iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-025921

UUCD1 version

UUC-CiS-00001

Ensembl Protein ID

ENSCSAVP00000007270.1

UniProt Accession

H2YPL2; H2YPL2_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000004341.1	ENSCSAVT00000007362.1	ENSCSAVP00000007268.1
ENSCSAVG00000004341.1	ENSCSAVT00000007363.1	ENSCSAVP00000007269.1
ENSCSAVG00000004341.1	ENSCSAVT00000007364.1	ENSCSAVP00000007270.1
ENSCSAVG00000004341.1	ENSCSAVT00000007365.1	ENSCSAVP00000007271.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	3.80e-140	466.4	196	508
E3 adaptor/Cullin RING/DCX/DWD	9.40e-26	88.8	336	367

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekk 87
           p+k+ldapel+ddfylnL+dWss+nvl+v+Lg++vylwsa+t++v++l+dl +++d+vtsv+w ++g+l+avGt+kg v+++D+ ++k
   Q: 196  PFKILDAPELQDDFYLNLVDWSSSNVLSVGLGACVYLWSACTSQVIRLCDLgTDGDSVTSVNWNDRGNLVAVGTHKGYVQVWDALANK 283
           689************************************************99*********************************** PP
   S: 88   kvrtltghsarvgaLsWnaevlssGsrdgeilhrdvr.....vkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse 170
           k+++l+gh+ rvgaL+Wn ++lssGsrd+ il+rd+r     +++++ ++l +h+qevCGlkw+ d+++LasGGnDn + vw+as+s+
   Q: 284  KIKQLEGHTYRVGALAWNGDQLSSGSRDRIILQRDIRsssatAPGNSDRKLVGHRQEVCGLKWSPDQQHLASGGNDNRLLVWNASTSS 371
           *************************************888866777779**********************************99887 PP
   S: 171  .....PlkkfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwk 253
                P +++ eh aavkaiawsP+q++lLasGGGtaDrci+fwntlt + l+++dtgsqvc+l+wsk+++elvsthG+++n+i lwk
   Q: 372  anqsqPAQTYCEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTQQPLQCVDTGSQVCNLAWSKHASELVSTHGYSQNQILLWK 459
           78888*********************************************************************************** PP
   S: 254  ypslskvaelkgheaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           ypsl++va+l+gh++Rvl+la spdgeaivt+agDetlrfw++f+k+++
   Q: 460  YPSLKQVAKLTGHTYRVLYLATSPDGEAIVTGAGDETLRFWNVFSKSPS 508
           *********************************************9876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH  +v++l++ +d  +l+sG++D+ + vW+ 
   Q: 336  GHRQEVCGLKWsPDqQHLASGGNDNRLLVWNA 367
           8***********999***************95 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

MDQDFERRLL KQQNGPPISP TLSPSSPFGN RHHPWSMPSS PSGLSPVKPD RGSDRFIPSR 60
AGARWHIDFD LIYEKGQGRS PSKPNNNQQN TNQANTPQTN QQQQQQSPQH LMYQCLLRNE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTGAGAAG CGCGATGGAT TATCTTTAAA AAGTTCTCTG CAAATAGCAA ACATTAGGAA 60
TAGTTTAGGT TGGTAACAAA TGCTGACTCA CCGTCCTCTT CACCATCTGC CGAGTCATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	60.86	5.00e-111	393.00
IUUC-Aml-002003	Ailuropoda melanoleuca	65.99	0.00e+00	660.00
IUUC-Atr-002753	Amborella trichopoda	62.57	6.00e-125	439.00
IUUC-Apl-003212	Anas platyrhynchos	66.92	0.00e+00	674.00
IUUC-Aly-005442	Arabidopsis lyrata	53.76	1.00e-130	457.00
IUUC-Ath-006938	Arabidopsis thaliana	53.43	7.00e-130	455.00
IUUC-Ago-007784	Ashbya gossypii	47.89	5.00e-93	333.00
IUUC-Acl-008269	Aspergillus clavatus	48.18	2.00e-125	441.00
IUUC-Afl-008432	Aspergillus flavus	48.37	3.00e-126	444.00
IUUC-Afu-008829	Aspergillus fumigatus	48.38	1.00e-125	441.00
IUUC-Ani-009471	Aspergillus nidulans	48.58	2.00e-127	447.00
IUUC-Ang-009711	Aspergillus niger	48.12	3.00e-123	433.00
IUUC-Aor-010118	Aspergillus oryzae	48.37	3.00e-126	444.00
IUUC-Ate-010534	Aspergillus terreus	47.98	6.00e-126	442.00
IUUC-Ame-011011	Astyanax mexicanus	65.41	0.00e+00	627.00
IUUC-Bgr-012013	Blumeria graminis	62.69	5.00e-122	429.00
IUUC-Bta-012586	Bos taurus	66.36	0.00e+00	673.00
IUUC-Bci-013807	Botrytis cinerea	47.90	3.00e-120	423.00
IUUC-Bdi-014981	Brachypodium distachyon	68.15	3.00e-125	440.00
IUUC-Bol-016301	Brassica oleracea	53.46	7.00e-131	458.00
IUUC-Bra-017453	Brassica rapa	53.46	6.00e-131	459.00
IUUC-Cel-018472	Caenorhabditis elegans	64.51	1.00e-145	508.00
IUUC-Cja-019929	Callithrix jacchus	65.99	0.00e+00	669.00
IUUC-Cfa-020977	Canis familiaris	65.61	0.00e+00	665.00
IUUC-Cpo-021537	Cavia porcellus	66.17	0.00e+00	672.00
IUUC-Csa-023389	Chlorocebus sabaeus	66.17	0.00e+00	672.00
IUUC-Cin-025327	Ciona intestinalis	78.87	0.00e+00	746.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	46.70	6.00e-125	439.00
IUUC-Cne-026933	Cryptococcus neoformans	59.60	1.00e-120	425.00
IUUC-Cme-027143	Cyanidioschyzon merolae	61.54	1.00e-113	402.00
IUUC-Dre-027470	Danio rerio	66.22	0.00e+00	633.00
IUUC-Dno-029629	Dasypus novemcinctus	78.17	8.00e-154	535.00
IUUC-Dor-030187	Dipodomys ordii	73.92	6.00e-177	612.00
IUUC-Dse-031502	Dothistroma septosporum	46.19	1.00e-117	415.00
IUUC-Dme-031858	Drosophila melanogaster	62.12	4.00e-177	612.00
IUUC-Ete-032562	Echinops telfairi	58.40	1.00e-160	557.00
IUUC-Eca-034210	Equus caballus	66.36	0.00e+00	674.00
IUUC-Fca-035839	Felis catus	65.72	0.00e+00	650.00
IUUC-Fal-036895	Ficedula albicollis	66.92	0.00e+00	674.00
IUUC-Fox-037814	Fusarium oxysporum	60.42	3.00e-117	412.00
IUUC-Fso-038420	Fusarium solani	47.00	4.00e-124	436.00
IUUC-Gmo-039544	Gadus morhua	65.40	0.00e+00	635.00
IUUC-Ggr-039774	Gaeumannomyces graminis	48.90	8.00e-126	442.00
IUUC-Gga-041025	Gallus gallus	66.73	0.00e+00	672.00
IUUC-Gac-041596	Gasterosteus aculeatus	65.21	0.00e+00	631.00
IUUC-Gma-042657	Glycine max	54.09	3.00e-130	456.00
IUUC-Ggo-045599	Gorilla gorilla	65.80	0.00e+00	637.00
IUUC-Hsa-046695	Homo sapiens	65.80	0.00e+00	667.00
IUUC-Hvu-047486	Hordeum vulgare	63.10	3.00e-102	362.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	66.60	0.00e+00	674.00
IUUC-Kpa-049239	Komagataella pastoris	43.22	6.00e-120	422.00
IUUC-Lch-049827	Latimeria chalumnae	66.92	0.00e+00	651.00
IUUC-Lpe-051568	Leersia perrieri	62.38	3.00e-106	377.00
IUUC-Loc-052856	Lepisosteus oculatus	66.36	0.00e+00	648.00
IUUC-Mcc-055601	Macaca mulatta	66.17	0.00e+00	672.00
IUUC-Meu-056276	Macropus eugenii	56.11	2.00e-140	490.00
IUUC-Mor-057113	Magnaporthe oryzae	47.21	1.00e-125	441.00
IUUC-Mpo-057599	Magnaporthe poae	48.90	2.00e-125	441.00
IUUC-Mtr-057689	Medicago truncatula	53.29	2.00e-129	454.00
IUUC-Mla-059048	Melampsora laricipopulina	48.91	4.00e-112	397.00
IUUC-Mga-060097	Meleagris gallopavo	63.08	5.00e-179	618.00
IUUC-Mvi-060465	Microbotryum violaceum	48.03	7.00e-122	429.00
IUUC-Mmr-061151	Microcebus murinus	58.74	4.00e-160	556.00
IUUC-Mdo-063062	Monodelphis domestica	66.73	0.00e+00	673.00
IUUC-Mmu-063731	Mus musculus	66.17	0.00e+00	670.00
IUUC-Mac-064942	Musa acuminata	52.75	5.00e-129	452.00
IUUC-Mpu-066173	Mustela putorius furo	65.98	0.00e+00	672.00
IUUC-Mlu-068030	Myotis lucifugus	65.80	0.00e+00	666.00
IUUC-Nfi-068536	Neosartorya fischeri	48.18	4.00e-126	443.00
IUUC-Ncr-068734	Neurospora crassa	50.10	1.00e-127	448.00
IUUC-Nle-070163	Nomascus leucogenys	66.17	0.00e+00	673.00
IUUC-Opr-070974	Ochotona princeps	77.41	1.00e-132	463.00
IUUC-Ont-072507	Oreochromis niloticus	64.64	0.00e+00	656.00
IUUC-Oan-073634	Ornithorhynchus anatinus	81.79	3.00e-146	509.00
IUUC-Oba-075417	Oryza barthii	61.44	1.00e-106	378.00
IUUC-Obr-076123	Oryza brachyantha	68.47	2.00e-123	434.00
IUUC-Ogl-077294	Oryza glaberrima	67.83	2.00e-122	430.00
IUUC-Ogu-077996	Oryza glumaepatula	67.52	3.00e-121	426.00
IUUC-Oin-080172	Oryza indica	67.83	2.00e-122	430.00
IUUC-Olo-081068	Oryza longistaminata	67.83	2.00e-122	429.00
IUUC-Ome-081250	Oryza meridionalis	67.83	2.00e-122	431.00
IUUC-Oni-083048	Oryza nivara	67.83	2.00e-122	430.00
IUUC-Opu-083333	Oryza punctata	67.83	3.00e-122	430.00
IUUC-Oru-085001	Oryza rufipogon	67.83	2.00e-122	430.00
IUUC-Osa-086243	Oryza sativa	67.83	2.00e-122	430.00
IUUC-Ola-087094	Oryzias latipes	63.14	6.00e-175	605.00
IUUC-Oga-088911	Otolemur garnettii	66.17	0.00e+00	672.00
IUUC-Oar-089508	Ovis aries	66.36	0.00e+00	673.00
IUUC-Ptr-090967	Pan troglodytes	50.11	3.00e-103	367.00
IUUC-Pan-092147	Papio anubis	65.80	0.00e+00	667.00
IUUC-Psi-093702	Pelodiscus sinensis	66.42	0.00e+00	670.00
IUUC-Pma-094581	Petromyzon marinus	63.86	7.00e-178	615.00
IUUC-Pno-095139	Phaeosphaeria nodorum	56.97	6.00e-110	389.00
IUUC-Ppa-095192	Physcomitrella patens	58.99	6.00e-134	469.00
IUUC-Pfo-096309	Poecilia formosa	65.40	0.00e+00	632.00
IUUC-Pab-098762	Pongo abelii	48.51	8.00e-120	421.00
IUUC-Pop-098924	Populus trichocarpa	57.70	2.00e-124	437.00
IUUC-Pca-100565	Procavia capensis	66.80	3.00e-179	619.00
IUUC-Ppe-101924	Prunus persica	53.88	3.00e-130	456.00
IUUC-Pva-102602	Pteropus vampyrus	64.06	0.00e+00	634.00
IUUC-Pgr-103466	Puccinia graminis	47.90	6.00e-110	389.00
IUUC-Ptt-103888	Puccinia triticina	54.99	6.00e-100	356.00
IUUC-Pte-104097	Pyrenophora teres	46.36	4.00e-125	440.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	42.62	4.00e-107	380.00
IUUC-Rno-105028	Rattus norvegicus	65.98	0.00e+00	667.00
IUUC-Sce-106240	Saccharomyces cerevisiae	45.92	4.00e-91	327.00
IUUC-Sha-106538	Sarcophilus harrisii	57.14	5.00e-157	545.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	51.28	1.00e-114	404.00
IUUC-Spo-108056	Schizosaccharomyces pombe	52.00	2.00e-112	397.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	48.10	8.00e-121	425.00
IUUC-Smo-108878	Selaginella moellendorffii	53.99	6.00e-134	469.00
IUUC-Sit-110550	Setaria italica	51.24	2.00e-123	434.00
IUUC-Sly-111446	Solanum lycopersicum	53.62	9.00e-129	451.00
IUUC-Stu-112491	Solanum tuberosum	53.39	2.00e-128	450.00
IUUC-Sar-112962	Sorex araneus	63.84	3.00e-94	336.00
IUUC-Sbi-114489	Sorghum bicolor	68.15	1.00e-118	418.00
IUUC-Sre-115222	Sporisorium reilianum	58.40	3.00e-120	424.00
IUUC-Ssc-116171	Sus scrofa	66.36	0.00e+00	674.00
IUUC-Tgu-116878	Taeniopygia guttata	59.37	5.00e-162	562.00
IUUC-Tru-118222	Takifugu rubripes	64.65	3.00e-180	622.00
IUUC-Tni-119863	Tetraodon nigroviridis	65.21	0.00e+00	625.00
IUUC-Tca-121599	Theobroma cacao	54.08	3.00e-127	446.00
IUUC-Tre-122249	Trichoderma reesei	61.22	6.00e-122	429.00
IUUC-Tvi-122675	Trichoderma virens	48.02	1.00e-122	431.00
IUUC-Tae-124272	Triticum aestivum	67.20	2.00e-124	437.00
IUUC-Tur-126545	Triticum urartu	57.67	1.00e-98	351.00
IUUC-Tme-127151	Tuber melanosporum	50.60	3.00e-137	480.00
IUUC-Tbe-128056	Tupaia belangeri	72.64	5.00e-135	471.00
IUUC-Ttr-129055	Tursiops truncatus	65.80	0.00e+00	665.00
IUUC-Uma-129555	Ustilago maydis	57.85	5.00e-120	423.00
IUUC-Vda-130027	Verticillium dahliae	47.41	4.00e-124	437.00
IUUC-Vvi-131749	Vitis vinifera	53.07	7.00e-130	455.00
IUUC-Xtr-132808	Xenopus tropicalis	69.46	0.00e+00	649.00
IUUC-Xma-133183	Xiphophorus maculatus	65.40	0.00e+00	632.00
IUUC-Yli-134584	Yarrowia lipolytica	58.27	2.00e-127	447.00
IUUC-Zma-135262	Zea mays	67.83	2.00e-118	417.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence