iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116778

Ensembl Protein ID

ENSTGUP00000012160.1

UniProt Accession

H0ZNI4; H0ZNI4_TAEGU

Genbank Protein ID

ENSTGUP00000012160

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01036070

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000011797.1	ENSTGUT00000012294.1	ENSTGUP00000012160.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	88.25	0.00e+00	844.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

IKMVDTENQL YPLTPLEEED IDSPLSGEFL QDMENIQDLS QSLGDDSSGA LSLTEFQSLG 60
NGPGSDGSVI TDTLSPASSP SSINFATAPG SIDESPSGAL NIECRICGDK ASGYHYGVHA 120

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Nucleotide Sequence
(Fasta)

ATCAAAATGG TGGACACTGA AAACCAGCTC TATCCCCTTA CTCCCTTGGA GGAGGAGGAT 60
ATAGACAGCC CTTTATCTGG AGAGTTCCTA CAAGATATGG AGAACATTCA AGACCTGTCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	86.23	0.00e+00	858.00
IUUC-Apl-003330	Anas platyrhynchos	96.62	0.00e+00	919.00
IUUC-Aca-004598	Anolis carolinensis	89.15	0.00e+00	855.00
IUUC-Acl-008339	Aspergillus clavatus	45.45	1.10e-01	29.60
IUUC-Ame-011508	Astyanax mexicanus	72.98	0.00e+00	700.00
IUUC-Bta-012621	Bos taurus	87.45	0.00e+00	841.00
IUUC-Cja-019688	Callithrix jacchus	88.25	0.00e+00	842.00
IUUC-Cfa-020859	Canis familiaris	87.18	0.00e+00	858.00
IUUC-Cpo-021607	Cavia porcellus	82.05	0.00e+00	786.00
IUUC-Csa-023313	Chlorocebus sabaeus	87.82	0.00e+00	836.00
IUUC-Cho-024741	Choloepus hoffmanni	76.92	0.00e+00	700.00
IUUC-Dre-027446	Danio rerio	71.91	0.00e+00	686.00
IUUC-Dno-029173	Dasypus novemcinctus	86.60	0.00e+00	828.00
IUUC-Dor-030581	Dipodomys ordii	83.94	0.00e+00	780.00
IUUC-Dme-031794	Drosophila melanogaster	35.10	6.00e-57	216.00
IUUC-Ete-032330	Echinops telfairi	84.40	0.00e+00	820.00
IUUC-Eca-033712	Equus caballus	87.45	0.00e+00	827.00
IUUC-Fca-036555	Felis catus	87.45	0.00e+00	860.00
IUUC-Fal-036677	Ficedula albicollis	99.15	0.00e+00	925.00
IUUC-Gmo-039240	Gadus morhua	81.55	0.00e+00	641.00
IUUC-Gga-040473	Gallus gallus	97.86	0.00e+00	922.00
IUUC-Gac-041872	Gasterosteus aculeatus	71.46	0.00e+00	701.00
IUUC-Ggo-045226	Gorilla gorilla	88.25	0.00e+00	841.00
IUUC-Hsa-046893	Homo sapiens	88.25	0.00e+00	841.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	85.26	0.00e+00	816.00
IUUC-Lch-050116	Latimeria chalumnae	79.91	0.00e+00	766.00
IUUC-Loc-052131	Lepisosteus oculatus	83.00	0.00e+00	689.00
IUUC-Laf-054323	Loxodonta africana	87.18	0.00e+00	831.00
IUUC-Mcc-054841	Macaca mulatta	87.87	0.00e+00	839.00
IUUC-Meu-056833	Macropus eugenii	78.21	0.00e+00	716.00
IUUC-Mga-059995	Meleagris gallopavo	87.50	0.00e+00	815.00
IUUC-Mmr-060576	Microcebus murinus	56.05	1.00e-147	515.00
IUUC-Mdo-061954	Monodelphis domestica	87.00	0.00e+00	765.00
IUUC-Mmu-064295	Mus musculus	83.55	0.00e+00	783.00
IUUC-Mpu-066216	Mustela putorius furo	87.61	0.00e+00	863.00
IUUC-Mlu-067978	Myotis lucifugus	63.41	1.00e-151	529.00
IUUC-Nle-069970	Nomascus leucogenys	88.03	0.00e+00	838.00
IUUC-Opr-070630	Ochotona princeps	65.32	4.00e-116	410.00
IUUC-Ont-071594	Oreochromis niloticus	73.15	0.00e+00	699.00
IUUC-Oan-073501	Ornithorhynchus anatinus	90.46	0.00e+00	755.00
IUUC-Ocu-074634	Oryctolagus cuniculus	77.34	0.00e+00	778.00
IUUC-Oni-082926	Oryza nivara	30.19	2.50e-02	29.30
IUUC-Ola-086585	Oryzias latipes	79.37	0.00e+00	637.00
IUUC-Oga-088738	Otolemur garnettii	88.72	0.00e+00	844.00
IUUC-Oar-090453	Ovis aries	87.66	0.00e+00	843.00
IUUC-Ptr-091518	Pan troglodytes	88.03	0.00e+00	834.00
IUUC-Pan-092006	Papio anubis	88.03	0.00e+00	834.00
IUUC-Psi-093352	Pelodiscus sinensis	90.47	0.00e+00	868.00
IUUC-Ppa-095660	Physcomitrella patens	31.15	3.30e-01	30.80
IUUC-Pfo-096060	Poecilia formosa	72.09	0.00e+00	694.00
IUUC-Pab-098602	Pongo abelii	81.86	0.00e+00	739.00
IUUC-Pca-100861	Procavia capensis	65.17	2.00e-144	505.00
IUUC-Pva-102175	Pteropus vampyrus	82.69	0.00e+00	806.00
IUUC-Rno-105283	Rattus norvegicus	84.40	0.00e+00	785.00
IUUC-Sce-106436	Saccharomyces cerevisiae	29.03	3.80e-02	29.30
IUUC-Sha-106560	Sarcophilus harrisii	88.27	0.00e+00	847.00
IUUC-Smo-109075	Selaginella moellendorffii	28.00	2.80e-01	28.10
IUUC-Sar-112996	Sorex araneus	54.07	2.00e-111	395.00
IUUC-Ssc-115266	Sus scrofa	86.75	0.00e+00	863.00
IUUC-Tru-118436	Takifugu rubripes	71.04	0.00e+00	694.00
IUUC-Tsy-119642	Tarsius syrichta	75.21	0.00e+00	697.00
IUUC-Tni-119859	Tetraodon nigroviridis	71.88	0.00e+00	697.00
IUUC-Tvi-122624	Trichoderma virens	29.63	4.20e-01	26.90
IUUC-Tbe-127464	Tupaia belangeri	87.39	0.00e+00	856.00
IUUC-Ttr-129307	Tursiops truncatus	83.80	0.00e+00	779.00
IUUC-Vpa-130378	Vicugna pacos	61.25	3.00e-115	408.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence