iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115241

Ensembl Protein ID

ENSSSCP00000025814.1

UniProt Accession

I3LNY9; I3LNY9_PIG

Genbank Protein ID

ENSSSCP00000025814

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

FP312782

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000022066.1	ENSSSCT00000025411.1	ENSSSCP00000025814.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	94.15	0.00e+00	914.00	IUUC-Hsa-045784
E3 activity/RING/RING	27.42	2.00e-28	122.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sus scrofa

Protein Sequence
(Fasta)

MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKS SEPTPQPHRP LDPLAMHSAY DRASSVPRTP LTGPNIDYPV LYGKYLNGLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCGCGGCAT AGGCCCCGCC CGCGAGTGGA GGGCAGTCAC GTGACGCGAC GGCTGGGGGC 60
TCCCGGCGCG GGGGACGCTG GTGGCCAAGA TGGCGGCGGA GCTGGTGGAG GCCAAAGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

KEGG

ssc:100624971

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	95.28	0.00e+00	899.00
IUUC-Apl-003765	Anas platyrhynchos	83.07	0.00e+00	830.00
IUUC-Ame-010763	Astyanax mexicanus	61.33	2.00e-147	515.00
IUUC-Bta-012369	Bos taurus	97.86	0.00e+00	933.00
IUUC-Cja-019450	Callithrix jacchus	93.18	0.00e+00	901.00
IUUC-Cfa-020933	Canis familiaris	97.09	0.00e+00	914.00
IUUC-Cpo-022112	Cavia porcellus	93.46	0.00e+00	865.00
IUUC-Csa-023913	Chlorocebus sabaeus	82.21	0.00e+00	733.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	28.47	3.00e-35	142.00
IUUC-Dre-027609	Danio rerio	59.82	1.00e-142	499.00
IUUC-Dno-029664	Dasypus novemcinctus	76.41	8.00e-156	543.00
IUUC-Ete-032988	Echinops telfairi	92.74	1.00e-172	598.00
IUUC-Eca-034430	Equus caballus	90.82	0.00e+00	886.00
IUUC-Fca-035968	Felis catus	96.92	1.00e-168	585.00
IUUC-Fal-037449	Ficedula albicollis	84.25	0.00e+00	817.00
IUUC-Fso-038103	Fusarium solani	34.72	6.00e-27	114.00
IUUC-Gmo-038925	Gadus morhua	61.76	2.00e-140	491.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.48	8.00e-30	124.00
IUUC-Gga-040362	Gallus gallus	86.38	0.00e+00	861.00
IUUC-Gac-042353	Gasterosteus aculeatus	59.82	7.00e-135	473.00
IUUC-Ggo-044810	Gorilla gorilla	92.01	0.00e+00	863.00
IUUC-Hsa-045784	Homo sapiens	94.15	0.00e+00	913.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	92.67	0.00e+00	887.00
IUUC-Lch-049727	Latimeria chalumnae	71.96	1.00e-152	532.00
IUUC-Loc-052354	Lepisosteus oculatus	53.76	2.00e-122	432.00
IUUC-Laf-054261	Loxodonta africana	93.98	0.00e+00	915.00
IUUC-Mcc-054931	Macaca mulatta	92.59	0.00e+00	896.00
IUUC-Meu-056468	Macropus eugenii	88.13	0.00e+00	880.00
IUUC-Mpo-057405	Magnaporthe poae	33.06	5.00e-29	122.00
IUUC-Mtr-058267	Medicago truncatula	33.33	3.00e-18	87.00
IUUC-Mga-059981	Meleagris gallopavo	89.35	0.00e+00	712.00
IUUC-Mvi-060421	Microbotryum violaceum	29.07	1.00e-27	117.00
IUUC-Mmr-061181	Microcebus murinus	91.67	0.00e+00	857.00
IUUC-Mdo-062345	Monodelphis domestica	87.74	0.00e+00	879.00
IUUC-Mmu-063197	Mus musculus	87.77	0.00e+00	848.00
IUUC-Mpu-066275	Mustela putorius furo	95.33	0.00e+00	908.00
IUUC-Mlu-067194	Myotis lucifugus	96.31	0.00e+00	929.00
IUUC-Ncr-068929	Neurospora crassa	27.70	1.00e-27	117.00
IUUC-Ont-072227	Oreochromis niloticus	59.82	1.00e-139	489.00
IUUC-Obr-076179	Oryza brachyantha	32.58	1.00e-20	94.70
IUUC-Ola-086865	Oryzias latipes	61.61	5.00e-138	484.00
IUUC-Oga-088945	Otolemur garnettii	94.15	0.00e+00	915.00
IUUC-Oar-089412	Ovis aries	94.14	0.00e+00	884.00
IUUC-Ptr-091550	Pan troglodytes	85.26	0.00e+00	641.00
IUUC-Pan-092183	Papio anubis	93.57	0.00e+00	910.00
IUUC-Psi-093003	Pelodiscus sinensis	84.44	0.00e+00	842.00
IUUC-Pfo-096704	Poecilia formosa	60.23	7.00e-143	500.00
IUUC-Pab-097923	Pongo abelii	97.64	0.00e+00	766.00
IUUC-Pca-100249	Procavia capensis	79.06	3.00e-146	510.00
IUUC-Pva-102562	Pteropus vampyrus	92.26	0.00e+00	855.00
IUUC-Rno-105762	Rattus norvegicus	88.54	0.00e+00	852.00
IUUC-Sce-106398	Saccharomyces cerevisiae	34.10	8.00e-29	122.00
IUUC-Sha-107253	Sarcophilus harrisii	86.96	0.00e+00	870.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	28.07	3.00e-29	123.00
IUUC-Sar-113149	Sorex araneus	86.57	2.00e-128	452.00
IUUC-Tgu-116884	Taeniopygia guttata	84.02	0.00e+00	806.00
IUUC-Tru-118031	Takifugu rubripes	60.50	1.00e-146	512.00
IUUC-Tni-119766	Tetraodon nigroviridis	60.50	6.00e-142	496.00
IUUC-Ttr-128556	Tursiops truncatus	87.50	0.00e+00	753.00
IUUC-Xtr-131866	Xenopus tropicalis	76.58	0.00e+00	764.00
IUUC-Xma-133963	Xiphophorus maculatus	60.50	1.00e-136	479.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence