iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034241

UUCD1 version

UUC-EqC-00540

Ensembl Protein ID

ENSECAP00000021979.1

UniProt Accession

F6YV64; F6YV64_HORSE

Protein Name

Uncharacterized protein

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024467.1	ENSECAT00000026355.1	ENSECAP00000021979.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.30e-08	32.7	12	53
UBD/SH3	1.20e-31	108.7	386	440

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+e ++   +vlpC+H+f++ Clq++     ++ ke rCP Cr
   Q: 12   CPVCFEKLDVTAKVLPCQHTFCKPCLQRI----FKAHKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + + +l++y+a   deL l+kG+ ++v+   +   gWl+gv+  +g+ G+fP+n+v 
   Q: 386  NMFVALHSYSAHGPDELDLQKGEGIRVL--GKYQDGWLRGVSLVTGRVGIFPNNYVI 440
           7889************************..555679*******************96 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MDDLTLLDLL ECPVCFEKLD VTAKVLPCQH TFCKPCLQRI FKAHKELRCP ECRTLVFCSI 60
EALPANLLLV RLLDGVRSGQ SAGRAGSFRR PGVLTSQDSR KSRTSPRGLQ SSPFRLVPNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTCATACA GGCAGGAATT CTGAGGCTCT CAAGAGACCG GCTCTGCCCC CTTGGCTCAG 60
CTGACCCTAC AATGCGGACT CTGCCTTTCC AGGTCAGGAC TGGAGCTTTA AAATAAAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PF00097--zf-C3HC4

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

KEGG

ecb:100071998

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	90.67	0.00e+00	1167.00
IUUC-Apl-003443	Anas platyrhynchos	62.19	0.00e+00	637.00
IUUC-Aca-004632	Anolis carolinensis	57.29	0.00e+00	627.00
IUUC-Bta-013400	Bos taurus	92.17	0.00e+00	1140.00
IUUC-Cel-018180	Caenorhabditis elegans	27.59	6.00e-22	99.80
IUUC-Cja-019686	Callithrix jacchus	77.27	0.00e+00	971.00
IUUC-Cfa-020893	Canis familiaris	92.81	0.00e+00	1179.00
IUUC-Cpo-021638	Cavia porcellus	84.16	0.00e+00	1079.00
IUUC-Csa-023846	Chlorocebus sabaeus	90.03	0.00e+00	1164.00
IUUC-Cho-024609	Choloepus hoffmanni	89.21	4.00e-178	617.00
IUUC-Cin-025274	Ciona intestinalis	48.43	9.00e-63	233.00
IUUC-Csv-026136	Ciona savignyi	45.22	4.00e-62	231.00
IUUC-Dno-028940	Dasypus novemcinctus	88.71	0.00e+00	1146.00
IUUC-Dor-030491	Dipodomys ordii	81.45	8.00e-138	484.00
IUUC-Dse-031414	Dothistroma septosporum	34.33	3.00e-08	54.70
IUUC-Dme-032207	Drosophila melanogaster	41.15	5.00e-53	202.00
IUUC-Ete-032513	Echinops telfairi	87.21	0.00e+00	1114.00
IUUC-Eeu-034636	Erinaceus europaeus	83.24	0.00e+00	984.00
IUUC-Fca-035862	Felis catus	89.36	0.00e+00	1162.00
IUUC-Gga-040748	Gallus gallus	55.79	6.00e-155	541.00
IUUC-Ggo-045267	Gorilla gorilla	90.86	0.00e+00	1172.00
IUUC-Hsa-045761	Homo sapiens	90.44	0.00e+00	1164.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	87.53	0.00e+00	1119.00
IUUC-Lch-050498	Latimeria chalumnae	44.72	5.00e-125	441.00
IUUC-Laf-054061	Loxodonta africana	81.30	0.00e+00	874.00
IUUC-Mcc-054746	Macaca mulatta	89.29	0.00e+00	1118.00
IUUC-Meu-056390	Macropus eugenii	62.23	2.00e-99	356.00
IUUC-Mmr-061390	Microcebus murinus	85.64	0.00e+00	920.00
IUUC-Mdo-062951	Monodelphis domestica	74.49	0.00e+00	1025.00
IUUC-Mmu-063840	Mus musculus	81.54	0.00e+00	1065.00
IUUC-Mpu-065840	Mustela putorius furo	91.15	0.00e+00	1206.00
IUUC-Mlu-067378	Myotis lucifugus	88.05	0.00e+00	1104.00
IUUC-Nle-069535	Nomascus leucogenys	86.84	0.00e+00	1088.00
IUUC-Opr-070739	Ochotona princeps	83.66	0.00e+00	1063.00
IUUC-Oan-073468	Ornithorhynchus anatinus	67.36	0.00e+00	826.00
IUUC-Ocu-074343	Oryctolagus cuniculus	85.71	0.00e+00	1061.00
IUUC-Oga-088276	Otolemur garnettii	81.44	0.00e+00	1033.00
IUUC-Oar-090315	Ovis aries	90.23	0.00e+00	1124.00
IUUC-Ptr-091119	Pan troglodytes	90.30	0.00e+00	1163.00
IUUC-Pan-092158	Papio anubis	91.10	0.00e+00	851.00
IUUC-Psi-092959	Pelodiscus sinensis	61.14	0.00e+00	777.00
IUUC-Pab-097675	Pongo abelii	90.44	0.00e+00	1148.00
IUUC-Pca-101021	Procavia capensis	81.35	0.00e+00	1026.00
IUUC-Pva-102619	Pteropus vampyrus	91.54	0.00e+00	1140.00
IUUC-Rno-105918	Rattus norvegicus	81.13	0.00e+00	1064.00
IUUC-Sha-107391	Sarcophilus harrisii	69.71	0.00e+00	933.00
IUUC-Sar-113148	Sorex araneus	83.45	0.00e+00	666.00
IUUC-Ssc-116219	Sus scrofa	87.32	9.00e-141	492.00
IUUC-Tgu-116584	Taeniopygia guttata	58.37	3.00e-117	415.00
IUUC-Tsy-118968	Tarsius syrichta	83.51	9.00e-172	597.00
IUUC-Tbe-128007	Tupaia belangeri	92.17	0.00e+00	845.00
IUUC-Ttr-128499	Tursiops truncatus	89.61	0.00e+00	1173.00
IUUC-Vpa-130075	Vicugna pacos	86.36	2.00e-82	300.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence