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Tag Content
iUUCD ID IUUC-Ptr-090857
Ensembl Protein ID ENSPTRP00000051478.3
UniProt Accession H2R8D7; H2R8D7_PANTR
Genbank Protein ID ENSPTRP00000051478
Protein Name Tyrosine-protein kinase
Genbank Nucleotide ID AACZ03000524
Gene Name ABL2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPTRG00000001727.5 ENSPTRT00000058473.3 ENSPTRP00000051478.3
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.80e-12 47.0 109 166
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 109  PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 166
           67899************************.*********98..788899*********997 PP
   
Organism Pan troglodytes
Protein Sequence
(Fasta)
MGQQVGRVGE APGLQQPQPR GIRGSSAARP SGRRRDPAGR TTETGFNIFT QHDHFASCVE 60
DGFEGDKTGG SSPEALHRPY GCDVEPQALN EAIRWSSKEN LLGATESDPN LFVALYDFVA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ptr-090857|UBD,SH3|Pan troglodytes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGGGCAGC AGGTGGGCCG CGTCGGGGAA GCTCCGGGGC TCCAGCAGCC TCAGCCCCGC 60
GGGATCCGGG GCAGCAGTGC AGCCAGGCCC TCCGGCCGCA GGCGGGACCC GGCGGGGCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ptr-090857|UBD,SH3|Pan troglodytes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE
SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0071300--P:cellular response to retinoic acid
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002263 Ailuropoda melanoleuca 99.19 0.00e+00 1253.00
IUUC-Atr-002778 Amborella trichopoda 32.49 9.00e-23 102.00
IUUC-Apl-003389 Anas platyrhynchos 96.42 0.00e+00 1224.00
IUUC-Bta-013370 Bos taurus 97.67 0.00e+00 1324.00
IUUC-Cja-018894 Callithrix jacchus 96.75 0.00e+00 1259.00
IUUC-Cfa-020398 Canis familiaris 97.37 0.00e+00 1888.00
IUUC-Cpo-022367 Cavia porcellus 97.24 0.00e+00 1225.00
IUUC-Csa-023386 Chlorocebus sabaeus 99.84 0.00e+00 1262.00
IUUC-Cho-024714 Choloepus hoffmanni 98.21 0.00e+00 1212.00
IUUC-Dre-027741 Danio rerio 80.71 0.00e+00 1071.00
IUUC-Dno-029246 Dasypus novemcinctus 95.34 0.00e+00 1284.00
IUUC-Dor-030416 Dipodomys ordii 88.65 0.00e+00 1173.00
IUUC-Ete-032899 Echinops telfairi 90.62 6.00e-147 515.00
IUUC-Eca-033387 Equus caballus 97.99 0.00e+00 1299.00
IUUC-Eeu-035058 Erinaceus europaeus 85.59 0.00e+00 1137.00
IUUC-Fca-036578 Felis catus 98.36 0.00e+00 1194.00
IUUC-Fal-037491 Ficedula albicollis 96.74 0.00e+00 1224.00
IUUC-Gmo-038509 Gadus morhua 86.94 0.00e+00 1048.00
IUUC-Gga-040638 Gallus gallus 92.06 0.00e+00 1213.00
IUUC-Gac-042550 Gasterosteus aculeatus 86.79 0.00e+00 1067.00
IUUC-Ggo-044487 Gorilla gorilla 99.85 0.00e+00 1366.00
IUUC-Hsa-046636 Homo sapiens 99.85 0.00e+00 1367.00
IUUC-Itr-048685 Ictidomys tridecemlineatus 98.43 0.00e+00 1290.00
IUUC-Lch-049530 Latimeria chalumnae 84.39 0.00e+00 1185.00
IUUC-Loc-051933 Lepisosteus oculatus 85.40 0.00e+00 1136.00
IUUC-Laf-053802 Loxodonta africana 97.10 0.00e+00 1407.00
IUUC-Mcc-054836 Macaca mulatta 99.85 0.00e+00 1365.00
IUUC-Mga-059277 Meleagris gallopavo 96.25 0.00e+00 1222.00
IUUC-Mmr-061206 Microcebus murinus 97.53 0.00e+00 1347.00
IUUC-Mdo-062281 Monodelphis domestica 89.71 0.00e+00 1810.00
IUUC-Mmu-063847 Mus musculus 95.49 0.00e+00 1261.00
IUUC-Mpu-066309 Mustela putorius furo 96.94 0.00e+00 1930.00
IUUC-Mlu-068070 Myotis lucifugus 98.05 0.00e+00 1231.00
IUUC-Nle-070062 Nomascus leucogenys 99.26 0.00e+00 2001.00
IUUC-Ont-072440 Oreochromis niloticus 78.86 0.00e+00 1067.00
IUUC-Oan-073526 Ornithorhynchus anatinus 96.25 0.00e+00 1220.00
IUUC-Ocu-074051 Oryctolagus cuniculus 97.24 0.00e+00 1224.00
IUUC-Opu-083538 Oryza punctata 34.39 5.00e-23 102.00
IUUC-Oga-088767 Otolemur garnettii 88.17 0.00e+00 1086.00
IUUC-Oar-089800 Ovis aries 98.54 0.00e+00 1223.00
IUUC-Pan-092279 Papio anubis 96.80 0.00e+00 1307.00
IUUC-Psi-093573 Pelodiscus sinensis 95.95 0.00e+00 1218.00
IUUC-Pfo-096543 Poecilia formosa 76.08 0.00e+00 1045.00
IUUC-Pab-097949 Pongo abelii 96.65 0.00e+00 1307.00
IUUC-Pca-100370 Procavia capensis 98.91 0.00e+00 765.00
IUUC-Pva-103220 Pteropus vampyrus 86.46 0.00e+00 1184.00
IUUC-Rno-105924 Rattus norvegicus 93.45 0.00e+00 1234.00
IUUC-Sha-107114 Sarcophilus harrisii 94.96 0.00e+00 1174.00
IUUC-Sit-110219 Setaria italica 30.30 5.00e-20 93.20
IUUC-Ssc-115968 Sus scrofa 98.54 0.00e+00 1356.00
IUUC-Tgu-117301 Taeniopygia guttata 96.27 0.00e+00 1222.00
IUUC-Tru-118410 Takifugu rubripes 79.02 0.00e+00 1115.00
IUUC-Tni-119991 Tetraodon nigroviridis 78.92 0.00e+00 1110.00
IUUC-Tca-121389 Theobroma cacao 33.85 1.00e-23 105.00
IUUC-Tbe-127362 Tupaia belangeri 98.84 0.00e+00 1313.00
IUUC-Ttr-129291 Tursiops truncatus 98.86 0.00e+00 1246.00
IUUC-Vpa-130800 Vicugna pacos 95.92 0.00e+00 1240.00
IUUC-Xtr-132965 Xenopus tropicalis 86.55 0.00e+00 1179.00
Created Date 25-Jun-2017

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