iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049947

Ensembl Protein ID

ENSLACP00000012404.1

UniProt Accession

H3ARY3; H3ARY3_LATCH

Genbank Protein ID

ENSLACP00000012404

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01133206

Gene Name

UBA7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000010924.1	ENSLACT00000012497.1	ENSLACP00000012404.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.00e-197	657.5	411	890

Active Site

Position(s)	Description	Evidence
591	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkel 84
           YD+Qi+++G+  q+kl ++k+++vGag++GcEllK ++++G+     g+itv+Dmd +e snlnrqFLfr++d+ k K+evaa+a++++
   Q: 411  YDGQIAVFGAAFQRKLAKQKYFMVGAGAIGCELLKIFAMIGLateegGNITVTDMDSIERSNLNRQFLFRDKDIMKLKSEVAAAAVRKM 499
           ***************************************************************************************** PP
   S: 85   npdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkt 170
           np+v+v++h++++ +++e+ +   F++ +d+ ++aldn+e+r +++ +c+ +r+pl+esgtlG++G++++i++ lt +y +   +p+k+
   Q: 500  NPNVRVVSHQNRVGPDTEHFYtdeFYEGLDGLANALDNVETRVYMDGRCVCYRKPLLESGTLGTKGNTQIIVPFLTKSYGSF-HDPEKS 587
           *******************999******************************************************887665.67899* PP
   S: 171  iPfctlketpnaaehtiewa............vlfnklleeeageeevleklds.eekeegkdkvkselksedeenfeeaieiavkafa 246
           iP+ctl+ +p+ +eht++wa            + +n++l++ ++  ++l  l++   ++e  +   ++l+se++ ++ +++++a+++++
   Q: 588  IPLCTLRYFPSSIEHTLQWArdefeglfkqpaETVNQFLQDPPCNYQTLRTLNRdPGFLEQPETLYKSLVSEKPASWFKCVTWARNHWQ 676
           ********************************************9999998887257888888889999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv............................................................. 274
           + ++n+i+qll+sf++d+vtks+ pfw                                                              
   Q: 677  NLYNNNIRQLLHSFPPDQVTKSGFPFWAgpkrcphplefsvnnpthmdyivaaanlfaetygiqgsqdratiadllkivhlpeftpksg 765
           ****************************************************9999999999999998888888888876663222222 PP
   S: 275  .sfcsnaealqvpekvekdeevvkasap...lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddl 357
            +       +   +++++d+e ++++ +   l+   ++l  +++     ++ ++fekddd   ++d++ aa+nlrae+++i+p +d+++
   Q: 766  vK-------I---PTNDQDMEDSSEQLDdenLKETREKLTALKSS-FHMMQPINFEKDDDTnfHMDFIVAASNLRAENYDIPP-ADRHK 842
           11.......2...33333444333333322133333333333333.3345689******************************.***** PP
   S: 358  ikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfda 403
            k iag+iipaiatt+a+v Gl+++E++Kv++g  + + ++n f++ a
   Q: 843  SKLIAGKIIPAIATTTAAVVGLVCLELYKVIQGhqRITSYRNSFINMA 890
           *********************************877788*****9966 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MASTENTEDI DESLYSRQLY VLGHEAMRRM KASNILISGM KGLGVEIAKN VILAGVNSVT 60
LHDEGDTQWS DLSSQFYLSE EDIGKNRALA SERQLAELNS YVHVMAYTKG LSQDFLSKFQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAAGTA CTGAAAACAC AGAGGATATT GATGAAAGCC TCTACTCTCG CCAACTGTAA 60
GCTTTGAAAC GGTTTTCTTT TTGTTTTCTT TCTTTTCTTC TTTGGATTCT TTCCCCTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence