iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090008

Ensembl Protein ID

ENSOARP00000005095.1

UniProt Accession

W5P3U3; W5P3U3_SHEEP

Genbank Protein ID

ENSOARP00000005095

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AMGL01045538

Gene Name

BAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000004753.1	ENSOART00000005181.1	ENSOARP00000005095.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	4.30e-170	565.9	3	708

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 6    kewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqv 94
           k+wleLesdPglftllvedfgvk++ qvee+y+L++++    q+pv+g+++lFk++e+r+s+rk++++++d++v+d+di++++ffa+q+
   Q: 3    KGWLELESDPGLFTLLVEDFGVKGV-QVEEIYDLQSKC----QGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQL 86
           89***********************.************....*********************************************** PP
   S: 95   igNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsy 183
           i+NsCat+Allsvllnc+++  dlG+tlsr+k++tk++spe+k++a+gn+++l+++hns+ar+e+r++pe+q+++++++t+eafhfvsy
   Q: 87   IPNSCATHALLSVLLNCSNV--DLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSY 173
           ******************99..******************************************************************* PP
   S: 184  vningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkid......... 259
           v+i+grl+eldglk++P+d+g+++e+ee++dk+++v+  +eri+l++++e    irfnl+a+v+drr+++++rl+vlk++         
   Q: 174  VPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRIKYEARLHVLKVNrqtvlealq 260
           *************************************..************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 261  qlirvtqpeliqthksqesqlpeesnpassksplaletsrapvasesthtdgveevagscpqapthsppskpklvvkppgsningvppn 349
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 350  ptpivqrlpafldnhnyakspmqeeedlaagvgrsrvpvqstsstirykrkgpgkpgplsssgdgqlsvlqpntisvlaekltesqkdl 438
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 439  siplsiktssgagspavavpthsqpsptpsnestdtaseigsafnsplrspirsanptrpsspvtshiskvlfgeddsllrvdcirynr 527
           ***************************************************************************************** PP
   S: 260  .................................................................................keLlkLlk 267
                                                                                            keLl+Llk
   Q: 528  avrdlgpvistgllhlaedgvlsplaltesgkgsspsirpsqgsqgsgspeekevveavdsrekpglvrpseplngekyspKELLALLK 616
           ***************************************************************************************** PP
   S: 268  dieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveetisevrefgvnegrlakqrkqgrekkirplkr 356
           ++e+e++++ea+l++e+ekrkkfkidd+rRt+nydefic+fi++la+eg+l++lve++is++r++gv++grl+kqrk++r+k++rp+k+
   Q: 617  CVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKA 705
           ***************************************************************************************** PP
   S: 357  krk 359
           kr+
   Q: 706  KRQ 708
           *97 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MNKGWLELES DPGLFTLLVE DFGVKGVQVE EIYDLQSKCQ GPVYGFIFLF KWIEERRSRR 60
KVSTLVDDTS VIDDDIVNNM FFAHQLIPNS CATHALLSVL LNCSNVDLGP TLSRMKDFTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATAAGG GCTGGCTGGA GCTGGAGAGC GACCCTGGTG AGAAGGGGAT CGGGCAGGCC 60
GGGAGTTGGG GAGGCCGGGT GGGTCCGAGA CGCGCCTTTC TGATCACCAC TCGCTCCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

oas:101111666

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001263	Ailuropoda melanoleuca	91.30	0.00e+00	1186.00
IUUC-Apl-003405	Anas platyrhynchos	66.05	7.00e-177	613.00
IUUC-Aca-004836	Anolis carolinensis	78.16	0.00e+00	1130.00
IUUC-Ame-011946	Astyanax mexicanus	62.66	0.00e+00	890.00
IUUC-Bta-013131	Bos taurus	92.71	0.00e+00	1085.00
IUUC-Cja-019599	Callithrix jacchus	93.42	0.00e+00	1311.00
IUUC-Cfa-021003	Canis familiaris	93.55	0.00e+00	1187.00
IUUC-Cpo-022143	Cavia porcellus	92.32	0.00e+00	1274.00
IUUC-Csa-023477	Chlorocebus sabaeus	92.46	0.00e+00	1271.00
IUUC-Cho-024734	Choloepus hoffmanni	82.23	0.00e+00	759.00
IUUC-Csv-025842	Ciona savignyi	58.22	6.00e-95	340.00
IUUC-Dre-027793	Danio rerio	64.84	0.00e+00	907.00
IUUC-Dno-029253	Dasypus novemcinctus	91.55	0.00e+00	1260.00
IUUC-Dor-030891	Dipodomys ordii	86.28	0.00e+00	1191.00
IUUC-Dme-031796	Drosophila melanogaster	61.19	1.00e-92	333.00
IUUC-Ete-032646	Echinops telfairi	81.40	3.00e-166	578.00
IUUC-Eca-033805	Equus caballus	93.14	0.00e+00	1243.00
IUUC-Eeu-035216	Erinaceus europaeus	93.54	2.00e-151	529.00
IUUC-Fca-035611	Felis catus	92.90	0.00e+00	1133.00
IUUC-Fal-037186	Ficedula albicollis	77.88	0.00e+00	980.00
IUUC-Gmo-038824	Gadus morhua	67.71	8.00e-178	617.00
IUUC-Gga-040875	Gallus gallus	79.59	0.00e+00	1101.00
IUUC-Gac-042226	Gasterosteus aculeatus	66.89	0.00e+00	933.00
IUUC-Ggo-045122	Gorilla gorilla	92.18	0.00e+00	1305.00
IUUC-Hsa-045882	Homo sapiens	91.91	0.00e+00	1301.00
IUUC-Itr-048185	Ictidomys tridecemlineatus	93.42	0.00e+00	1291.00
IUUC-Lch-049960	Latimeria chalumnae	71.68	0.00e+00	995.00
IUUC-Loc-052408	Lepisosteus oculatus	72.25	0.00e+00	647.00
IUUC-Laf-054187	Loxodonta africana	93.42	0.00e+00	1228.00
IUUC-Mcc-055273	Macaca mulatta	91.36	0.00e+00	1267.00
IUUC-Meu-056267	Macropus eugenii	79.97	0.00e+00	1146.00
IUUC-Mga-059958	Meleagris gallopavo	88.89	1.00e-155	542.00
IUUC-Mmr-061280	Microcebus murinus	93.29	0.00e+00	1263.00
IUUC-Mdo-062625	Monodelphis domestica	87.38	0.00e+00	1257.00
IUUC-Mmu-063853	Mus musculus	91.76	0.00e+00	1262.00
IUUC-Mlu-067771	Myotis lucifugus	92.46	0.00e+00	1217.00
IUUC-Opr-070741	Ochotona princeps	91.08	0.00e+00	1258.00
IUUC-Ont-072172	Oreochromis niloticus	65.06	0.00e+00	939.00
IUUC-Oan-073167	Ornithorhynchus anatinus	79.94	0.00e+00	1130.00
IUUC-Ocu-074176	Oryctolagus cuniculus	92.02	0.00e+00	1205.00
IUUC-Ola-087203	Oryzias latipes	85.23	3.00e-135	474.00
IUUC-Oga-089153	Otolemur garnettii	92.11	0.00e+00	1265.00
IUUC-Ptr-091234	Pan troglodytes	92.18	0.00e+00	1307.00
IUUC-Pan-092005	Papio anubis	92.46	0.00e+00	1295.00
IUUC-Psi-093995	Pelodiscus sinensis	84.90	0.00e+00	662.00
IUUC-Pma-094110	Petromyzon marinus	49.75	2.00e-120	426.00
IUUC-Pfo-097418	Poecilia formosa	65.09	0.00e+00	917.00
IUUC-Pab-098267	Pongo abelii	92.04	0.00e+00	1280.00
IUUC-Pca-101084	Procavia capensis	91.68	0.00e+00	1186.00
IUUC-Pva-102292	Pteropus vampyrus	91.65	0.00e+00	885.00
IUUC-Rno-105251	Rattus norvegicus	90.27	0.00e+00	1236.00
IUUC-Sha-107100	Sarcophilus harrisii	85.83	0.00e+00	1248.00
IUUC-Sar-113559	Sorex araneus	84.59	0.00e+00	1058.00
IUUC-Ssc-115688	Sus scrofa	92.73	0.00e+00	1279.00
IUUC-Tgu-117424	Taeniopygia guttata	78.54	0.00e+00	1105.00
IUUC-Tru-118585	Takifugu rubripes	66.62	0.00e+00	931.00
IUUC-Tsy-119299	Tarsius syrichta	80.79	0.00e+00	950.00
IUUC-Tni-120808	Tetraodon nigroviridis	66.40	0.00e+00	927.00
IUUC-Tbe-127705	Tupaia belangeri	95.43	0.00e+00	637.00
IUUC-Ttr-128225	Tursiops truncatus	93.42	0.00e+00	1231.00
IUUC-Vpa-130193	Vicugna pacos	96.03	4.00e-130	458.00
IUUC-Xtr-132449	Xenopus tropicalis	72.08	0.00e+00	949.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence