTLKS--SGQHHEHLKQIEKYLVKERPMSFEECIMWARLQYENNYVNEIKQLLFNLPKDQVNANGTPFWSgpkrapt 714
           *********999999**999999999995..688899999999********************************************************** PP
   S: 275  ...................................sfcsnaealqvp....ekvekdeevvkasap.........lylllralerfekkkgrkpgelsfek 327
                                               f +++e+ +vp    ++++k +++  ++ +         +++ + +l   ++  g   + ++fek
   Q: 715  alafniddpldmeyliaaanlhafnyglkgerdpaLFRKVVESMNVPeftpKSGVKIQINENEPVEnngnddeddIEAIVSSLPPPASLAGFRLQPVDFEK 815
           ***********************************7777777777553333333333333333333555555666************************** PP
   S: 328  ddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           ddds  ++d++taa+nlra ++gi   +d++++k iag+iipaiatt+a   Gl+++E++K+++g  k e +kn f+++a+
   Q: 816  DDDSnhHIDFITAASNLRARNYGITL-ADRHKTKLIAGKIIPAIATTTALAVGLVCLELYKLIDGknKLEDYKNGFVNLAL 895
           **************************.**************************************999999*****99875 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MAAPMQVDEA VPGDSIDEGL YSRQLYVLGH EAMKKMATSN VLIVGMKGLG VEIAKNVALA 60
GVKTVTIYDP SAVEIADLGT QFFLREEDIG RPRAEVTAPR LAELNSYVPI KILPGAGEIT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTATTCTC TTGCATTCCA TCTCAAATAC ATTCATATAA ATTCCTCTTC TTTCTTACAC 60
CGTGTACTAG ATACGACCTT TGGAGGAAGA ATCCCTATTG TCACTTTGAA CGAAAACAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004839--F:ubiquitin activating enzyme activity

KEGG

cne:CNA01230

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	44.71	0.00e+00	819.00
IUUC-Aml-001311	Ailuropoda melanoleuca	55.83	0.00e+00	1126.00
IUUC-Atr-002684	Amborella trichopoda	44.95	0.00e+00	880.00
IUUC-Apl-004158	Anas platyrhynchos	42.37	0.00e+00	692.00
IUUC-Aca-004620	Anolis carolinensis	56.47	0.00e+00	1128.00
IUUC-Aly-005418	Arabidopsis lyrata	45.44	0.00e+00	905.00
IUUC-Ath-006992	Arabidopsis thaliana	45.14	0.00e+00	888.00
IUUC-Ago-007873	Ashbya gossypii	56.55	0.00e+00	1100.00
IUUC-Acl-008181	Aspergillus clavatus	60.98	0.00e+00	1229.00
IUUC-Afl-008455	Aspergillus flavus	61.31	0.00e+00	1195.00
IUUC-Afu-009065	Aspergillus fumigatus	61.76	0.00e+00	1269.00
IUUC-Ani-009371	Aspergillus nidulans	61.03	0.00e+00	1216.00
IUUC-Ang-009737	Aspergillus niger	61.08	0.00e+00	1230.00
IUUC-Aor-010007	Aspergillus oryzae	61.31	0.00e+00	1195.00
IUUC-Ate-010466	Aspergillus terreus	60.46	0.00e+00	1254.00
IUUC-Ame-010933	Astyanax mexicanus	57.16	0.00e+00	1086.00
IUUC-Bgr-012281	Blumeria graminis	57.71	0.00e+00	1189.00
IUUC-Bta-012767	Bos taurus	55.85	0.00e+00	1135.00
IUUC-Bci-013721	Botrytis cinerea	59.67	0.00e+00	1174.00
IUUC-Bdi-014843	Brachypodium distachyon	44.44	0.00e+00	844.00
IUUC-Bol-015665	Brassica oleracea	46.71	0.00e+00	900.00
IUUC-Bra-017707	Brassica rapa	46.06	0.00e+00	909.00
IUUC-Cel-018260	Caenorhabditis elegans	46.86	0.00e+00	834.00
IUUC-Cja-019152	Callithrix jacchus	55.75	0.00e+00	1129.00
IUUC-Cfa-020622	Canis familiaris	54.96	0.00e+00	1078.00
IUUC-Cpo-022526	Cavia porcellus	56.13	0.00e+00	1128.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	44.19	0.00e+00	782.00
IUUC-Csa-023780	Chlorocebus sabaeus	55.75	0.00e+00	1128.00
IUUC-Cho-024682	Choloepus hoffmanni	40.98	4.00e-97	347.00
IUUC-Cin-025790	Ciona intestinalis	54.59	0.00e+00	1110.00
IUUC-Csv-026084	Ciona savignyi	54.00	0.00e+00	1088.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	59.77	0.00e+00	1243.00
IUUC-Cme-027290	Cyanidioschyzon merolae	43.35	0.00e+00	805.00
IUUC-Dre-028149	Danio rerio	56.56	0.00e+00	1107.00
IUUC-Dno-028884	Dasypus novemcinctus	56.35	0.00e+00	1142.00
IUUC-Dor-030229	Dipodomys ordii	53.77	0.00e+00	1071.00
IUUC-Dse-031524	Dothistroma septosporum	58.54	0.00e+00	1168.00
IUUC-Dme-032045	Drosophila melanogaster	54.08	0.00e+00	1072.00
IUUC-Ete-033124	Echinops telfairi	41.86	1.00e-144	505.00
IUUC-Eca-033330	Equus caballus	56.15	0.00e+00	1138.00
IUUC-Eeu-035323	Erinaceus europaeus	43.55	1.00e-153	535.00
IUUC-Fca-036255	Felis catus	56.13	0.00e+00	1133.00
IUUC-Fal-036848	Ficedula albicollis	42.58	0.00e+00	701.00
IUUC-Fox-038007	Fusarium oxysporum	58.69	0.00e+00	626.00
IUUC-Fso-038339	Fusarium solani	60.12	0.00e+00	1185.00
IUUC-Gmo-039338	Gadus morhua	55.80	0.00e+00	1090.00
IUUC-Ggr-039823	Gaeumannomyces graminis	60.37	0.00e+00	1256.00
IUUC-Gga-040747	Gallus gallus	42.16	0.00e+00	692.00
IUUC-Gac-041773	Gasterosteus aculeatus	54.69	0.00e+00	1068.00
IUUC-Gma-043198	Glycine max	45.32	0.00e+00	874.00
IUUC-Ggo-045336	Gorilla gorilla	55.93	0.00e+00	1125.00
IUUC-Hsa-045982	Homo sapiens	55.93	0.00e+00	1125.00
IUUC-Hvu-047418	Hordeum vulgare	45.20	0.00e+00	859.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	56.05	0.00e+00	1136.00
IUUC-Kpa-049112	Komagataella pastoris	55.19	0.00e+00	1069.00
IUUC-Lch-050371	Latimeria chalumnae	57.45	0.00e+00	1133.00
IUUC-Lpe-051299	Leersia perrieri	44.16	0.00e+00	872.00
IUUC-Loc-052936	Lepisosteus oculatus	57.16	0.00e+00	1124.00
IUUC-Lma-053315	Leptosphaeria maculans	60.22	0.00e+00	1234.00
IUUC-Laf-053948	Loxodonta africana	55.36	0.00e+00	1106.00
IUUC-Mcc-055843	Macaca mulatta	56.05	0.00e+00	1136.00
IUUC-Meu-056258	Macropus eugenii	56.10	0.00e+00	1129.00
IUUC-Mor-057269	Magnaporthe oryzae	60.70	0.00e+00	1238.00
IUUC-Mpo-057435	Magnaporthe poae	59.94	0.00e+00	1224.00
IUUC-Mtr-058572	Medicago truncatula	45.88	0.00e+00	874.00
IUUC-Mla-059176	Melampsora laricipopulina	64.91	0.00e+00	1313.00
IUUC-Mga-059721	Meleagris gallopavo	43.18	0.00e+00	676.00
IUUC-Mvi-060437	Microbotryum violaceum	61.64	0.00e+00	1274.00
IUUC-Mmr-061405	Microcebus murinus	55.06	0.00e+00	1100.00
IUUC-Mdo-062032	Monodelphis domestica	55.01	0.00e+00	1093.00
IUUC-Mmu-063280	Mus musculus	55.63	0.00e+00	1129.00
IUUC-Mac-065505	Musa acuminata	45.54	0.00e+00	887.00
IUUC-Mpu-066409	Mustela putorius furo	56.15	0.00e+00	1142.00
IUUC-Mlu-067217	Myotis lucifugus	55.36	0.00e+00	1117.00
IUUC-Nfi-068407	Neosartorya fischeri	61.17	0.00e+00	1236.00
IUUC-Ncr-068698	Neurospora crassa	60.78	0.00e+00	1239.00
IUUC-Nle-070072	Nomascus leucogenys	53.25	0.00e+00	1041.00
IUUC-Opr-070715	Ochotona princeps	38.27	0.00e+00	634.00
IUUC-Ont-071671	Oreochromis niloticus	57.45	0.00e+00	1113.00
IUUC-Oan-073268	Ornithorhynchus anatinus	41.68	0.00e+00	646.00
IUUC-Ocu-074544	Oryctolagus cuniculus	56.35	0.00e+00	1143.00
IUUC-Oba-075120	Oryza barthii	44.63	0.00e+00	859.00
IUUC-Obr-076557	Oryza brachyantha	44.71	0.00e+00	847.00
IUUC-Ogl-077887	Oryza glaberrima	44.53	0.00e+00	859.00
IUUC-Ogu-078305	Oryza glumaepatula	43.67	0.00e+00	862.00
IUUC-Oin-079370	Oryza indica	43.74	0.00e+00	844.00
IUUC-Olo-081089	Oryza longistaminata	43.87	0.00e+00	866.00
IUUC-Ome-081942	Oryza meridionalis	44.48	0.00e+00	862.00
IUUC-Oni-082365	Oryza nivara	44.73	0.00e+00	864.00
IUUC-Opu-083977	Oryza punctata	44.83	0.00e+00	868.00
IUUC-Oru-084469	Oryza rufipogon	43.77	0.00e+00	864.00
IUUC-Osa-085949	Oryza sativa	44.83	0.00e+00	871.00
IUUC-Ola-087002	Oryzias latipes	56.86	0.00e+00	1110.00
IUUC-Olu-087687	Ostreococcus lucimarinus	43.43	0.00e+00	773.00
IUUC-Oga-088594	Otolemur garnettii	56.19	0.00e+00	1117.00
IUUC-Oar-090068	Ovis aries	55.70	0.00e+00	1130.00
IUUC-Ptr-090609	Pan troglodytes	42.47	0.00e+00	694.00
IUUC-Pan-092114	Papio anubis	55.85	0.00e+00	1132.00
IUUC-Psi-093489	Pelodiscus sinensis	41.37	0.00e+00	703.00
IUUC-Pma-094214	Petromyzon marinus	46.75	2.00e-39	152.00
IUUC-Pno-095154	Phaeosphaeria nodorum	59.17	0.00e+00	1225.00
IUUC-Ppa-095227	Physcomitrella patens	47.45	0.00e+00	898.00
IUUC-Pfo-097184	Poecilia formosa	56.56	0.00e+00	1103.00
IUUC-Pab-097861	Pongo abelii	55.65	0.00e+00	1107.00
IUUC-Pop-098934	Populus trichocarpa	45.12	0.00e+00	890.00
IUUC-Pca-100347	Procavia capensis	53.52	0.00e+00	931.00
IUUC-Ppe-102012	Prunus persica	45.94	0.00e+00	903.00
IUUC-Pva-102584	Pteropus vampyrus	56.15	0.00e+00	1163.00
IUUC-Pgr-103336	Puccinia graminis	62.51	0.00e+00	1244.00
IUUC-Ptt-103939	Puccinia triticina	62.51	0.00e+00	1240.00
IUUC-Pte-104200	Pyrenophora teres	59.92	0.00e+00	1237.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	58.89	0.00e+00	1226.00
IUUC-Rno-105462	Rattus norvegicus	55.63	0.00e+00	1126.00
IUUC-Sce-106245	Saccharomyces cerevisiae	55.81	0.00e+00	1130.00
IUUC-Sha-107142	Sarcophilus harrisii	55.75	0.00e+00	1128.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	59.62	0.00e+00	1237.00
IUUC-Spo-108034	Schizosaccharomyces pombe	58.29	0.00e+00	1189.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	59.94	0.00e+00	1207.00
IUUC-Smo-109211	Selaginella moellendorffii	47.40	0.00e+00	892.00
IUUC-Sit-110281	Setaria italica	45.17	0.00e+00	883.00
IUUC-Sly-110914	Solanum lycopersicum	45.50	0.00e+00	907.00
IUUC-Stu-112109	Solanum tuberosum	45.30	0.00e+00	904.00
IUUC-Sar-113737	Sorex araneus	55.85	0.00e+00	1135.00
IUUC-Sbi-114520	Sorghum bicolor	45.34	0.00e+00	887.00
IUUC-Sre-115148	Sporisorium reilianum	65.29	0.00e+00	1323.00
IUUC-Ssc-115777	Sus scrofa	55.95	0.00e+00	1137.00
IUUC-Tgu-116565	Taeniopygia guttata	42.38	0.00e+00	699.00
IUUC-Tru-118742	Takifugu rubripes	57.38	0.00e+00	1079.00
IUUC-Tsy-119436	Tarsius syrichta	37.64	9.00e-167	578.00
IUUC-Tni-120401	Tetraodon nigroviridis	57.26	0.00e+00	1084.00
IUUC-Tca-121672	Theobroma cacao	44.82	0.00e+00	899.00
IUUC-Tre-122009	Trichoderma reesei	59.75	0.00e+00	1155.00
IUUC-Tvi-122259	Trichoderma virens	60.76	0.00e+00	1177.00
IUUC-Tae-125113	Triticum aestivum	44.71	0.00e+00	820.00
IUUC-Tur-126189	Triticum urartu	44.80	0.00e+00	820.00
IUUC-Tme-127055	Tuber melanosporum	58.56	0.00e+00	1159.00
IUUC-Tbe-127587	Tupaia belangeri	42.70	1.00e-157	548.00
IUUC-Ttr-128331	Tursiops truncatus	55.65	0.00e+00	1118.00
IUUC-Uma-129387	Ustilago maydis	66.11	0.00e+00	1321.00
IUUC-Vda-129977	Verticillium dahliae	58.90	0.00e+00	1149.00
IUUC-Vpa-130716	Vicugna pacos	40.22	0.00e+00	665.00
IUUC-Vvi-131026	Vitis vinifera	45.53	0.00e+00	911.00
IUUC-Xtr-132947	Xenopus tropicalis	37.86	0.00e+00	641.00
IUUC-Xma-133805	Xiphophorus maculatus	56.56	0.00e+00	1088.00
IUUC-Yli-134547	Yarrowia lipolytica	58.43	0.00e+00	1212.00
IUUC-Zma-135052	Zea mays	45.11	0.00e+00	882.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence